Epidemiological profile, temporal trend and geographic location of the occurrence of meningitis in Alagoas (2008-2017)

Abstract

Background: Meningitis is a neuroinfection of multivariate etiologies, high morbidity and mortality and social impact. Objectives: To describe the epidemiological profile and analyze the trend and spatial distribution of meningitis in the state of Alagoas, Brazil, in the period 2008-2017. Methods: The ecological study is based on confirmed processes of meningitis and deaths from disease. Data were collected from the National Notification System. Clinical and epidemiological variables were analyzed, such as incidence and mortality rates. The regression model was used as a regression model for inflection points. A spatial sample was performed by a local empirical model, followed by global and local Moran statistics. Confidence interval of 95% and significance of 5% were considered. Results: 1365 cases were reported to Alagoas state, 59.6% male, 60.7% aged up to 19 years and 89.8% brown. Regarding the clinical profile, standing out: bacterial meningitis (24.3%), serum group Y (14.0%) and diagnosis by chemocytology (32.7%). Inflation decreased from 4.97/100 thousand in 2008 to 3.23/100 thousand in 2017 (AAPC -7.3%; p <0.001). Growth rate in growing trend from 10.3% in 2008 to 15.85% in 2017 (AAPC 4.7%; p <0.001). The capital city of Maceió presented a greater exchange of notified cases (40.7%). The highest incidence rates are those of Marechal Deodoro (36.00 / 100 thousand) and Maragogi (29.63/100 thousand). The priority municipalities were in the eastern region. Conclusions: The study showed a reduction in the incidence of Meningitis and heterogeneous spatial distribution in the state of Alagoas.