Epidemiological study of the prevalence of allergic reactions to Hymenoptera in a rural population in the Mediterranean area

Fernández, J.; Blanca, Miguel; Soriano, Vincent; Sánchez, Jesús; Juárez, C.

doi:10.1046/j.1365-2222.1999.00614.x

Cited by 74 publications

(55 citation statements)

References 28 publications

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“…[8][9][10][11][12][13][14][15] While analyzing the data obtained from the latter investigations, it is important to consider gender in the context of other factors affecting the incidence of HVA, reflecting the degree of exposition, such as: age (child/adult), place of residence (industrialized/ rural areas), and sting rate (rarely/frequently).…”

Section: Gender and The Prevalence Of Insect Hypersensitivity Reactionsmentioning

confidence: 99%

“…[9][10][11][12][13] Comparable results estimating the prevalence of HVA as relatively equal were presented by three Spanish studies and a Polish one, performed on large populations living in industrialized urban areas of Europe. [8][9][10][11] Since the European investigations were conducted in one type of environment -industrial agglomerationstheir results seem to be clinically valid as the degree of exposition to stinging insects should be the same for women and men.…”

Section: Gender and The Prevalence Of Insect Hypersensitivity Reactionsmentioning

confidence: 99%

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Sex-related clinical aspects in insect venom anaphylaxis

Nittner-Marszalska

Liebhart

Dor-Wojnarowska

2015

Int J Immunopathol Pharmacol

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Experimental studies, epidemiological data, and clinical observations suggest that the gender factor is involved in the development and manifestation of IgE-dependent allergic diseases. We intend to answer the question if sex-related factors may play a role in Hymenoptera venom allergy (HVA). In the majority of recent studies the frequency of HVA symptoms with respect to both LL and SYS reactions is similar for men and women, while proven sensitization to insect venom is less frequent in women. Studies assessing clinical reactivity in HVA indicate that male sex and vespid venom allergy are factors increasing the risk of severe allergic reactions. Regarding the risk of adverse events associated with gender in the course of venom immunotherapy (VIT), the results of two large EAACI multicenter studies are discordant. In the first study, women showed increased risk of VIT adverse events. In the latter, systemic allergic side effects were not associated with gender. Despite theoretical premises and certain clinical observations indicating an important role of estrogens in allergic diseases, their influence on stinging insects' venom hypersensitivity is not unequivocal and remains still open. Further studies on the safety of VIT in females seem to be advisable.

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Section: Gender and The Prevalence Of Insect Hypersensitivity Reactionsmentioning

confidence: 99%

Section: Gender and The Prevalence Of Insect Hypersensitivity Reactionsmentioning

confidence: 99%

Sex-related clinical aspects in insect venom anaphylaxis

Nittner-Marszalska

Liebhart

Dor-Wojnarowska

2015

Int J Immunopathol Pharmacol

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“…Bu sebeple, nedeni belirlenemeyen ölümlerde arı veya ateş karıncası gibi böcek sokmalarının araştırılması önerilmektedir 2 . Epidemiyolojik çalışmalarda, arı sokmalarında alerjik reaksiyon riski %2,8-%28,7 arasında değişmektedir [3][4][5] . On altı -65 yaş grubunda yaşam boyu kümülatif arı sokma oranları %61-95 arasındadır.…”

Section: Gi Riflunclassified

Mersin Yöresinde Hymenoptera Venom Duyarlılık Oranları

...

2012

Turkderm

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ÖzetAmaç: Arı venomlarına karşı gelişen alerjik reaksiyonlar ciddi sonuçlarının olması nedeniyle önemli bir sağlık sorunu oluşturmaktadır. Bu çalışmayı, arı alerjisinin dolaylı bir ölçüsü olan duyarlılaşma oranlarının, Mersin yöresindeki durumunu belirlemek amacıyla yaptık. Gereç ve Yöntem: Yaş ortalamaları 38,4 yıl olan 86 erkek ve 123 kadın olmak üzere 209 gönüllüde, sorgulama, nefelometrik yöntemle total IgE, fluoroimmünoassay yöntemi ile fadiotop ölçümleri ile beraber, apidae, vespidae ve polistes venomlarına karşı epidermal/intradermal test uygulayarak duyarlılaşma oranlarını araştırdık. Bulgular: İki yüz dokuz olguda her üç venom türüne karşı duyarlılaşma oranını %21 bulduk. Venom duyarlılığı olan kişiler arasında birden çok venoma karşı duyarlı olanların oranı %52,3 idi. Sorgulama sonucunda, arı sokması ile oluşan reaksiyonların, %80'inin normal reaksiyon, %11'inin geniş lokal reaksiyon, %9'unun sistemik reaksiyon olduğu bulundu. Geniş lokal reaksiyon tarif eden olguların %23,5'unda, sistemik reaksiyon tarif eden olguların %21,5'inde deri testi pozitif idi. Erkeklerle kadınlar arasında; stratifiye edilen yaş grupları arasında; total IgE pozitif ve negatif olanlar arasında; Phadiotop pozitifliği olanlar ve olmayanlar arasında; kırsal ve kentsel bölgede oturanlar arasında; arı sokma sayısı bakımından; son arı sokmasından itibaren geçen zaman açısından ve reaksiyon türleri bakımından duyarlılaşma oranları arasında fark bulunmadı. Sonuç: Mersin yöresinde arı venomlarına karşı duyarlılık oranının oldukça yüksek olduğu, ama duyarlılaşma titrasyonunun düşük düzeyde olduğu; dolayısıyla arı venom alerjisinin önemli bir sağlık sorunu olabileceği görülmektedir. (Türk derm 2012; 46: 196-201) Anah tar Ke li me ler: Alerji, atopi, hymenoptera venom duyarlılığı, deri testi Sum maryBackground and Design: Allergic reactions to Hymenoptera venoms are significant health problems because of their serious outcomes. The aim of this study was to investigate the sensitization rates of Hymenoptera venoms (an indirect measure of Hymenoptera venom allergy) in Mersin region. Materials and Methods:In this study, we investigated the sensitization rates among 209 volunteers (86 males, 123 females, mean age: 38.4 years) using questionnaires, total IgE determination with nephelometric method and phadiotop determinations with fluoroimmunoassay, epidermal/intradermal testing with Apidae, Vespidae and Polistes venom extracts. Results: Sensitization rate to venoms of all three species were 21.0% among 209 subjects. Sensitization rate to more than one species simultaneously was 52.3% among Hymenoptera-sensitive subjects. With the aid of questionnaires we found that sting reactions were "normal reactions" in 80%, "large local reactions" in 11.0% and "systemic reactions" in 9% of the subjects. The rate of positive skin tests was 23.5% among the subjects who described large local reactions and 21.5% among the subjects who described systemic reactions. There were no significant difference in the sensitization rates between males and females, in...

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“…Systemic reactions (SR) due to hymenoptera venom allergy affect between 2.3% and 2.8% of the rural population in Spain [1] and may lead to potentially life-threatening anaphylaxis.…”

Section: Introductionmentioning

confidence: 99%

Key Issues in Hymenoptera Venom Allergy: An Update

Alfaya

Soriano-Gomis

Mera

et al. 2017

J Investig Allergol Clin Immunol

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In this review, the Hymenoptera Allergy Committee of the SEAIC analyzes the most recent scientific literature addressing problems related to the diagnosis of hymenoptera allergy and to management of venom immunotherapy. Molecular diagnosis and molecular risk profiles are the key areas addressed. The appearance of new species of hymenoptera that are potentially allergenic in Spain and the associated diagnostic and therapeutic problems are also described. Finally, we analyze the issue of mast cell activation syndrome closely related to hymenoptera allergy, which has become a new diagnostic challenge for allergists given its high prevalence in patients with venom anaphylaxis.

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Epidemiological study of the prevalence of allergic reactions to Hymenoptera in a rural population in the Mediterranean area

Cited by 74 publications

References 28 publications

Sex-related clinical aspects in insect venom anaphylaxis

Sex-related clinical aspects in insect venom anaphylaxis

Mersin Yöresinde Hymenoptera Venom Duyarlılık Oranları

Key Issues in Hymenoptera Venom Allergy: An Update

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