Epidemiological features after emergency declaration in Hokkaido and report of 15 cases of COVID-19 including 3 cases requiring mechanical ventilation

Edagawa, Shunji; Kodama, Fumihiro; Takada, Masayuki; Itagaki, Yuki; Kodate, Akira; Bando, Keisuke; Sakurai, Keisuke; Endo, Ayana; Sageshima, Hisako; Nagasaka, Atsushi

doi:10.35772/ghm.2020.01024

Cited by 7 publications

(6 citation statements)

References 5 publications

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“…Therefore, WHO guidance proposed that systemic corticosteroids should be carefully used only in selected cases. In addition, some recent Japanese studies have reported that ciclesonide, as one type of ICS, may have positive effects in treating COVID-19 [ 21 , 22 ]. However, this study concludes that recent usage of asthma medication did not affect clinical outcomes of COVID-19, independently.…”

Section: Discussionmentioning

confidence: 99%

Effect of asthma and asthma medication on the prognosis of patients with COVID-19

et al. 2020

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BackgroundCoronavirus disease (COVID-19) has rapidly spread worldwide. However, the effects of asthma, asthma medication, and asthma severity on the clinical outcomes of COVID-19 have not yet been established.MethodsThe study included 7590 de-identified patients, who were confirmed to have COVID-19 using the severe acute respiratory syndrome-coronavirus-2 RNA–polymerase chain reaction tests conducted up to 15th May 2020; and we used the linked-medical claims data provided by the Health Insurance Review and Assessment Service. Asthma and asthma severity (step suggested by GINA) was defined using the diagnostic code and history of asthma medication usage.ResultsAmong 7590 COVID-19 patients, 218 (2.9%) had underlying asthma. The total medical cost associated with COVID-19 patients with underlying asthma was significantly higher than that of other patients. Mortality rate for COVID-19 patients with underlying asthma (7.8%) was significantly higher than that of other patients (2.8%; p<0.001). However, asthma was not an independent risk factor for the clinical outcomes of COVID-19 after adjustment. Asthma medication use and asthma severity also did not affect the clinical outcomes of COVID-19. However, use of oral short-acting β2-agonists (SABA) was an independent factor to increase the total medical cost burden. Patients with step 5 asthma showed significant prolonged admission duration than those with step 1 asthma in both univariate and multivariate analysis.ConclusionsAsthma led to poor outcomes of COVID-19; however, underlying asthma, use of asthma medication, and asthma severity were not independent factors for poor clinical outcomes of COVID-19, generally.

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Section: Discussionmentioning

confidence: 99%

Effect of asthma and asthma medication on the prognosis of patients with COVID-19

et al. 2020

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“…Since then, the number of reported cases has continued to increase and Hokkaido has become the most heavily impacted area in Japan. Taking the situation very seriously, the Hokkaido Government issued a "Declaration of State of Emergency in Hokkaido" on February 28, 2020 [4]. With a decrease in the number of reported cases, Hokkaido's declaration of a state of emergency was then lifted on March 19.…”

Section: Introductionmentioning

confidence: 99%

Rehabilitation Outcomes and Infection Control in the Early Stage of the COVID-19 Pandemic

Igawa

2021

SciMed. J.

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Introduction: Understanding how infection control measures were devised and the outcomes of rehabilitation in the early stage of an emerging infectious disease pandemic is important. This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on inpatient rehabilitation, and to determine the effectiveness of the original infection control measures implemented for the rehabilitation team. Material and Methods: In this single-center, retrospective, observational study, we calculated multiple rehabilitation indices of patients discharged from our rehabilitation ward between February 28 and May 25, 2020 when Hokkaido was initially affected by COVID-19, and compared them with those calculated during the same period in 2019. Fisher’s exact test and the Mann-Whitney U test were used for statistical analysis. We also verified the impact of implementing the original infection control measures for the rehabilitation team on preventing nosocomial infections. Results: A total of 93 patients (47 of 2020 group, 46 of 2019 group) were included. The median age was 87 and 88 years, respectively, with no differences in age, sex, and main disease between the groups. Training time per day in the ward in 2020 was significantly lower than that in 2019 (p = 0.013). No significant differences were found in the qualitative evaluation indices of Functional Independence Measure (FIM) score at admission, FIM gain, length of ward stay, FIM efficiency, and rate of discharge to home. None of the patients or staff members had confirmed COVID-19 during the study period. Conclusions: Early COVID-19 pandemic affected the quantitative index for inpatient rehabilitation but not the qualitative indices. No symptomatic nosocomial COVID-19 infections were observed with our infection control measures. Doi: 10.28991/SciMedJ-2021-03-SI-6 Full Text: PDF

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“…1 The Japanese public health agencies found clustering in the “Three Cs”: closed spaces with poor ventilation, crowded spaces with many people, and close contact 2 ; however, the clinical investigation of Japanese patients with COVID‐19 is limited. 3 , 4 , 5 , 6 , 7 Besides, no study has existed evaluating COVID‐19 in outpatient settings although understanding COVID‐19 is crucial for frontline clinical practitioners. We aimed to describe and compare the demographic, clinical, and epidemiological characteristics and outcomes of patients with and without COVID‐19 who presented to the Teine Keijinkai Medical Center Infection Triage Clinic, Sapporo, Japan.…”

Section: Introductionmentioning

confidence: 99%

A single‐center comparative analysis of outpatients with and without COVID‐19 in Sapporo, Japan

Shimamura

Masuda

Anbo

et al. 2021

J of Gen and Family Med

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This study aimed to investigate the demographic, clinical, and epidemiological statistics of Japanese patients attending a designated outpatient clinic for COVID‐19 in Sapporo, Japan, and contrast the clinical and epidemiological features between those with and without mild COVID‐19. A total of 27 (8.6%) of 315 patients were diagnosed with COVID‐19. They had higher proportions of myalgia, direct contact with a confirmed COVID‐19 patient, and attendance of social gatherings in close confines. We believe that our study makes a significant contribution to the literature because it provides a clinical picture of mild COVID‐19 in the Japanese population, which has not been studied extensively. It can also assist in optimizing the local preventive measures to reduce the transmission of COVID‐19.

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Epidemiological features after emergency declaration in Hokkaido and report of 15 cases of COVID-19 including 3 cases requiring mechanical ventilation

Cited by 7 publications

References 5 publications

Effect of asthma and asthma medication on the prognosis of patients with COVID-19

Effect of asthma and asthma medication on the prognosis of patients with COVID-19

Rehabilitation Outcomes and Infection Control in the Early Stage of the COVID-19 Pandemic

A single‐center comparative analysis of outpatients with and without COVID‐19 in Sapporo, Japan

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