Epidemiology and disease burden from allergic disease in Scotland:                analyses of national databases

Anandan, Chantelle; Gupta, Ramyani; Simpson, Colin R; Fischbacher, Colin; Sheikh, Aziz

doi:10.1258/jrsm.2009.090027

Cited by 72 publications

(57 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The Scottish Health Survey is an important source of data to assess the health status of the Scottish population across a number of health indicators, including respiratory and cardiovascular diseases. 23,24 The survey processes have followed well-designed and rigorous methodologies of data collection and management, employing well-accepted measurement tools for gathering valid responses. The surveys are random samples of the general Scottish population; hence, our findings are likely to be generalisable to the wider population of Scottish women aged 16-45 years.…”

Section: Discussionmentioning

confidence: 99%

Hormonal contraceptives and asthma in women of reproductive age: analysis of data from serial national Scottish Health Surveys

Nwaru

Sheikh

2015

J R Soc Med

View full text Add to dashboard Cite

Objectives: Sex steroid hormones may explain known gender-related variations in asthma prevalence and clinical manifestation. We investigated the relationship between use of hormonal contraceptives and asthma in women, and assessed evidence of biological interaction between use of hormonal contraceptives and body mass index in this relationship. Design: Population-based analysis using data from serial Exposure: Current use of hormonal contraceptives. Main outcome measures: Self-reported current physiciandiagnosed asthma, current wheezing symptoms, wheezing attacks and treatment for asthma or wheeze. Results: Women comprising 30.9% (95% confidence interval 29.3-32.5) were currently using any hormonal contraceptive and current physician-diagnosed asthma was present in 6.5% (95% confidence interval 5.7-7.4). Use of any hormonal contraceptive was associated with reduced risk of current physician-diagnosed asthma (odds ratio 0.68; 95% confidence interval 0.47-0.98) and receiving !3 asthma care episodes (odds ratio 0.45; 95% confidence interval 0.25-0.82), but the evidence was equivocal for wheezing attacks. Use of hormonal contraceptives among overweight or obese women was non-statistically significantly associated with asthma, but there was 42-135% increased risk in overweight and obese non-contraceptive using women. Conclusions: Use of hormonal contraceptives may reduce asthma exacerbations and number of care episodes. Overweight and obese non-contraceptive-using women may be at increased risk of asthma. Prospective studies are now needed to confirm these findings. Both oestrogen and progesterone may stimulate smooth airway muscle function and inhibit the activities of TH2 responses. Future studies should investigate these underlying mechanisms.

show abstract

Section: Discussionmentioning

confidence: 99%

Hormonal contraceptives and asthma in women of reproductive age: analysis of data from serial national Scottish Health Surveys

Nwaru

Sheikh

2015

J R Soc Med

View full text Add to dashboard Cite

show abstract

“…1,2 The proportion of children experiencing allergic problems is significantly higher than this (approximately 50%). 3 The vast majority of patients suffering from allergic disorders are treated in the community, and care for the majority of these patients will be provided almost exclusively by their general practitioner (GP) and/or practice nurse.…”

Section: Introductionmentioning

confidence: 99%

Follow-up survey of general practitioners' perceptions of UK allergy services

Hazeldine

Worth

Sheikh

2010

Primary Care Respiratory Journal

View full text Add to dashboard Cite

Background: A UK survey of general practitioners (GPs) in 2002 found that they perceived allergy care throughout the UK National Health Service (NHS) to be poor. We conducted a follow-up survey in 2009 to see if GPs' perceptions had changed.Objectives: To determine GP perceptions of allergy care in the NHS in the wake of recent Government reports into allergy care, and to compare the findings of this survey to a similar survey conducted in 2002.Methods: A cross-sectional postal survey of 500 UK GPs was conducted, using an adapted version of the 2002 questionnaire, modified to reflect recent developments in primary care. Results:We obtained valid responses from 149 GPs, 87% of whom were based in England. 74% were GP principals and 63% worked in training practices. Most GPs (71%; 95%CI 63-79) rated overall NHS allergy care as poor, expressing concern about both primary care and access to allergy specialists. There were no significant differences in GPs' perceptions of the quality of allergy care provided in primary (p=0.33) and secondary care (p=0.97) or access to specialists (p=0.

show abstract

“…2,3 In children in the UK this proportion increases to around 50%. 4 In parallel with this sharp increase in prevalence there has been an accompanying increase in disease severity, 1 particularly in those with more systemic allergic disorders.…”

Section: Introductionmentioning

confidence: 99%

Identifying current training provision and future training needs in allergy available for UK general practice trainees: national cross-sectional survey of General Practitioner Specialist Training programme directors

Ellis

Rafi

Smith

et al. 2012

Primary Care Respiratory Journal

View full text Add to dashboard Cite

show abstract

Epidemiology and disease burden from allergic disease in Scotland: analyses of national databases

Cited by 72 publications

References 12 publications

Hormonal contraceptives and asthma in women of reproductive age: analysis of data from serial national Scottish Health Surveys

Hormonal contraceptives and asthma in women of reproductive age: analysis of data from serial national Scottish Health Surveys

Follow-up survey of general practitioners' perceptions of UK allergy services

Identifying current training provision and future training needs in allergy available for UK general practice trainees: national cross-sectional survey of General Practitioner Specialist Training programme directors

Contact Info

Product

Resources

About