Epidemiological study of soft‐tissue sarcomas in Ireland

Bhatt, Nikita; Deady, Sandra; Gillis, Amy; Bertuzzi, Alexia; Fabre, Aurélie; Heffernan, Eric J.; Gillham, Charles; O’Toole, Gary; Ridgway, Paul F.

doi:10.1002/cam4.547

Cited by 11 publications

(13 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The overall 5-year survival rate of the STS patient cohort after diagnosis was 56.4%, which was similar to that reported by other countries: Ireland (56%, 1994-2011) [20] and the United Kingdom (55%, 2006-2010) [21]; close to the European average (57.8%, 2000-2002) [6] but lower than in the United States (65%, 2006-2012) [25] and Japan (77.5%, 2006-2012) [15]. It should be noted that the Japanese study reported disease-specific survival rates.…”

Section: Discussionsupporting

confidence: 85%

“…The total incidence of STS in our analyses of Korea (2.49 per 100,000 person-years) is within the reported incidences. The incidence is lower when compared with the incidence rates of some countries or regions, for example the United States (4.2 per 100,000 person-years) [19], Europe (4.7 per 100,000 person-years) [6], Ireland (4.48 per 100,000 person-years) [20] and the United Kingdom (4.51 per 100,000 person-years) [21]. However, the incidence is higher than the incidence rate reported for Sweden (1.8 per 100,000 person-years) [22] and Beijing (1.15 per 100,000 person-years) [23].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Characteristics and Treatment Patterns of Patients with Advanced Soft Tissue Sarcoma in Korea

et al. 2019

View full text Add to dashboard Cite

PurposeA soft tissue sarcoma (STS) is a rare type of cancer, accounting for 1% of adult solid cancers. The aim of the present study is to determine the incidence of localized and advanced STS in Korean patients, their treatment patterns, and the survival of patients by disease status.Materials and MethodsThe STS patient cohort was defined using National Health Insurance Service medical data from 2002 to 2015. Incidence, distribution, anatomical location of tumors, survival rates (Kaplan-Meyer survival function) and treatment patterns were analyzed by applying different algorithms to the STS cohort containing localized and advanced STS cases.ResultsA total of 7,813 patients were diagnosed with STS from 2007 to 2014, 4,307 were localized STS and 3,506 advanced STS cases. The total incidence of STS was 2.49 per 100,000 person- years: 1.37 per 100,000 person-years for localized STS and 1.12 per 100,000 person-years for advanced STS. The 5-year survival rate after diagnosis was 56.4% for all STS, 82.4% for localized, and 27.2% for advanced STS. Half of the advanced STS patients (49.98%) received anthracycline-containing chemotherapy as initial treatment after diagnosis.ConclusionThis study provides insights into localized and advanced STS epidemiology, treatment patterns and outcomes in Korea, which could be used as fundamental data in improving clinical outcomes of STS patients in the future.

show abstract

Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Characteristics and Treatment Patterns of Patients with Advanced Soft Tissue Sarcoma in Korea

et al. 2019

View full text Add to dashboard Cite

show abstract

“…However, the peak age of STS in Beijing was 80-84 years old [6], which may be related to the grouping method. The peak age of patients with STS initiated in extremities in Korea from 2009 to 2011 was 70-89 years old [12], and the peak age of STS patients in Ireland from 1994 to 2012 was 70-84 years old [13], which were different from the results in our study. The reason may be that the patients of STS only in extremities were analyzed in Korea, but not in the whole body excluding visceral sarcoma; and the research in Ireland was about the STS in whole body including visceral sarcoma.…”

Section: Discussioncontrasting

confidence: 99%

Epidemiology of patients with musculoskeletal soft tissue sarcomas in a cancer hospital in Central China: A study of 1624 cases.

Zhang

Liu

Feng

et al. 2020

Preprint

View full text Add to dashboard Cite

Background : To analyze the incidence characteristics of 1624 inpatients with soft tissue sarcoma (STS) during 2006 to 2016 in Henan Province Cancer Hospital in Central China. Methods : The information of electronic medical record from the first hospitalized patients with STS in Henan Province Cancer Hospital during January 1, 2006 to December 31, 2016 was collected, and descriptive statistics was analyzed on age, gender, pathological type and tumor location by using SPSS21.0 software. Results : There were 1624 inpatients with STS in Henan Province Cancer Hospital in 2006~2016.The top nine pathological subtypes of STS with high constituent ratio were undifferentiated pleomorphic sarcoma (UPS,23.83%),synovial sarcoma(16.69%), liposarcoma(13.67%), fibrosarcoma(10.22%), sarcoma without definite type (8.99%), leiomyosarcoma(7.02%), dermatofibrosarcoma protuberant (5.79%),rhabdomyosarcoma (4.68%) and malignant neurilemmoma(4.25%). The average age of inpatients was 44.71±17.91, and the inpatients aged 35-64 accounted for 56.34%.The number of UPS inpatients reached the peak at the age of 45 to 59; The median age of inpatients with rhabdomyosarcoma was 17 year.In total 1624 inpatients of STS, the number of male and female inpatients were 923 and 701, respectively. The gender ratio was 1.32:1. The proportion of UPS in either male or female inpatients was the highest, accounting for 23.07% and 24.82%, respectively. The number of male inpatients was more than that of female in the top nine pathological subtypes of STS except leiomyosarcoma (the gender ratio was 0.84:1). The most common initiation location of UPS, synovial sarcoma, liposarcoma was lower extremity, accounting for 51.16%, 53.13% and 52.25% in corresponding pathological type group, respectively. Dermatofibrosarcoma protuberant, rhabdomyosarcoma and fibrosarcoma were all mainly initiated in trunk, accounting for 72.34%, 47.83% and 45.57% , respectively. Leiomyosarcoma tend to occur in retroperitoneum. Conclusion : The top three pathological subtypes of STS with high constituent ratio were UPS, synovial sarcoma and liposarcoma.UPS should be paid more attention on the prevention, treatment and research in Henan province in future for its highest proportion of STS.

show abstract

“…The lower peak age in the study may be related to it including embryonal rhabdomyosarcoma with the lower age of onset. The peak age of STS of the extremities in Korea from 2009 to 2011 was 70-89 years old [13], and the peak age of STS in Ireland from 1994 to 2012 was 70-84 years old [14], which were different from the results of the study. The reason may be that the result in Korea mainly studies STS of the extremities, but not the whole body (excluding visceral sarcoma), and the research in Ireland was about the whole body including visceral sarcoma.…”

Section: Discussionmentioning

confidence: 59%

The analysis of characteristics of 1624 soft tissue sarcoma cases in 2006~2016 in Henan Province Cancer Hospital, China

Zhang

Liu

Zhang

et al. 2019

Preprint

View full text Add to dashboard Cite

Background To analyze the incidence characteristics of 1624 inpatients with soft tissue sarcoma (STS) during 2006 to 2016 in Henan Province Cancer Hospital.Methods The information of electronic medical record from the first hospitalized patients with STS in Henan Province Cancer Hospital during January 1, 2006 to December 31, 2016 was collected, and descriptive statistics was analyzed on age, gender and pathological type by using SPSS21.0 software.Results There were 1624 inpatients with STS in Henan Province Cancer Hospital in 2006~2016.The top nine pathological subtypes of STS with high constituent ratio were undifferentiated pleomorphic sarcoma (UPS,23.83%),synovial sarcoma(16.69%), liposarcoma(13.67%), fibrosarcoma(10.22%), sarcoma without definite type (8.99%), leiomyosarcoma(7.02%), dermatofibrosarcoma protuberant (5.79%),rhabdomyosarcoma (4.68%) and malignant peripheral nerve sheath tumor(4.25%). The average age of inpatients was 44.71±17.91, and the inpatients aged 35-59 accounted for 47.6%.The number of UPS inpatients reached the peak at the age of 55 to 64; The proportion of rhabdomyosarcoma between 0~4 and 5~9 years old can reach above 46%.In total 1624 inpatients of STS, the number of male and female inpatients were 923 and 701, respectively. The gender ratio was 1.32:1. The proportion of UPS in either male or female inpatients was the highest, accounting for 23.10% and 24.80%, respectively. The number of male inpatients was more than that of female in the top nine pathological subtypes of STS except leiomyosarcoma (the gender ratio was 0.84:1).Conclusion The top three pathological subtypes of STS with high constituent ratio were UPS, synovial sarcoma and liposarcoma.UPS should be paid more attention on the prevention, treatment and research in Henan in future for its highest proportion of STS.

show abstract

Epidemiological study of soft‐tissue sarcomas in Ireland

Cited by 11 publications

References 10 publications

Characteristics and Treatment Patterns of Patients with Advanced Soft Tissue Sarcoma in Korea

Characteristics and Treatment Patterns of Patients with Advanced Soft Tissue Sarcoma in Korea

Epidemiology of patients with musculoskeletal soft tissue sarcomas in a cancer hospital in Central China: A study of 1624 cases.

The analysis of characteristics of 1624 soft tissue sarcoma cases in 2006~2016 in Henan Province Cancer Hospital, China

Contact Info

Product

Resources

About