Epidemiological trends of HIV/HCV coinfection in Spain, 2015–2019

Abstract

The members of the 'GeSIDA 8514 Study Group' are given in Appendix section.

Treatment as prevention effect of direct-acting antivirals on primary hepatitis C virus incidence: findings from a multinational cohort between 2010 and 2019

“…Studies conducted within InCHEHC countries have reported high initial DAA uptake rates, 6,19,23,31,32 and we observed an increase in the proportion treated during the limited and broad DAA access period compared to the pre-DAA period in all countries. However, some countries have reported that HCV treatment uptake has declined since DAAs were first introduced, and those remaining to be treated are less engaged in care, reducing opportunities for HCV care.…”

“…Another study using InCHEHC data showed that HCV reinfection remained stable or declined in most evaluated countries following broad access to DAAs, although declines were less pronounced than in primary incidence. 21,22 Despite high DAA treatment uptake in Spain, 23 broad access to DAAs led to a smaller absolute decline in HCV incidence than in other countries, possibly due to cohort characteristics: Spaniards were younger and had more recently diagnosed HIV infections, so potentially engaged in more high-risk behaviours. Sustained broad access to DAAs and higher uptake of other (non-) biomedical preventive interventions are needed in countries with expanding HCV epidemics prior to DAA access to achieve declines similar to those in countries with stable or declining trends.…”

HBV and HCV Co-Infection in Chinese Newly Diagnosed HIV+ Subjects in 2015 and 2023: A Cross-Sectional Study

“…The rate of HIV/HCV co-infection in 2023 was higher than that of UK Afro-descendants in 2021 (1.3%) and Ethiopia in 2022 (1.7%) but in line with the 2.4% to 5% worldwide rate during 1991 to 2018 [10]. A notable decline in HIV/HCV co-infection was seen in Spain in 2010 (8.3%) and 2019 (2.2%) [15,16], which is in accordance with the findings in this study, although it is still greater than in high-and middle-income nations like Europe.…”