Epidemiology and clinical features of obsessive-compulsive disorder during pregnancy and postpartum period: a review

Abstract

Gebelik ve postpartum dönemde obsesif kompulsif bozukluğun epidemiyolojisi ve klinik öze-likleri: Bir gözden geçirme Bu makale obsesif kompulsif bozukluğun (OKB) gebelik ve postpartum dönemde epidemiyolojisi ve klinik özel-likleri ile ilgili güncel literatürü gözden geçirmektedir. Konu ile ilgili bildiriler önemli sınırlılıklar ve farklı sonuç-lara içermektedir. Bununla birlikte OKB'nin prevalans ve insidans oranları genel toplumda bildirilenlere göre bu iki dönemde daha yüksektir. Gebelik ve puerperiumda en sık obsesyonlar bulaşma ve saldırganlık obsesyonlarıdır. Saldırganlık obsesyonları postpartum dönemdeki kadınlarda bu dönemde olmayan kadınlara göre daha sık gözlenmektedir. Sonuç olarak, gebelik ve postpartum dönemler OKB'nin ortaya çıkmasında riskli dönemler olarak görünmektedir. Dolayısıyla bu dönemde olan kadınlar OKB yönünden taranmalıdır. Epidemiology and clinical features of obsessivecompulsive disorder during pregnancy and postpartum period: a reviewIn this study we reviewed the current literature on the epidemiology and clinical features of obsessive-compulsive disorder (OCD) during pregnancy and postpartum period. The available reports on this topic have significant limitations and heterogenous methods. However, the prevalence and incidence rates of OCD reported during these two reproductive periods are higher than the rates estimated in the general population. The most common obsessions in pregnancy and puerperium were contamination and aggressive obsessions. Aggressive obsessions are observed more frequently in postpartum women compared to non-postpartum women. Pregnancy and postpartum periods appear to be risk periods for new-onset OCD. For this reason, pregnant and postpartum women should be screened with respect to OCD.

Obsessive–Compulsive Disorder in the Postpartum Period: Diagnosis, Differential Diagnosis and Management

“…Both syndromal and subsyndromal symptoms of OCD are common after childbirth. The prevalence estimates of postpartum OCD vary depending on the study population, screening/diagnostic instruments used and the duration of the postpartum period [10]. A meta-analysis of seven studies of OCD in postpartum (up to 12 months) women using structured diagnostic interviews reported a prevalence of 2.43% [11].…”

Anxiety Disorders in Pregnancy and the Postpartum Period

“…For this reason, their symptoms often impair their ability to care their infants. This situation may give rise to depressive symptoms [29][30].…”

“…There are several case reports showing that pregnancy and postpartum period are associated with the onset of OCD more frequently than other life events [29].…”

“…Many authors noted that the aggressive obsessions had 9 times more chances of occurring in a postpartum woman with OCD than in a healthy postpartum woman. The aggressive obsessions mostly include fear of harming the baby [29,33]. In some instances, sufferers report obsessions having to do with accidental harm, while in others the obsessions involve unwanted thoughts or ideas of intentionally harming the newborn.…”

Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood

“…Maternal depression during pregnancy is an important condition because potential adverse effects on the fetal development 5). Several studies investigated the effects of maternal depression on birth outcomes 6). Although there is no clear consensus as yet, according to conclusions of these studies pregnancy depression seems to be associated with low birth weight and shorter duration of pregnancy 7–10)…”