Epidemiological investigations into multiple sclerosis in Southern Hesse. V. Course and prognosis

Lauer, Klaus; Firnhaber, W

doi:10.1111/j.1600-0404.1987.tb03537.x

Cited by 29 publications

(15 citation statements)

References 16 publications

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“…In line with our results, previously published data indicate that an RR course of MS is strongly correlated with a better prognosis, whereas the prognosis seems to be poorer for both an SP and PP course [4,6,24,25]. In some previous studies, the prognosis was found to be favourable when only one functional system was affected [26,27]. Our results are in accordance with these findings.…”

Section: Discussionsupporting

confidence: 83%

Survival of Multiple Sclerosis Patients in the Belgrade Population

Pekmezović

Jarebinski²,

Drulović³

et al. 2002

Neuroepidemiology

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The aim of this study was to estimate survival rates of multiple sclerosis (MS) patients in the Belgrade population, Yugoslavia, and furthermore, to determine the prognostic value of some demographic and clinical variables for survival. The cumulative survival probability was calculated by the Kaplan-Meier method. The prognostic value of different variables was assessed by univariate and multivariate analyses using the Cox regression model. In the Belgrade population, the cumulative 25-year survival probability of MS patients and the mean survival time from MS onset were 73.2% and 38 years, respectively. The univariate analysis showed that survival was significantly related to sex, age at onset, course of disease and monoregional initial symptoms. A multivariate model demonstrated that a relapsing-remitting course of MS and monoregional onset were predictors of a better prognosis. The presence of motor symptoms at the onset was found to be an independent predictor of a poorer outcome of MS.

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Section: Discussionsupporting

confidence: 83%

Survival of Multiple Sclerosis Patients in the Belgrade Population

Pekmezović

Jarebinski²,

Drulović³

et al. 2002

Neuroepidemiology

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“…CIS patients presenting with motor symptoms have a risk of secondary progression 2.0 times higher and a risk of being wheelchair-bound after 25 years 2.8 times higher than patients with purely sensory symptoms (Eriksson et al, 2003). Similarly, patients with motor, sphincter, cerebellar, spinal cord, or multiregional involvement at onset have also been reported to have worse outcomes than patients without these features (Lauer and Firnhaber, 1987;Phadke, 1990;Bergamaschi et al, 2005;Ebers, 2005).…”

Section: Disabilitymentioning

confidence: 94%

Early prognosis of multiple sclerosis

Swanton¹,

Fernando²,

Miller³

2014

Handbook of Clinical Neurology

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“…8,15,34 ONS data have been used to estimate the increase in mean age at death from MS since the 1950s. The data are presented in Figure 6.…”

Section: Estimates Of Changes In Prevalence With Timementioning

confidence: 99%

A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models

Richards

Sampson

Beard

et al. 2002

Health Technol Assess

131

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Epidemiological investigations into multiple sclerosis in Southern Hesse. V. Course and prognosis

Cited by 29 publications

References 16 publications

Survival of Multiple Sclerosis Patients in the Belgrade Population

Survival of Multiple Sclerosis Patients in the Belgrade Population

Early prognosis of multiple sclerosis

A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models

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