Epidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic review

Mac, Tu Luong; Tran, Duc Si; Quet, Fabrice; Odermatt, Peter; Preux, Pierre‐Marie; Tan, Chong Tin

doi:10.1016/s1474-4422(07)70127-8

Cited by 272 publications

(288 citation statements)

References 81 publications

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“…It has been scientifically proved that female sex hormones (estrogen and progesterone) affect the threshold of seizures to some extent which leads to the difference [21]. The incidence of epilepsy has a bimodal distribution with a peak in the first decade and a second peak in elderly which is also proven in this study as there is a maximal incidence before 10 y (84% children<10 y).…”

Section: Discussionsupporting

confidence: 71%

A Prospective Study of Drug Utilization Pattern of Anti-Epileptic Drugs and Their Adverse Effects in a Tertiary Care Hospital

Sylvia

Chidambaranathan

et al. 2017

Int J Curr Pharm Sci

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Objective: Epilepsy or seizure disorder is a common neurologic disorder in the pediatric age group and occurs with a frequency of 4-6 cases per thousand children. Epilepsy, particularly childhood epilepsy, remains a challenge to treat. The management of epilepsy is primarily based on the use of anti-epileptic drugs. Surgery and diet therapy are the other modes of treating childhood seizures. To get an insight into the utilization pattern of anti-epileptic drugs (AEDs) used in pediatric seizures.Methods: This prospective, longitudinal study was conducted for a period of 8 months in Paediatric Neurology Department of a tertiary care teaching hospital. The data collected from 50 children at the end of the study, were compiled in a specially designed data form and were analyzed. Results:The distribution of paediatric seizures was found to be high in male children (62%) and in the age group of 2 to 5 y (46%). The majority of the children (70%) were diagnosed with Generalized Tonic-clonic seizures. Sodium valproate was the commonly prescribed AED in all forms of seizures followed by Carbamazepine (18%), Phenobarbitone (4%) and Phenytoin Sodium (4%). AEDs were mostly prescribed as monotherapy (82%). Adverse reactions noted during this study was minimal (12%). Conclusion:Sodium valproate, a conventional AED still remains the commonly prescribed AED for all types of seizures in children aged 2 to 16 y and also was found to be effective and safe.

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Section: Discussionsupporting

confidence: 71%

A Prospective Study of Drug Utilization Pattern of Anti-Epileptic Drugs and Their Adverse Effects in a Tertiary Care Hospital

Sylvia

Chidambaranathan

et al. 2017

Int J Curr Pharm Sci

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“…The average prevalence rate in 32 studies from different parts of the world has been estimated at 5.16/1000 [23]. In Pakistan, 11.1 (an average in urban and rural areas) [14], While some studies reported 9.8 [15,24] There were so many studies that did not show any significant gender difference [26],But most of the surveys show high prevalence percentages in male; which is assumed to reflect the contribution of etiologic factors such as head trauma known to be more frequent in males [12,27]. Similarly high prevalence percentage in female at primary (60.7%) and secondary (35.7); while these percentages were higher at tertiary and professional level in male population; 20.9% and 12.8% respectively.…”

Section: Discussionmentioning

confidence: 99%

Awareness and Prevalence of Epilepsy; a Study in Educational Hubs at Sheringal, Khyber Pakhtunkhwa, Pakistan

2018

ARC Journal of Neuroscience

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“…It Concerned with perception and recognition of auditory stimuli (hearing) and memory [58][59][60] (hippocampus).…”

Section: Brain Configurationmentioning

confidence: 99%

A Review on Management of Epilepsy Complications in Health Care Practice

Male¹

2017

WJPR

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Epidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic review

Cited by 272 publications

References 81 publications

A Prospective Study of Drug Utilization Pattern of Anti-Epileptic Drugs and Their Adverse Effects in a Tertiary Care Hospital

A Prospective Study of Drug Utilization Pattern of Anti-Epileptic Drugs and Their Adverse Effects in a Tertiary Care Hospital

Awareness and Prevalence of Epilepsy; a Study in Educational Hubs at Sheringal, Khyber Pakhtunkhwa, Pakistan

A Review on Management of Epilepsy Complications in Health Care Practice

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