Epidemiological features of irritable bowel syndrome in a Turkish urban society

Çelebi, Selman; Açik, Yasemin; Deveci, Süleyman Erhan; Bahçecıoğlu, İbrahim Halil; Ayar, Ahmet; Demır, Ali; Durukan, Polat

doi:10.1111/j.1440-1746.2004.03367.x

Cited by 57 publications

(49 citation statements)

References 41 publications

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“…The prevalence of IBS and other functional gastrointestinal disorders found in the presented study is very similar to that previously reported [17, 18]. Of the 5 participants who had dark blood mixed in their stools, 4 had amebic colitis diagnosed microbiologically and pathologically.…”

Section: Discussionsupporting

confidence: 90%

Prevalence and Consultation Behavior of Self-Reported Rectal Bleeding by Face-to-Face Interview in an Asian Community

et al. 2008

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Background and Aim: Although rectal bleeding is a common gastrointestinal symptom, there are very few community-based studies, and all of these studies were conducted in the West. So far the epidemiologic characteristics of rectal bleeding have not been defined in an Asian country. We aimed to characterize self-reported rectal bleeding and its association with functional bowel disorders in Turkey. Factors affecting healthcare-seeking behavior were reviewed as well. Subjects and Methods: In this study, 760 subjects were chosen randomly. Questionnaires were completed by nurses during face-to-face interviews with each participant. Results: Of the 707 (93%) subjects included in this study, 9.5% had functional dyspepsia, 8.6% had irritable bowel syndrome (IBS), 24.5% had functional constipation, and 13.8% had functional abdominal bloating. The prevalence of rectal bleeding in the previous year was 14.7%. The recent onset of rectal bleeding was 2.7%. Rectal bleeding was more common among subjects younger than 45 years. Subjects who had functional constipation or constipation-dominant IBS reported rectal bleeding more frequently than others. The rate of consultation was only 41.3% among the subjects with rectal bleeding. Subjects aged ≧45 years and who had marked bleeding or bleeding more than twice a day or fear of cancer sought healthcare more frequently than others. Conclusion: Rectal bleeding is as common a symptom in Turkey as in Western countries. Advanced age and fear of cancer were independent predictors of consultation behavior in this group.

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Section: Discussionsupporting

confidence: 90%

Prevalence and Consultation Behavior of Self-Reported Rectal Bleeding by Face-to-Face Interview in an Asian Community

et al. 2008

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“…The genetic predisposition to FBD is unknown, but under investigation globally. The infl uence of multiple episodes of infectious diarrhea in the 'non-sterile' environment of developing nations is unknown [13] . In addition, the inherent 'urban stress' from living in one of the most populated cities in the world is likely operative.…”

Section: Discussionmentioning

confidence: 99%

Frequency of Functional Bowel Disorders among Healthy Volunteers in Mexico City

Schmulson¹,

Ortiz²,

Santiago-Lomeli³

et al. 2006

Dig Dis

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Background: The frequency of functional bowel disorders (FBD) in Mexico using the Rome II criteria is unknown. Methods: The Rome II Modular Questionnaire (RII-MQ) was translated into Spanish in coordination with the Rome Committee and their Latin American program. Volunteers were recruited by advertisement in Mexico City, and administered the RII-MQ. Results:The study population consisted of 324 healthy volunteers, with a mean age of 35.7; 66% were female. The most prevalent disorders were heartburn 35%, irritable bowel syndrome (IBS) 35%, functional bloating 21%, proctalgia fugax 21%, and functional constipation 19%. Based on gender, IBS-C was 4 times more frequent in females than males (19 vs. 4.6%) and functional bloating 3 times more frequent (10 vs. 3.7%). Differences according to occupation included a higher prevalence of ulcer-like dyspepsia (p = 0.04), IBS-C (p = 0.018) and proctalgia fugax (p = 0.034) among students. Conclusions: This is the first study to use RII-MQ to determine the prevalence of FBD in urban Mexico. The prevalence of IBS was significant and is related to a number of factors, including the stress of living in an overpopulated city. Selection bias is likely operative. A community-based study is warranted.

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“…The prevalence of IBS in Asia is reportedly 5-9% [2][3][4][5][6][7][8][9][10][11][12][13], while in Western countries it is 10-20% [14][15][16][17][18][19][20][21][22][23][24][25]. Furthermore, no female predominance was found in Asian IBS patients [2], in contrast to in Western IBS patients [22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

“…Abdominal bloating is a more common complaint than pain in Asians, and this abdominal pain is localized to the upper abdomen rather than in the lower abdomen like it is in Western patients. Moreover, alteration in bowel habits is much less prominent in Asian IBS patients than in Western patients [2][3][4][5][6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Chromogranin A cell density in the large intestine of Asian and European patients with irritable bowel syndrome

Patcharatrakul

Hatlebakk

Hausken

et al. 2017

Scandinavian Journal of Gastroenterology

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Objective: Patients with irritable bowel syndrome (IBS) in Asia show distinctive differences from those in the western world. The gastrointestinal endocrine cells appear to play an important role in the pathophysiology of IBS. The present study aimed at studying the density of chromogranin A (CgA) cells in the large intestine of Thai and Norwegian IBS patients. Methods: Thirty Thai IBS patients and 20 control subjects, and 47 Norwegian IBS patients and 20 control subjects were included. A standard colonoscopy was performed in both the patients and controls, and biopsy samples were taken from the colon and the rectum. The biopsy samples were stained with hematoxylin-eosin and immunostained for CgA. The density of CgA cells was determined by computerized image analysis. Results: In the colon and rectum, the CgA cell densities were far higher in both IBS and healthy Thai subjects than in Norwegians. The colonic CgA cell density was lower in Norwegian IBS patients than in controls, but did not differ between Thai IBS patients and controls. In the rectum, the CgA cell densities in both Thai and Norwegian patients did not differ from those of controls. Conclusions: The higher densities of CgA cells in Thai subjects than Norwegians may be explained by a higher exposure to infections at childhood and the development of a broad immune tolerance, by differences in the intestinal microbiota, and/or differing diet habits. The normal CgA cell density in Thai IBS patients in contrast to that of Norwegians may be due to differences in pathophysiology.ARTICLE HISTORY

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Epidemiological features of irritable bowel syndrome in a Turkish urban society

Abstract: Although IBS is widely present in Turkey, its prevalence is lower than that reported in Western communities. In the region where this study was carried out, IBS was more prevalent in females and in individuals with low educational and economical status.

Cited by 57 publications

References 41 publications

Prevalence and Consultation Behavior of Self-Reported Rectal Bleeding by Face-to-Face Interview in an Asian Community

Prevalence and Consultation Behavior of Self-Reported Rectal Bleeding by Face-to-Face Interview in an Asian Community

Frequency of Functional Bowel Disorders among Healthy Volunteers in Mexico City

Chromogranin A cell density in the large intestine of Asian and European patients with irritable bowel syndrome

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