Epidemiology and Diagnosis of Pediatric Obstructive Sleep Apnea

DelRosso, Lourdes M.

doi:10.1016/j.cppeds.2015.10.009

Cited by 54 publications

(48 citation statements)

References 14 publications

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“…The items of PSQ-SRBD focused on three prominent symptom complexes: snoring, excessive daytime sleepiness and inattentive/hyperactive behaviour, which encompassed the clinical manifestations in the latest criteria of the ICSD-3 26 27. Since SDB affects children of preschool and school age,28 with the peak prevalence at 2–8 years due to the high incidence of tonsillar and adenoidal hypertrophy,29 we preferred to sample children >3 years of age. Moreover, Chervin et al 12 focused on the age group 2–18 years old in the original PSQ research, and the Spanish30 and Taiwan versions of the PSQ31 on children aged 6–16 years old, corresponding to the age range used in the present study.…”

Section: Discussionmentioning

confidence: 99%

Systematic investigation of childhood sleep-disordered breathing (SDB) in Beijing: validation of survey methodology

Tai

et al. 2018

BMJ Open

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ObjectiveTo systematically investigate and validate the survey methodology for the epidemiological study of childhood sleep-disordered breathing (SDB) in mainland China using the Mandarin version of the Pediatric Sleep Questionnaire-Sleep-Related Breathing Disorder (PSQ-SRBD).DesignA cross-sectional study using randomised, stratified, multistage, cluster sampling method.SettingA total of 11 kindergartens, 7 primary schools and 8 middle schools from 7 districts of Beijing, China.ParticipantsA total of 9198 children with valid questionnaires (4736 boys and 4462 girls; age range 3.0–14.4 years) were included.Primary and secondary outcome measuresData on sociodemographic characteristics and PSQ-SRBD were collected. The score on PSQ-SRBD and the included factors were calculated with the effective data after data cleaning. Logistic regression and factor analysis with the principal components method were used to evaluate the validity of the questionnaire; reliability was assessed by retesting 5% of the respondents after 2±4 weeks of the initial test, and the intraclass correlation coefficient was calculated.ResultsThe effective response rate of80.54% matched the sociodemographic characteristics of the respondents with respect to age group ratio and sex ratio in Beijing. With regard to construct validity of the PSQ-SRBD, the item score, except that of ‘delayed growth’, was highly correlated to the SRBD score as assessed by the logistic regression model. The exploratory factor analysis displayed a credible construct validity, with majority of the items grouped as the original dimensions. The test–retest reliability coefficient of each dimension’s score ranged from 0.758 to 0.901, with an SRBD score of 0.730 indicating significant retest reliability.ConclusionsThis study conducted and validated a successful survey methodology for investigation of childhood SDB in Beijing, China. The questionnaire demonstrated credible construct validity and retest reliability, thereby supporting the applicability and generalisability of the PSQ-SRBD in a large epidemiological survey of childhood SDB in China.

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Section: Discussionmentioning

confidence: 99%

Systematic investigation of childhood sleep-disordered breathing (SDB) in Beijing: validation of survey methodology

Tai

et al. 2018

BMJ Open

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“…Obstructive Sleep Apnea (OSA) is a common respiratory disorder characterized by recurrent nocturnal episodes of breathing interruption due to the total or partial collapse of upper airway 1 and affects 1.2-5.7% of children. 2 The peak of incidence occurs at 2-8 years and the most common cause of OSA in children is enlarged tonsils and adenoids. 2,3 Moreover, OSA is associated with morbidity that involves central nervous system (CNS), cardiovascular and metabolic systems.…”

Section: Introductionmentioning

confidence: 99%

“…2 The peak of incidence occurs at 2-8 years and the most common cause of OSA in children is enlarged tonsils and adenoids. 2,3 Moreover, OSA is associated with morbidity that involves central nervous system (CNS), cardiovascular and metabolic systems. 4 The recurrent hypoxia is suggested as the main cause of altered autonomic nervous system (ANS) in those patients.…”

Section: Introductionmentioning

confidence: 99%

Heart rate variability in children with obstructive sleep apnea: a systematic review

Sequeira¹

2020

SMDIJ

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“…Its onset usually occurs between two and eight years of age, coinciding with the peak tonsil growth . The pathophysiology of paediatric OSA is multifactorial and can be divided into factors that affect upper airway collapsibility, factors that produce anatomic narrowing, or a combination of both . Other epidemiologic risk factors include obesity, African American ethnicity, family history of OSA, and socioeconomic/environmental status .…”

Section: Introductionmentioning

confidence: 99%

“…10 The pathophysiology of paediatric OSA is multifactorial and can be divided into factors that affect upper airway collapsibility, factors that produce anatomic narrowing, or a combination of both. 11 Other epidemiologic risk factors include obesity, African American ethnicity, family history of OSA, and socioeconomic/environmental status. 12 Among the aetiopathogenic factors, adenotonsillar hypertrophy is the most common cause of paediatric OSA.…”

Section: Introductionmentioning

confidence: 99%

Management of paediatric obstructive sleep apnoea: A systematic review and network meta‐analysis

Lin

et al. 2019

Int J Paed Dentistry

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Background Obstructive sleep apnoea (OSA) affects many children, and adenotonsillar hypertrophy is the most common cause of paediatric OSA. Aim Despite the growing treatment options, there is no comprehensive comparison of all interventions. We aimed to compare and rank the effectiveness of various treatments in a network meta‐analysis. Design Literature was searched from inception to 13 May 2018 for paediatric OSA with adenotonsillar hypertrophy. The outcomes were the changes in apnoea‐hypopnea index (AHI), oxyhaemoglobin desaturation index (ODI), and lowest arterial oxygen saturation (SaO2). Frequentist approach to network meta‐analysis was used. Treatment hierarchy was summarized according to the surfaces under the cumulative ranking curves. Results Fourteen trials comprising 1064 paediatric OSA participants evaluating ten interventions (adenotonsillectomy, adenotonsillectomy + pharyngoplasty, adenotonsillotomy, antimicrobial therapy, steroids, leukotriene receptor antagonists [LTRAs], steroids + LTRAs, rapid maxillary expansion [RME], placebo, and no treatment) were identified for network meta‐analysis. In terms of effectiveness in AHI reduction, surgical approach was still the most effective intervention than no treatment. RME was one of the most effective interventions to improve lowest SaO2. No comparisons showed statistical significance in reducing ODI. Conclusions Irrespective of the intervention used, complete resolution of OSA was not achieved in most trials.

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Epidemiology and Diagnosis of Pediatric Obstructive Sleep Apnea

Cited by 54 publications

References 14 publications

Systematic investigation of childhood sleep-disordered breathing (SDB) in Beijing: validation of survey methodology

Systematic investigation of childhood sleep-disordered breathing (SDB) in Beijing: validation of survey methodology

Heart rate variability in children with obstructive sleep apnea: a systematic review

Management of paediatric obstructive sleep apnoea: A systematic review and network meta‐analysis

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