Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms

Abstract

To cite: Jin X, lian J-s, hu Jh, et al. Gut epub ahead of print: [please include Day Month Year].

Alerta: los síntomas gastrointestinales podrían ser una manifestación de la COVID-19

“…A total of 15 papers that analyzed the clinical experience with the COVID-19 infection that also reported the presence of gastrointestinal symptoms, were identified. [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Thirteen papers were from China, 5-13, 15-17, 19 one from Singapore, 18 and one from the World Health Organization European Region. 14 (Table 1) These papers analyzed a total of 2800 patients.…”

“…And in the majority of the cases, was self-limited. 10 In terms of epidemiological factors related to the presence of GI symptoms, Chen N et al, reported that 49% of their 99 patients had a history of exposure to the Huanan seafood market, from where the first cases of COVID-19 appeared to raise. 6 However, they did not report if this epidemiological factor was related or not with the presence of gastrointestinal symptoms or any other clinical manifestation.…”

“…9 In the previously mentioned Zhejiang study, the history of presence in Wuhan or contact with other patients with COVID-19, was not different among patients with or without GI symptoms, however family clustering was significantly higher among patients with those symptoms. 10 In relation to the patients prognosis according to the presence or not of GI symptoms, Wang D et al compared the frequency of gastrointestinal symptoms between patients hospitalized in the intensive care unit (ICU) or not, without finding any difference, except for abdominal pain that was more common in the first ones (8.3% vs 0, p=0.02). 15 In agreement with this finding, among the first 18 hospitalized patients with transcriptase-polymerase chain reaction (RT-PCR)-confirmed SARS-CoV-2 in Singapore, three patients reported diarrhea, and none of them required supplemental oxygen.…”

Facing COVID-19 in the hematopoietic cell transplant setting: A new challenge for transplantation physicians

“…in addition to COVID-19. Regarding the gastrointestinal symptoms, we now have enough data mentioning gastrointestinal (GI) symptoms like diarrhea, nausea, and vomiting as presenting symptoms for COVID-19 disease [5]. This GI symptomatology of COVID-19 can easily be confused with other differentials like acute graft-versus-host disease, CMV colitis, mucositis, etc.…”

Respuesta de autores a: A propósito de la carta científica «Sospecha de abdomen agudo como manifestación extrapulmonar de infección COVID-19»

“…(1) De esta manera, en época de pandemia por COVID-19, como cirujanos quedamos expuestos sin la protección adecuada ante pacientes que se presenten en urgencias con cuadros gastrointestinales de COVID-19 y leves o ningún síntoma pulmonar; hasta un 10% presentan radiografías de tórax sin neumonía como en el caso expuesto. (2) Consideramos que deberían replantearse los protocolos y nos cuestionamos si los tests de entrada masivos hubieran permitido un mejor triaje y tratamiento de los pacientes atendidos desde urgencias, evitando que se extendiera la infección. Ante la sospecha por el contexto epidemiológico, hay datos que se han expuesto en el caso que nos ayudaron a pensar en la posibilidad de COVID-19 y que su inmediatez permite avanzar en el diagnóstico y aislamiento del paciente.…”