Epidemiological evaluation of rubella virus infection among pregnant women in Ibadan, Nigeria

Abstract

Rubella is a vaccine-preventable, mild rash-inducing viral disease with complications that include a spectrum of birth defects in the developing foetus, especially if the infection is acquired in the early months of pregnancy. Consequently, the primary objective of global rubella control programmes is prevention of congenital rubella infection and associated birth defects often collectively referred to as congenital rubella syndrome.Despite the availability of safe and effective vaccines, and elimination of rubella virus in many developed countries substantial commitment to rubella control has not been demonstrated in the developing countries. This study appraises immunity to rubella, and consequently makes appropriate recommendations aimed at facilitating effective control.A cross-sectional sero-surveillance study was carried out among 272 consenting ante-natal