Epidemiologic Aspects of Atrial Fibrillation in a Tertiary Hospital in a Sub-Saharan Africa Setting

Douala,; Specialties,; Yaoundé,; Cameroon,

doi:10.4236/oalib.1103384

Cited by 3 publications

(6 citation statements)

References 10 publications

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“…It is well known that the risk of AF increases with age and is higher in patients with cardiovascular diseases and cardiovascular risk factors such as hypertension, diabetes mellitus, obesity, smoking, and alcohol abuse [24]. The majority of our AF patients had severe structural heart disease (93.1%) with hypertensive heart disease being the most prevalent and that is consistent with findings from SSA [5, 6, 22]. Hypertension was the most common risk factor of AF (59.41%) as stated by previous reports [4, 22, 25–27].…”

Section: Discussionsupporting

confidence: 89%

“…This present prospective cohort study was the first one to provide a hospital-based prevalence of AF (5.9%) in rural Burkina Faso. Previous studies in SSA have reported comparable findings however in urban populations [5, 6, 19]. In a rural Ghana, AF was reported to be scarce in a traditional African community accounting for 0.3% of 924 individuals aged of 50 years and above [20].…”

Section: Discussionmentioning

confidence: 64%

“…The mean age of our patients was 66.56 ± 14.92 years and is similar to that of Ntep-Gweth et al [22] in Cameroon with 65.8 ± 13 years. Conversely, most studies in SSA reported more younger age below 60 years [4–6, 23]. It is well known that the risk of AF increases with age and is higher in patients with cardiovascular diseases and cardiovascular risk factors such as hypertension, diabetes mellitus, obesity, smoking, and alcohol abuse [24].…”

Section: Discussionmentioning

confidence: 99%

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Epidemiology and long-term prognosis of atrial fibrillation in rural African patients

et al. 2019

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BackgroundFew studies have addressed the pattern of atrial fibrillation (AF) in rural Africa. The purpose of the study was to assess the epidemiology and long-term prognosis of AF in rural African patients in the Regional Hospital Center (RHC) of Tenkodogo, Burkina Faso.ResultsOverall, 107 of 1805 cardiac cases presented with AF (prevalence of 5.9%). Six patients were excluded. Mean age was 66.56 ± 14.92 years, and 53.47% were female. Hypertension was the most prevalent cardiovascular risk factor (59.41%). Congestive heart failure (HF) was reported in 85.15% of the study patients at presentation. Most of the study population presented with severe underlying heart disease (93.1%), and hypertensive heart disease was the most prevalent with 45.54% of the cases. The mean CHA2DS2VASc score in patients with non-valvular heart disease (n = 91) was 3.33 ± 1.25 (extremes 1–6) while the risk of bleeding was low (HAS-BLED score ≤ 1) in 82 patients (81.2%). Oral anticoagulation was prescribed in few cases (5.26%). During a follow-up period of 74.43 ± 23.94 weeks, acute HF and stroke occurred in respectively 43 and 6 patients. Forty-one patients (40.59%) died. The overall survival rate was 69% at 6-month and 59.4% at 1-year follow-up. Patients with idiopathic dilated cardiomyopathy were at higher risk of death than other patients (log-rank test = 11.88, p < 0.001) over time.ConclusionAF is not rare in rural African patients and is associated with an increased long-term risk of HF, stroke, and mortality.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

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Epidemiology and long-term prognosis of atrial fibrillation in rural African patients

et al. 2019

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“…8 Outros estudos em países de baixa renda mostraram também resultados similares aos nossos no que concerne a frequência e idade. [22][23][24] A ocorrência de FA necessita de melhor compreensão e esclarecimento em países de baixa e média renda. Alguns factores como o tratamento inadequado, a sub-notificação de casos e a predisposição genética poderão estar na base para a baixa prevalência e incidência relatada na região africana.…”

Section: Resultsunclassified

Fibrilhação auricular em adultos com insuficiência cardíaca num hospital terciário em Angola: Estudo retrospectivo

Gonçalves,

Rocha,

Lopes

et al. 2023

Rev. Ang. de Ciênc. da Saúde

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Introdução: A Fibrilação Auricular (FA) é a arritmia sustentada mais comum na população adulta. O objectivo desta pesquisa é determinar a frequência, etiologia, evolução, tratamento e evolução dos pacientes diagnosticados com FA internados por insuficiência cardíaca (IC) num hospital terciário em Luanda, Angola. Métodos: Trata-se de um estudo descritivo, transversal e retrospectivo, sobre o perfil clínico de pacientes diagnosticados com FA internados por IC num hospital público terciário de Luanda, Angola. A normalidade da distribuição dos dados foi analisada por meio do teste de Kolmogorov-Smirnov. As variáveis qualitativas foram expressas em frequências absolutas e relativas. As variáveis quantitativas foram expressas como média ± desvio padrão (DP) ou mediana. Resultados: Dos 461 pacientes internados com IC, 32 (6,9%) indivíduos foram diagnosticados com FA. A média de idade dos participantes foi de 59,56±15,9 anos e 65,6% da amostra era do sexo feminino. Os principais factores de risco foram hipertensão arterial (68,8%) e hábitos alcoólicos (46,9%). As principais causas de IC foram cardiopatia hipertensiva, 19(59,4%), cardiomiopatia dilatada, 8(25%) e valvulopatia mitral reumática, 5(15,6%). Foi prescrita previamente varfarina em 8(25%) indivíduos e aspirina em 21(65,6%), betabloqueador em 15(46,9%) indivíduos, digoxina em 14(43,8%) e amiodarona em (9,4%). As complicações mais frequentes foram: acidente vascular cerebral em 15(46,8%), ocorreram 6 óbitos (18,75%). Conclusão: O nosso estudo mostra uma baixa frequência de fibrilhação auricular em doentes com IC em comparação com a encontrada em estudos semelhantes na África Subsaariana.

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This thromboembolic risk is assessed using the CHA 2 DS2-VASc score prior to anticoagulation [29][30][31].

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mentioning

confidence: 99%

Clinical and Therapeutic Aspects of Ischemic Stroke in Atrial Fibrillation at the Neurology Department of CHU Conakry

MA,

CO,

et al. 2024

J Neurol Res Rev Rep

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Introduction: The main cause of ischemic stroke in our setting is atrial fibrillation. The aim of this study was to evaluate the clinical and therapeutic aspects of atrial fibrillation during ischemic stroke. Material and Methods: We conducted a retrospective descriptive study lasting one year from November 1, 2020 to November 31, 2021, involving all patients with ischemic stroke diagnosed by CT or MRI. We included patients with atrial fibrillation confirmed by a 12-lead électrocardiogrammes (ECG) or a 24-hour ECG holter. Thromboembolic risk was assessed by the CHA2DS2Vasc score and bleeding risk by the HAS-BLED score. Results: A total of 1,400 patients (19.64%) were enrolled. Mean age was 57.3 +/-16.64 years, predominantly female (54.5%), with hypertension as a risk factor (45.09%). The mean NIHSS score was 17.9 +/-3.2, associated with disorders of consciousness (44.36%) and hemiplegia (100%). atrial fibrillation was persistent in 54.90% of cases. A CHA2DS2-VASc score ≥ 2 was found in 94.9% of cases, and a low HAS-BLED score in 73% of cases, for whom Rivaroxaban was the first-line treatment in 76.72% of cases. Conclusion: This study has shown that atrial fibrillation is common in cardioembolic cerebral infarctions with age and hypertension as risk factors.

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Epidemiologic Aspects of Atrial Fibrillation in a Tertiary Hospital in a Sub-Saharan Africa Setting

Cited by 3 publications

References 10 publications

Epidemiology and long-term prognosis of atrial fibrillation in rural African patients

Epidemiology and long-term prognosis of atrial fibrillation in rural African patients

Fibrilhação auricular em adultos com insuficiência cardíaca num hospital terciário em Angola: Estudo retrospectivo

Clinical and Therapeutic Aspects of Ischemic Stroke in Atrial Fibrillation at the Neurology Department of CHU Conakry

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