Epidemiologic Panorama of Stomach Cancer Mortality in Mexico

Tovar-Guzmán, Víctor José; Hernández–Girón, Carlos; Barquera, Sı́món; Rodrı́guez-Salgado, Norma; López‐Carrillo, Lizbeth

doi:10.1016/s0188-4409(01)00290-9

Cited by 27 publications

(15 citation statements)

References 10 publications

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“…Previous publications describing the burden of cancer in Mexico have been limited in scope because of the analysis of only short time periods, inclusion of a limited number of cancers, [20][21][22][23][24][25][26][27] incomplete or too broad geographical coverage, [28][29][30][31] or special settings like the population covered by the social security system. [32][33][34] It has therefore been difficult to assess cancer trends across the country.…”

Section: Discussionmentioning

confidence: 99%

The burden of cancer in Mexico, 1990-2013

et al. 2016

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Objective. To analyze mortality and incidence for 28 cancers by deprivation status, age and sex from 1990 to 2013. Materials and methods. The data and methodological approaches provided by the Global Burden of Disease (GBD 2013) were used. Results. Trends from 1990 to 2013 show important changes in cancer epidemiology in Mexico. While some cancers show a decreasing trend in incidence and mortality (lung, cervical) others emerge as relevant health priorities (prostate, breast, stomach, colorectal and liver cancer). Age standardized incidence and mortality rates for all cancers are higher in the northern states while the central states show a decreasing trend in the mortality rate. The analysis show that infection related cancers like cervical or liver cancer play a bigger role in more deprived states and that cancers with risk factors related to lifestyle like colorectal cancer are more common in less marginalized states. Conclusions. The burden of cancer in Mexico shows complex regional patterns by age, sex, types of cancer and deprivation status. Creation of a national cancer registry is crucial.Keywords: cancer; burden of disease; mortality; incidence; social condition; cause of death; epidemiology ResumenObjetivo. Analizar la incidencia y la mortalidad de 28 tipos de cáncer por nivel de marginación, grupos de edad y sexo, de 1990 a 2013. Material y métodos. Los datos utilizados provienen del estudio de la Carga Global de Enfermedades (2013). Las entidades federativas se clasificaron de acuerdo con el índice de marginación del Consejo Nacional de Población. Resultados. Los datos muestran una tendencia decreciente para algunos cánceres (pulmón y cervical), mientras otros aparecen como prioritarios y relevantes (próstata, mama, estómago, colon e hígado). En el norte se observan incrementos regionales mayores en las tasas de incidencia y mortalidad estandarizadas por edad, mientras que en los estados del centro se observa una tendencia decreciente de la tasa de mortalidad. Conclusiones. La epidemiología del cáncer en México (en su mayoría basada en datos de mortalidad) presentan patrones regionales complejos por edad, sexo, tipo de cáncer e índice de marginación. Es vital la creación de un registro nacional para mejorar el seguimiento y evaluación de intervenciones preventivas y curativas.

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Section: Discussionmentioning

confidence: 99%

The burden of cancer in Mexico, 1990-2013

et al. 2016

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“…Other analyses on mortality from selected cancers in Mexico for the period 1980 -1995 reported increasing trends for cancers of the lung [7], breast [8], colorectum [9], prostate [10] and stomach [11]. Inconsistent trends were reported for cervical cancer [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Trends in cancer mortality in Mexico, 1981–2007

Bosetti

Rodrı́guez

Chatenoud

et al. 2011

European Journal of Cancer Prevention

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“…Gastric cancer is the fourth most common cancer and the second leading cause of cancer-associated deaths in the world. Although the incidence of gastric cancer has been steadily decreasing, in some developing nations, such as Chile, it has remained stable during the last 20 years (6); or even slightly increased, like in Mexico (7).…”

Section: Introductionmentioning

confidence: 99%

Age and Severity of Mucosal Lesions Influence the Performance of Serologic Markers in Helicobacter pylori–Associated Gastroduodenal Pathologies

Camorlinga‐Ponce

Flores-Luna

Lazcano‐Ponce

et al. 2008

Cancer Epidemiology, Biomarkers &Amp; Prevention

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Objective: The course of Helicobacter pylori infection and antibody response to CagA in patients with preneoplastic lesions and gastric cancer has not been thoroughly studied. We aimed to study H. pylori infection and antibody response to CagA in patients with non -atrophic gastritis, preneoplastic lesions, and gastric cancer. Methods: We studied patients attending one Oncology Hospital and one General Hospital in Mexico City. Diagnosis was based on endoscopy and histopathology in biopsies from six stomach regions. H. pylori infection was assessed by histology and serology, and antibodies against CagA were measured with immunoassay. Results: We included 618 patients, 368 with nonatrophic gastritis, 126 with precancerous lesions, and 65 with gastric cancer; in addition, 59 patients with duodenal ulcer were studied. Detection of infection and IgG against CagA had a significant increase from nonatrophic gastritis to mild and up to advanced stages of metaplasia (P < 0.05), followed by decreased infection and IgG to CagA in patients with gastric cancer (P < 0.05). However, infection and CagA antibodies were associated with young gastric cancer cases. Duodenal ulcer showed a significant association with infection detected by histology and serology, particularly among women, and a trend to associate with IgG to CagA. Conclusions: This study shows that H. pylori infection and CagA are risk markers for intestinal metaplasia. The prevalence of these risk markers decreases in gastric cancer, probably reflecting that infection decreases after advanced atrophy and metaplasia in the gastric mucosa. State of the disease, age, and sex influence the association of H. pylori infection and IgG response to CagA with gastroduodenal diseases. (Cancer Epidemiol Biomarkers Prev 2008;17(9):2498-504)

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Epidemiologic Panorama of Stomach Cancer Mortality in Mexico

Cited by 27 publications

References 10 publications

The burden of cancer in Mexico, 1990-2013

The burden of cancer in Mexico, 1990-2013

Trends in cancer mortality in Mexico, 1981–2007

Age and Severity of Mucosal Lesions Influence the Performance of Serologic Markers in Helicobacter pylori–Associated Gastroduodenal Pathologies

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