Epidemiological study of ulcerative proctocolitis in Indian migrants and the indigenous population of Leicestershire.

Probert, Chris; Venkataraman, Jayanthi; Pinder, D. C.; Wicks, A. C. B.; Mayberry, J F

doi:10.1136/gut.33.5.687

Cited by 244 publications

(173 citation statements)

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“…This observation of the increasing incidence of inflammatory bowel disease in developing countries has been made in the study by Goenka et al, 19 and in another study of Indian immigrants to the United Kingdom. 20 Other studies from the Middle East have reported similar findings. Various speculations have been made for this increase, among which are the Western lifestyle, variations in dietary intake, including refined sugar and chocolate, as well as environmental factors.…”

Section: Discussionsupporting

confidence: 57%

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Colonoscopy: Evaluating Indications and Diagnostic Yield

Al-Shamali

Kalaoui

Hasan

et al. 2001

Annals of Saudi Medicine

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Background: Colonoscopic procedure is an accepted modality for the evaluation of colonic disease. Open-access versus restricted-access colonoscopy has been argued over in the recent literature. The aim of this retrospective analysis is to identify the yield of the major indications for the procedure, and the pattern of colon pathology in our community. Patients and Methods:We retrospectively analyzed our experience in 3000 colonoscopies over a five-year period. The patients comprised 1145 females (38%) and 1855 males (62%), and their ages ranged from 9 months to 95 years (mean 39.2). There were 2283 patients (76%) who were aged less than 55 years. Complete examination to the cecum was possible in 2850 cases (95%). Results: Pathological findings were identified in 640 patients (21%). The diagnostic yield of patients referred for lower abdominal pain and surveillance was low, at 7% and 17%, respectively. The yield was high for those with lower gastrointestinal bleeding (47%), non-bloody diarrhea (35%), iron deficiency anemia (30%), mass lesions identified by radiology (53%), and polyps identified by radiology (70%). Inflammatory bowel disease was diagnosed in 220 patients, carcinoma in 64 patients, and colonic polyps in 139 patients. Conclusion: Colonic diseases are not uncommon in our part of the world. Colonoscopy is a rewarding procedure in those patients referred with lower gastrointestinal bleeding, mass lesions, polyps and diarrhea. The procedure is less rewarding in patients with lower abdominal pain and in those undergoing surveillance colonoscopy. Patient selection on the basis of the presenting complaint may help to utilize the limited resources available to gastroenterologists. About 63% of the procedures were done for indications found to have a low yield. Inflammatory bowel disease is seen with increasing frequency in our population.

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Section: Discussionsupporting

confidence: 57%

“…Inflammatory bowel disease patients are of mild-tomoderate severity. 4,5,20 Only a few patients had severe disease from the beginning, requiring occasional surgical intervention. Recurrence of colonic carcinoma was seen in 13 patients sent for surveillance.…”

Section: Discussionmentioning

confidence: 99%

Colonoscopy: Evaluating Indications and Diagnostic Yield

Al-Shamali

Kalaoui

Hasan

et al. 2001

Annals of Saudi Medicine

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“…Studies on epidemiology of IBD done on the Indian diaspora in Britain have clearly shown that Sikhs have a higher incidence (16.5/100,000 person-years) vis a vis other ethnic/religious groups such as Hindu (10.8/100,000 person-years) or Muslim (1.8/100,000 person-years). 11,12 Hence the prevalence figures obtained in these studies may not be a true reflection of the disease burden of the whole country. Niriella et al 10 determined the incidence of UC in Sri Lanka to be 0.69/100,000 person-years.…”

Section: Prevalence and Incidence Of Ulcerative Colitis In South Asiamentioning

confidence: 87%

“…The time trends suggest that the incidence of UC has been steadily rising among Asian migrants from 1981-1994. Probert et al 11 documented the incidence and prevalence of UC in South Asians to be 13.9/100,000 person-years and 172.5 respectively in the period between 1981-1989. In the period between 1991-1994 the incidence increased from 13.9 to 17.2 in the same geographical region.…”

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confidence: 99%

Epidemiology of Ulcerative Colitis in South Asia

Puri

2013

Intest Res

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“…The marked increase of IBD incidence in many countries in recent decades is incompatible with a purely genetic disease [1][2][3]. Also, data from migration studies indicate that second-generation immigrants manifest the risks of their new environment [4]. Established IBD risk factors include smoking, appendicitis, and antibiotics.…”

mentioning

confidence: 99%