Epidemiological characteristics of H1N1 positive deaths: A study from tertiary care hospital in western India

Taklikar, Chandrashekhar; Nanaware, Mangesh

doi:10.5455/ijmsph.2013.2.303-306

Cited by 5 publications

(7 citation statements)

References 7 publications

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“…Positivity and mortality were predominantly seen in 16-65 yr age group in the present study as has been earlier reported from India and other countries 16 17 23 24 25 . People in this age group are mostly working and thus liable to get exposed to pandemic influenza A (H1N1) 2009 infection while those above 65 yr may have had greater immunity due to previous exposure to similar viruses 26 27 .…”

Section: Discussionsupporting

confidence: 87%

“…A study from the USA reported co-morbidities in 73 per cent of fatal cases; asthma, diabetes, heart, lung, neurologic diseases and pregnancy 28 ; in addition, metabolic diseases, immunosuppressive conditions and neuromuscular disorders were reported from California 25 . Heart and respiratory diseases along with anaemia, obesity and cancer were the common co-morbidities reported in Indian studies 20 23 . High mortality was found in pregnant women in our study as reported earlier 3 22 .…”

Section: Discussionmentioning

confidence: 99%

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Epidemiological & clinical profile of influenza A (H1N1) 2009 virus infections during 2015 epidemic in Rajasthan

Malhotra

Singh²,

Sharma

et al. 2016

Indian J Med Res

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Background & objectives:Pandemic influenza A (H1N1) 2009 virus emerged in 2009 and caused pandemic with high morbidity and mortality in India and worldwide. The number of H1N1-positive cases varied in different years in Rajasthan. The objective of the study was to present the epidemiological profile of pandemic influenza A (H1N1) 2009 virus cases in Rajasthan from January to March 2015.Methods:A retrospective descriptive, record-based analysis of suspected and confirmed cases of pandemic influenza A (H1N1) 2009 virus infection in Rajasthan, India, from January to March 2015 was performed. Testing was done as per the Centers for Disease Control guidelines at nine laboratories approved by the Government of Rajasthan. Data were analyzed in terms of demographic characteristics, clinical presentation and outcome.Results:Among 18,187 tested cases, 6203 (34.10%) were positive. Death occurred in 378 cases, with six per cent case fatality rate. Maximum number of cases (n=2801) and deaths (n=101) were from Jaipur zone. The highest number of cases, 47.60 per cent (2953/6203) and deaths, 52.11 per cent (197/378) were in the age group of 26-50 yr; 52.64 per cent (199/378) of deaths occurred in females. The highest number (63.5%) of deaths was from urban areas. Associated risk factors were observed in 59.44 per cent of the death cases, pregnancy being the predominant predisposing factor. In 61.92 per cent of patients, death occurred within three days of hospitalization.Interpretation & conclusions:H1N1 epidemic caused high morbidity and mortality in early 2015, particularly in the younger and middle-aged population and pregnant women in Rajasthan State of India. The study highlights the regular surveillance of influenza like illness, early diagnosis and timely initiation of therapy in suspected cases.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Epidemiological & clinical profile of influenza A (H1N1) 2009 virus infections during 2015 epidemic in Rajasthan

Malhotra

Singh²,

Sharma

et al. 2016

Indian J Med Res

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“…Positivity were predominantly seen 21-60 yrs age group in the present study as has been earlier reported from India and other countries Singh et al, 2013;Taklikar and Nanaware, 2013;Pebody et al, 2009;Louie et al, 2009). People in this age group are mostly working and thus liable to get exposed to pandemic influenza A (H1N1) 2009 infection while those above 60 yrs may have had greater immunity due to previous exposure to similar viruses (Itolikar and Nadkar, 2015;Dawood et al, 2012).…”

Section: Methodssupporting

confidence: 72%

“…4). Diabetes, heart and respiratory diseases along with anaemia, obesity and cancer were the common co-morbidities reported in Indian and Californian studies (Puvanalingam et al, 2011;Taklikar and Nanaware, 2013).…”

Section: Methodsmentioning

confidence: 99%

An Experience of Pandemic Influenza A (H1N1) 2009 Virus Outbreak in 2017 at Tertiary Care Hospital, Chennai, Tamilnadu, India

Thilakavathi¹,

Rosyvennila²

2018

Int.J.Curr.Microbiol.App.Sci

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“…More than 50% patients needed mechanical ventilation and these were those who had presented to the hospital after 48 hours. Presence of co-morbid conditions is another risk factor associated with poor maternal and neonatal outcome as shown by many national [21,22,23,24] and international studies [25,26] . Bronchial asthma [27] is commonest co-morbid condition seen in these patients but in our study anemia complicated the course as it is a tertiary care center in a rural area.…”

Section: Discussionmentioning

confidence: 99%

A retrospective study of critically-ill pregnant women with H1N1 infection in a tertiary care rural medical college of Gujarat

Sapre¹,

Raithatha²,

Bhattacharjee³

et al. 2019

Int. J. Clin. Obstet. Gynaecol.

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Introduction: H1N1 influenza infection is known to cause severe morbidity and mortality in pregnant women. Perinatal morbidity and mortality is also increased due to neonatal disease, prematurity and stillbirth. World Health Organization has identified pregnant and postpartum women as a high risk group. Method: A retrospective observational study was carried out to study the clinical profile and maternalperinatal outcome in pregnant women critically -ill with H1N1 infection at a tertiary care rural medical college of Gujarat. Results: 13 patients fulfilled the admission criteria. There were 4 maternal deaths in the study group. Delay in reporting to the hospital, associated co-morbidities like anemia, bronchial asthma, gestational hypertension was the common factor in pregnant women succumbing to influenza. None of the pregnant women admitted to Intensive care had received Influenza vaccination. Conclusion: Delay in diagnosis and management is associated with poor maternal and perinatal outcome. Influenza vaccination awareness among high risk groups can help in reducing morbidity and mortality due to H1N1 infection.

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Epidemiological characteristics of H1N1 positive deaths: A study from tertiary care hospital in western India

Cited by 5 publications

References 7 publications

Epidemiological & clinical profile of influenza A (H1N1) 2009 virus infections during 2015 epidemic in Rajasthan

Epidemiological & clinical profile of influenza A (H1N1) 2009 virus infections during 2015 epidemic in Rajasthan

An Experience of Pandemic Influenza A (H1N1) 2009 Virus Outbreak in 2017 at Tertiary Care Hospital, Chennai, Tamilnadu, India

A retrospective study of critically-ill pregnant women with H1N1 infection in a tertiary care rural medical college of Gujarat

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