Epidemiologic profile of oral squamous cell carcinoma in Yogyakarta, Indonesia

Abstract

Introduction: Oral cancer is a major health problem in the world, indicated by a high incidence of recurrence. In Southeast Asia, oral cancer ranks sixth from all cancers on the human body. The incidence of oral cancer, especially squamous cell carcinoma types, increases every year, but the prognosis and patients life expectancy are still unsatisfying enough and the reports about the profile of oral cancer is still limited.The objective of this research was to get the epidemiological profile of oral squamous cell carcinoma (OSCC) in Yogyakarta, Indonesia. Methods: The research method was observational analytic with cross-sectional design. All new OSCC cases in three anatomic pathology laboratory installations in Yogyakarta (January 2011-December 2015) were included in this study. Data collected were gender, age, anatomical location, and histology. All data were analyzed using statistical analysis program. Results: OSCC new cases amount increasing each year: 6 cases (6.6%) in 2011, and increased to 24 cases (26.4%) in 2015. Fifty-two of the 91 cases (57.1%) were found on male. The age group with the most cases was found in group of 41-60 years (49.5%). There is no difference in the case distribution by age between male and female. Forty-eight cases were found in the lingual part (52.7%). Histological examination showed 68 cases (74.7%) were well-differentiated carcinoma. Conclusion: OSCC profile in Yogyakarta mostly found in men with anatomical location in the lingual part in the age group above 40 years of age and were having well-differentiated histology.

Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009

“…Epidemiological study of a disease provides key information that can be used for understanding the etiology of the disease and to plan preventive and management strategies (Gracia et al, ). This study provides descriptive epidemiology of OSCC and its characteristics in a referral cancer hospital in Nepal from 1999 to 2009.…”

Clinicopathological characteristics predicting advanced stage and surgical margin invasion of oral squamous cell carcinoma: A single‑center study on 10 years of cancer registry data

“…The increasing prevalence of OSCC among Asian countries (13)(14)(15)(16) has demonstrated the value of profiling Indonesian OSCC epidemiology to give a new perspective on this disease and contribute to better prognosis and therapy planning. Previous studies in Indonesia (17)(18)(19)(20) did not report a long study period and did not highlight the role of examining histopathological features. These studies did not assess contributing factors related to advanced-stage cancer and invasion of surgical margins in resected cases.…”

Salivary nitrosamine output voltage levels as an early detection of malignancy in the oral cavity

“…1 Oral cancer or oral squamous cell carcinoma (OSCC) is the sixth malignant disease in the world. [2][3][4] found on the lips and buccal mucosa, gingiva, hard palate, tongue and floor of the mouth. 4 From 2007-2016, the United States reported an increased incidence of oral and pharyngeal cancer.…”

“…5 Gracia reported that in 2011-2015 found, 49 cases of OSCC were in the lingual area (53.8%), buccal area (20.9%), and palatal area (12.1%). 3 Oral cancer spreads rapidly and usually are diagnosed at an advanced stage with a high mortality rate. Only half of the diagnosed cases will survive more than five years, but if the cancer is detected early, about 80-90% will survive.…”