Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study

Caini, Saverio; Huang, Q Sue; Cıblak, Meral A.; Kusznierz, Gabriela; Owen, Rhonda; Wangchuk, Sonam; Henriques, Cláudio Maierovitch Pessanha; Njouom, Richard; Fasce, Rodrigo; Yu, Hongjie; Feng, Luzhao; Zambon, Maria; Clara, Alexey; Kosasih, Herman; Puzelli, Simona; Kadjo, Hervé A.; Emukule, Gideon O.; Héraud, Jean‐Michel; Ang, Li Wei; Venter, Marietjie; Mironenko, Alla; Brammer, Lynnette; Quynh, Lê; Schellevis, François G.; Plotkin, Stanley А.; Paget, John; Rudi, Juan Manuel; Dorji, Kunzang; Marins, José; Almeida, Walquíria Aparecida Ferreira de; Vernet, Marie‐Astrid; Vernet, Guy; Andrade, Winston; Yang, Juan; Li, Ming; Lara, Jenny; Lozano, Celina de; Pebody, Richard; Ellis, Joanna; Green, Helen; Castillo, Leticia; Matute, María Luisa; Nurhayati, .; Donatelli, Isabella; Coulibaly, Daouda; Mott, Joshua A.; Razanajatovo, Norosoa Harline; Randrianasolo, Laurence; Lopez, Liza; Balmaseda, Ángel; Moreno, Brechla; Cutter, Jeffrey; Lee, Vernon J.; Cohen, Cheryl; Badur, Selim; Radchenko, Larysa; Bresee, Joseph S.

doi:10.1111/irv.12319

Cited by 162 publications

(182 citation statements)

References 20 publications

Supporting

Mentioning

142

Contrasting

Unclassified

Order By: Relevance

“…Consistent with other studies,14, 47, 48 influenza B affected children and teenagers more than adults in the study. We found that 2012 had a higher rate of influenza A notifications, with increased notifications particularly in younger children and older adults.…”

Section: Discussionsupporting

confidence: 93%

“…Influenza B accounted for 17% of total notifications in the study. This is slightly lower than the global proportion, with an average of 20% estimated over a similar period from 26 countries across different geographic regions including Australia 14. In that study, the highest median proportion of influenza B was found in tropical regions and the lowest was in the Southern Hemisphere, but when compared between the geographic regions, the differences were not statistically significant.…”

Section: Discussionmentioning

confidence: 57%

“…This result is lower than reported in the United States (46%, from 2001/2002 to 2010/2011 seasons) and the Europe (58%, between 2003/2004 and 2010/2011 seasons) 18. Again, this varies by regions and influenza season globally 14, 18…”

Section: Discussionmentioning

confidence: 66%

“…Influenza B virus circulates in the population alongside influenza A, to varying degrees from season to season and by geographic region 13, 14. Influenza B was first isolated in the 1940s.…”

Section: Introductionmentioning

confidence: 99%

“…The incidence of influenza B infection varies considerably by influenza season and by global region 14. Here, the aim of our study was to describe the epidemiology and contribution of influenza B relative to influenza A in Australia.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Epidemiology of influenza B in Australia: 2001‐2014 influenza seasons

Moa

Muscatello

Turner

et al. 2016

Influenza Resp Viruses

View full text Add to dashboard Cite

BackgroundInfluenza B is characterised by two antigenic lineages: B/Victoria and B/Yamagata. These lineages circulate together with influenza A during influenza seasons, with varying incidence from year to year and by geographic region.ObjectiveTo determine the epidemiology of influenza B relative to influenza A in Australia.MethodsLaboratory‐confirmed influenza notifications between 2001 and 2014 in Australia were obtained from the Australian National Notifiable Diseases Surveillance System.ResultsA total of 278 485 laboratory‐confirmed influenza cases were notified during the study period, comprising influenza A (82.2%), B (17.1%) and ‘other and untyped’ (0.7%). The proportion of notifications that were influenza B was highest in five‐ to nine‐year‐olds (27.5%) and lowest in persons aged 85 years and over (11.5%). Of all B notifications with lineage determined, 77.1% were B/Victoria and 22.9% were B/Yamagata infections. Mismatches between the dominant B lineage in a season and the trivalent vaccine B lineage occurred in over one‐third of seasons during the study years. In general, influenza B notifications peaked later than influenza A notifications.ConclusionThe proportion of circulating influenza B in Australia during 2001‐2014 was slightly lower than the global average and was dominated by B/Victoria. Compared with influenza A, influenza B infection was more common among older children and young adults and less common in the very elderly. Influenza B lineage mismatch with the trivalent vaccine occurred about one‐third of the time.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Epidemiology of influenza B in Australia: 2001‐2014 influenza seasons

Moa

Muscatello

Turner

et al. 2016

Influenza Resp Viruses

View full text Add to dashboard Cite

show abstract

Nucleic acid‐based electrochemical biosensor for detection of influenza B by gold nanoparticles

Yahyavi,

Edalat,

Pirbonyeh

et al. 2023

J of Molecular Recognition

View full text Add to dashboard Cite

The influenza virus is a pervasive pathogen that exhibits increased prevalence during colder seasons, resulting in a significant annual occurrence of infections. Notably, pharmaceutical interventions effective against influenza A strains often exhibit limited efficacy against influenza B variants. Against this backdrop, the need for innovative approaches to accurately and swiftly differentiate and detect influenza B becomes evident. Biosensors play a pivotal role in this detection process, offering rapid, specific, and sensitive identification of the virus, facilitating timely intervention and containment efforts. Oligonucleotide sequences targeting the conserved B/Victoria/2/87 influenza virus NP region were designed. Nasopharyngeal swabs were collected from patients suspected of influenza virus infection, and viral RNA was extracted. RNA quality was assessed through one‐step PCR. cDNA synthesis was performed using random hexamers, and real‐time PCR quantified the influenza genome. Gold nanoparticles were immobilized on a surface to immobilize the specific DNA probe, and electrochemical hybridization was electrochemically followed. The biosensor exhibited high selectivity and effective distinction of complementary sequences from mismatches and influenza virus cDNA genome. The biosensor successfully detected the influenza B virus genome in real samples. Non‐influenza samples yielded no significant hybridization signals. The comparison between the results obtained from the biosensor and real‐time PCR revealed full agreement of these methods. The biosensor utilized electrochemical detection of hybridization and proved effective in detecting the influenza B virus genome with high specificity, sensitivity, and selectivity. Comparative analysis with real‐time PCR underscored the accuracy and potential applicability of the biosensor in rapid and specific virus detection. This innovative approach holds promise for future diagnostic and epidemiological applications in detecting influenza B virus and other pathogens.

show abstract