Epidemiologic Characteristics and Management of Subjects Who Were Diagnosed with Trophoblastic Disease

Yumru, Ayşe Ender; Çakmak, Burcu Dinçgez; Ondes, Banu; Bozyiğit, Abdülhamit

doi:10.5152/etd.2012.33

Cited by 1 publication

(2 citation statements)

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“…younger than 20 and older than 35 years (15,16). GTD in Turkey usually occurs at ages from 19-35 years (11,17). We found that blood type A (45.9%) was the most frequent, and this is the most common maternal blood type A in the literature (8,11).…”

Section: Discussionmentioning

confidence: 99%

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Incidence of gestational trophoblastic disease in Tokat province, Turkey

Çakmak¹,

Toprak²,

Nacar³

et al. 2014

J Turkish German Gynecol Assoc

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59,754 births in Tokat province. During this period, 73 cases were diagnosed as GTD histopathologically. The calculated GTD incidence was 1.22 per 1000 births. The mean age of the diagnosed patients was 28.6±7.3 (range 17-51) years. Many patients were aged 20-29 years (Figure 1). The mean numbers of pregnancies, births, and abortions were 3.5±2.9 (range 1-15), 1.3±1.4 (range 0-5), and 1.1±2.3 (range 0-13),Objective: This study investigated the incidence of gestational trophoblastic disease (GTD) in Tokat province, Turkey. Material and Methods:The medical records of patients who had been diagnosed and treated at one university hospital, six government hospitals, and one specialist hospital in Tokat province between January 2005 and December 2012 were evaluated retrospectively.Results: During the study period, there were 59,754 births and GTD was diagnosed in 73 cases. The calculated GTD incidence was 1.22/1000. The mean age of the patients diagnosed with GTD was 28.6±7.3 (range 17-51) years. In GTD, complete moles occurred in 26%, partial moles in 74%, and no invasive moles, choriocarcinomas, or placental site trophoblastic tumours were found. Only two patients received chemotherapy (methotrexate). There was no mortality associated with the disease during follow-up. Conclusion:The incidence of GTD in Tokat province was 1.2 per 1000 births. Early diagnosis, treatment, and follow-up play a critical role in preventing the morbidity and mortality associated with disease. The incidence of GTD, which has a high recovery rate with adequate treatment and follow-up, can be determined from regional and community-based research. (J Turk Ger Gynecol Assoc 2014; 15: 22-4) Key words: Gestational trophoblastic disease, molar pregnancy, incidence Received: 11 October, 2013 Accepted: 09 November, 2013 Incidence of gestational trophoblastic disease in Tokat province, Turkey

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Section: Discussionmentioning

confidence: 99%

“…GTD in Turkey usually occurs at ages from 19-35 years (11,17). We found that blood type A (45.9%) was the most frequent, and this is the most common maternal blood type A in the literature (8,11). Vacuum curettage, hysterectomy, and chemotherapy are usually used to treat GTD.…”

Section: Discussionmentioning

confidence: 99%