Epidemiological surveillance of cystic echinococcosis in rural population of Tierra del Fuego, Argentina, 1997–2006

F, Zanini; Suárez, Carlos; Pérez, Héctor; Elissondo, Marı́a Celina

doi:10.1016/j.parint.2008.10.004

Cited by 11 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…While echinococcosis is primarily a human health problem, it is necessary to establish vigilance systems of the infection in man, especially in children (between 0/10 years old) or schoolchildren (between 6 and 14 years old), which can be efficiently carried out by using ultrasound (US) screenings (Frider et al, 2000;Larrieu et al, 2011;Perez et al, 2006). Early detection of CE children might facilitate the beginning of albendazole treatment (Brunetti et al, 2011;Frider & Larrieu, 2010;Larrieu, Mujica, et al, 2019;Larrieu, Uchiumi, et al, 2019;Zanini, Suárez, Pérez, & Elissondo, 2009).…”

Section: Surveillance In Humansmentioning

confidence: 99%

Control of cystic echinococcosis: Background and prospects

Larrieu

Gavidia

Lightowlers

2019

Zoonoses and Public Health

View full text Add to dashboard Cite

Cystic echinococcosis (CE), caused by Echinococcus granulosus, is a chronic and debilitating zoonotic larval cestode infection in humans, which is principally transmitted between dogs and domestic livestock, particularly sheep. Human CE occurs in almost all pastoral communities and rangeland areas of the underdeveloped and developed world. Control programmes against CE have been implemented in several endemic countries to reduce or eliminate the disease. New Zealand and Tasmania are examples of some of the first programmes to be undertaken (in insular territories) and which were very successful in the elimination of CE. The advent and proven effectiveness of praziquantel, plus the experience of insular models, produced high expectations for rapid advances in a second generation of control programmes undertaken in continental areas (Argentina, Uruguay and Chile). Nevertheless, only moderate gains in CE control have been made and the impact on prevalence among humans has been slight. A major impediment to the adoption of procedures that were successful in New Zealand and Tasmania has been the requirement to administer praziquantel to dogs in rural areas eight times per year over numerous years. In addition, there have been clear technological improvements made in the diagnosis of canine echinococcosis for surveillance, the genetic characterization of parasite strains and in vaccination against CE infection in livestock. In order to establish new paradigms and appropriate combinations of control strategies, we have carried out a review and discussion of the available control tools and control models. Control strategies must be suitable and sustainable to benefit the Echinococcosis–endemic areas primarily, which at the same time are the poorest regions of the world.

show abstract

Section: Surveillance In Humansmentioning

confidence: 99%

Control of cystic echinococcosis: Background and prospects

Larrieu

Gavidia

Lightowlers

2019

Zoonoses and Public Health

View full text Add to dashboard Cite

show abstract

“…Bites on the extremities were the most frequent types of bits in the studies [13][14][15]. In the current study, the region of the body in which the bites or mucosal contacts occurred was in the lower extremity in 60 (70.6%) patients and the upper extremity in 19 (22.4%) patients.…”

Section: Discussionmentioning

confidence: 44%

Efficacy of antibody levels in different post-exposure rabies vaccination programs

et al. 2016

View full text Add to dashboard Cite

Objectives. Rabies is a fatal acute viral zoonotic disease causing encephalomyelitis in humans and many other mammalian animals. Prophylaxis is vital since there is no treatment for rabies. This study was a comparison of antibody levels in patients who were vaccinated following different vaccinationprotocols. Methods. Eightyfive patients who were included in the rabies vaccination program who presented to the vaccination center of our clinic with the complaint of suspicious contact with rabies were included the study. In 61 (71.8%) patients a 2-1-1 vaccine program (Zagreb regimen) was implemented, and in 24 (28.2%) patients, a 5-dose rabies vaccine and rabies immune globulin (RIG) in a dose of 40 IU/kg (Essen regimen) was applied. Results. In patients on the 2-1-1 vaccine program, antibody levels on the 21 st day were greater than 0.5 IU/ml in 49 (80.3%) patients. Antibody levels on the 28 th day in the group that received the 5-dose rabies vaccine and rabies immune globulin administration was greater than 0.5 IU/ml in 17 (70.8%) patients. The difference between the two groups of vaccination programs was not statistically significant (p=0.344). Seroconversion rates for approximately one month after the last dose of vaccination in the serum samples were 90% and 75% in the groups with 2-1-1 vaccination, and RIG and 5-dose vaccinations, respectively. The differences were not statistically significant (p=0.071). Conclusions. Identification of similar seroconversion rates suggests that the 2-1-1 vaccination program may be a good alternative option to the standard vaccination program when RIG is unavailable.Eur Res J 2016;2(1):36-41

show abstract

“…In 1997-2006, ultrasound surveys of children 4-17 years of age showed prevalences of 0.0% and 0.9% among this population group (22,23). Thus, the pro gram in Tierra del Fuego was able to cut off transmis sion to humans almost completely in about 30 years.…”

Section: Tierra Del Fuegomentioning

confidence: 96%

Critical analysis of cystic echinococcosis control programs and praziquantel use in South America, 1974-2010

Larrieu¹,

F²

2012

Rev Panam Salud Publica

View full text Add to dashboard Cite

Cystic echinococcosis (CE) is one of the most prevalent zoonoses in Argentina, Brazil, Chile, Peru, and Uruguay. Control programs in South America were originally modeled after programs developed in insular territories, such as Tasmania and New Zealand. The advent and proven effectiveness of praziquantel, plus the experience of insular models, produced high expectations for rapid advances; however, after 30 years of praziquantel use, no endemic area in South America has obtained eradication. In fact, only modest gains in CE control have been made and impact on prevalence among humans has been slight. A major impediment has been the infrastructure needed to administer praziquantel to dogs in rural areas 8 times per year over numerous years, a requirement for rapid attack stage 1. Such an infrastructure has not been financially or politically sustainable in endemic areas, which tend to be the poorest. On the other hand, certain areas in Argentina have had success with simple and economically viable alternatives. Based primarily on continuous field work supported by the local community, these strategies have significantly decreased transmission to humans, the health sector's main objective. In addition, new possibilities and tools, such as the EG95 vaccine, are being evaluated; as are early detection and treatment of asymptomatic carriers.

show abstract

Epidemiological surveillance of cystic echinococcosis in rural population of Tierra del Fuego, Argentina, 1997–2006

Cited by 11 publications

References 15 publications

Control of cystic echinococcosis: Background and prospects

Control of cystic echinococcosis: Background and prospects

Efficacy of antibody levels in different post-exposure rabies vaccination programs

Critical analysis of cystic echinococcosis control programs and praziquantel use in South America, 1974-2010

Contact Info

Product

Resources

About