Epidemiologic Benefits of Pneumococcal Vaccine Introduction into Preventive Vaccination Programs

Malchrzak, Wojciech; Mastalerz-Migas, Agnieszka

doi:10.1007/5584_2020_589

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…Since IPD is most threatening to the youngest children, vaccination should be started as early as possible. Failure to administer all required primary doses decreases and/or shortens immunity against IPD, as does skipping a booster dose [33,34]. Completion of the vaccination schedule is affected by a great many factors including the number of doses required.…”

Section: Discussionmentioning

confidence: 99%

Vaccination against Streptococcus pneumoniae in Children Born between 2015 and 2018 in Poland—How Has the Introduction of Free Compulsory Pneumococcal Vaccination Affected Its Uptake?

Malchrzak,

Babicki,

Mastalerz-Migas

2023

Vaccines

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Starting from 2017, pneumococcal vaccination was added to the Polish vaccination calendar as mandatory for all children born after 2016. The 10-valent conjugate vaccine was selected as mandatory and therefore free of charge. This paper aims to examine the impact of introducing mandatory vaccination on vaccine uptake. For this purpose, an analysis was conducted for 1595 vaccination record sheets from outpatient clinics in Wrocław and surrounding villages for children born 2015–2018. After the introduction of compulsory vaccination, the percentage of children fully vaccinated against pneumococcus increased (60.4% vs. 84.8%, p < 0.001). A significant decrease in the number of children who did not receive any dose of the vaccine was observed (27.8% to 3.3%, p < 0.001). The introduction of compulsory vaccination did not affect the completion of the pneumococcal schedule (11.8% vs. 11.9%). Compulsory PCV10 vaccination resulted in the less frequent choice of the 13-valent vaccine (72.3% vs. 19.9%, p < 0.001). More children in rural outpatient clinics were vaccinated against pneumococcus compared to urban outpatient clinics (84.8% vs. 70.8%, p < 0.001). The introduction of free pneumococcal vaccination increased the proportion of children vaccinated, although it did not affect the rate of discontinuation of the initiated schedule. In Poland, the increased popularity of the 10-valent vaccine at the expense of the 13-valent one translated into a change in the proportion of pneumococcal serotypes causing invasive pneumococcal disease.

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Section: Discussionmentioning

confidence: 99%

Vaccination against Streptococcus pneumoniae in Children Born between 2015 and 2018 in Poland—How Has the Introduction of Free Compulsory Pneumococcal Vaccination Affected Its Uptake?

Malchrzak,

Babicki,

Mastalerz-Migas

2023

Vaccines

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Cemeteries and graveyards as potential reservoirs of antibiotic resistance genes and bacteria: a review

Tarnawska,

Walczak,

Burkowska-But

2023

Environ Chem Lett

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The discovery of antibiotics remains one of the greatest achievements of the last century. Unfortunately, due to their overuse and misuse, the occurrence of resistance to antibiotics has become one of the most pressing dilemmas for human public health. Many sources of antibiotic resistance are known, including agriculture, animal husbandry, hospitals, sewage treatment plants, and potentially, cemetery soil. There is lack of sufficient evidence on the contribution of the cemetery soil in the introduction of antibiotic resistance into the environment; therefore, this issue needs to be explored. Here, we review the most important pathways for the transfer of antibiotic-resistant microorganisms and their genes and the main factors influencing the spreading efficiency. Unlike other studies on this subject, the article focuses on an area that seems to be overlooked, the cemetery soil environment. The presented data highlight the importance of cemetery soil in the spread of antibiotic-resistant microorganisms and their genes into the environment, which may help identify appropriate solutions to combat this problem more effectively. In addition, the review describes their potential importance in the escalation of the antibiotic resistance phenomenon, along with different methods of combating antimicrobial resistance.

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Epidemiologic Benefits of Pneumococcal Vaccine Introduction into Preventive Vaccination Programs

Cited by 2 publications

References 36 publications

Vaccination against Streptococcus pneumoniae in Children Born between 2015 and 2018 in Poland—How Has the Introduction of Free Compulsory Pneumococcal Vaccination Affected Its Uptake?

Vaccination against Streptococcus pneumoniae in Children Born between 2015 and 2018 in Poland—How Has the Introduction of Free Compulsory Pneumococcal Vaccination Affected Its Uptake?

Cemeteries and graveyards as potential reservoirs of antibiotic resistance genes and bacteria: a review

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