Epidemiological surveillance of<i>Campylobacter jejuni</i>in chicken, dairy cattle and diarrhoea patients

Huang, Jinlin; Xu, Hao; Bao, Guangyu; Zhou, Xiaohui; Ji, Duan; Zhang, G.; Liu, P. H.; Jiang, Feng; Pan, Zhiming; Liu, X. F.; Jiao, Xinan

doi:10.1017/s0950268809002039

Cited by 43 publications

(32 citation statements)

References 21 publications

(34 reference statements)

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“…Whether ggt-negative C. jejuni clones are capable to acquire this marker through genetic exchange with ggt-positive clones, thereby promoting its successful colonization in the chicken gut, has yet to be examined. Also, several other studies revealed the presence of identical C. jejuni clones in bovines, chickens, and humans (Nielsen et al 1997, On et al 1998, Gilpin et al 2008, Ragimbeau et al 2008, Huang et al 2009, and even turkeys, sheep, water, dogs, and ostriches (Siemer et al 2004). Recently, it was shown by molecular typing that Campylobacter strains from a broiler house and from an adjacent dairy farm were similar to those subsequently detected in the flock, indicating the importance of horizontal transmission and the risk of transmission of Campylobacter on multispecies farms (Ridley et al 2011).…”

Section: Sources For Horizontal Campylobacter Transmission To Broilermentioning

confidence: 92%

Poultry as a Host for the Zoonotic PathogenCampylobacter jejuni

Hermans

Pasmans²,

Messens³

et al. 2012

Vector-Borne and Zoonotic Diseases

221

157

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Campylobacteriosis is the most reported foodborne gastroenteritic disease and poses a serious health burden in industrialized countries. Disease in humans is mainly caused by the zoonotic pathogen Campylobacter jejuni. Due to its wide-spread occurrence in the environment, the epidemiology of Campylobacter remains poorly understood. It is generally accepted, however, that chickens are a natural host for Campylobacter jejuni, and for Campylobacter spp. in general, and that colonized broiler chicks are the primary vector for transmitting this pathogen to humans. Several potential sources and vectors for transmitting C. jejuni to broiler flocks have been identified. Initially, one or a few broilers can become colonized at an age of > 2 weeks until the end of rearing, after which the infection will rapidly spread throughout the entire flock. Such a flock is generally colonized until slaughter and infected birds carry a very high C. jejuni load in their gastrointestinal tract, especially the ceca. This eventually results in contaminated carcasses during processing, which can transmit this pathogen to humans. Recent genetic typing studies showed that chicken isolates can frequently be linked to human clinical cases of Campylobacter enteritis. However, despite the increasing evidence that the chicken reservoir is the number one risk factor for disease in humans, no effective strategy exists to reduce Campylobachter prevalence in poultry flocks, which can in part be explained by the incomplete understanding of the epidemiology of C. jejuni in broiler flocks. As a result, the number of human campylobacteriosis cases associated with the chicken vector remains strikingly high.

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Section: Sources For Horizontal Campylobacter Transmission To Broilermentioning

confidence: 92%

Poultry as a Host for the Zoonotic PathogenCampylobacter jejuni

Hermans

Pasmans²,

Messens³

et al. 2012

Vector-Borne and Zoonotic Diseases

221

157

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“…In addition, the application of bacterial pathogen typing (Ertas et al 2004;Takahashi et al 2006;Wilson et al 2008;Hannon et al 2009;Huang et al 2009;Sheppard et al 2009) and direct detection of host-species specific bacterial DNA (Bernhard & Field 2000b;Dick et al 2005a) could be useful in identifying sources (microbial source tracking; MST) of faecal contamination in surface waters. While library-and culture-independent MST methods are inexpensive, quick, and easy to use (Bernhard & Field 2000b), molecular subtyping methods for pathogens may provide confirmation, and in some cases greater discrimination in the identification of faecal sources of contamination.…”

Section: Introductionmentioning

confidence: 99%

The occurrence and sources of Campylobacter spp., Salmonellaenterica and Escherichia coli O157:H7 in the Salmon River, British Columbia, Canada

Jokinen

Schreier

Mauro

et al. 2009

Journal of Water and Health

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In this study, we wished to assess the prevalence and determine the sources of three zoonotic bacterial pathogens (Salmonella, Campylobacter, and Escherichia coli O157:H7) in the Salmon River watershed in southwestern British Columbia. Surface water, sewage, and animal faecal samples were collected from the watershed. Selective bacterial culture and PCR techniques were used to isolate these three pathogens and indicator bacteria from these samples and characterize them. Campylobacter was the most prevalent pathogen in all samples, followed by Salmonella, and E. coli O157:H7. E. coli O157:H7 and Salmonella isolation rates from water, as well as faecal coliform densities correlated positively with precipitation, while Campylobacter isolation rates correlated negatively with precipitation. Analysis of DNA extracted from water samples for the presence of Bacteroides host-species markers, and comparisons of C. jejuni flaA-RFLP types and Salmonella serovars from faecal and water samples provided evidence that human sewage and specific domestic and wild animal species were sources of these pathogens; however, in most cases the source could not be determined or more than one source was possible. The frequent isolation of these zoonotic pathogens in the Salmon River highlights the risks to human health associated with intentional and unintentional consumption of untreated surface waters.

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“…ampylobacter jejuni is the major foodborne pathogen that causes human bacterial gastroenteritis (1,2). Chicken is a major reservoir of C. jejuni (3), and contaminated chicken products are recognized as the main source of C. jejuni-related human infections (4).…”

mentioning

confidence: 99%

Correlation between gyrA and CmeR Box Polymorphism and Fluoroquinolone Resistance in Campylobacter jejuni Isolates in China

Zhāng

Cheng

Luo

et al. 2017

Antimicrob Agents Chemother

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Sequence analysis of 79 ciprofloxacin-resistant Campylobacter jejuni isolates collected in China showed resistance-related sequence variations in gyrA and CmeR-Box. All the isolates contain an identical Thr-86-Ile substitution in GyrA. Several novel CmeR-Box variations, including point substitutions, deletion, and insertion, were identified. The point insertion or deletion led to dramatically reduced binding of CmeR to the cmeABC promoter, which significantly increases the expression of cmeABC and contributes to the high fluoroquinolone resistance.

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Epidemiological surveillance ofCampylobacter jejuniin chicken, dairy cattle and diarrhoea patients

Cited by 43 publications

References 21 publications

Poultry as a Host for the Zoonotic PathogenCampylobacter jejuni

Poultry as a Host for the Zoonotic PathogenCampylobacter jejuni

The occurrence and sources of Campylobacter spp., Salmonellaenterica and Escherichia coli O157:H7 in the Salmon River, British Columbia, Canada

Correlation between gyrA and CmeR Box Polymorphism and Fluoroquinolone Resistance in Campylobacter jejuni Isolates in China

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