Epidemiologic Analysis of Gastric Carcinoma in the Western Region of Nepal

Ghosh, Arnab; Sathian, Brijesh; Ghartimagar, Dilasma; Narasimhan, Raghavan; Talwar, OP

doi:10.3126/nje.v1i1.4109

Cited by 7 publications

(13 citation statements)

References 30 publications

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“…Demographically, Gastric cancer was found commonly in 61-70 years, and in Gurung community (Janajati-Hill in our category) in a study by Ghosh et al 13,23 In our series, though Janajatis comprise 37% of the population, they accounted for 42% of cases of gastric carcinomas and around 65% of the patients were concentrated on 20 districts (25% of the geography). Since these patients belong to the hilly region of the country, it limits their accessibility to health care facilities and devoid them of the benefit of early diagnosis and cure.…”

Section: Discussionsupporting

confidence: 45%

“…However, it demonstrates a pattern observed in similar studies done in the past. 23 Gastric cancer involves a combination of genetic, sociocultural and environmental factors. In countries like Nepal with limited resources, diverse ethnicity and difficult terrains, it is of paramount importance to determine the epidemiology of the disease for the judicial utilization of resources.…”

Section: Discussionmentioning

confidence: 99%

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Post Operative Diagnosis of Early Gastric Cancer in a Low Risk Population and the Possibility of Risk Stratified Screening

Ghimire

Singh²,

Timalsina

2015

Kathmandu Univ. Med. J.

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Background Gastric cancer is the second commonest cause of cancer related mortality worldwide. Though its incidence is more in Eastern Asia, it is increasing in the South Asian subcontinent. The diagnosis of early gastric cancer (EGC) confined to the mucosa or submucosa, is an important concern due to a better outcome at this stage where five year survival rates could increase by 90 percent. Though mass screening is done in few countries, it has not been applied in developing countries like Nepal. Preoperative diagnosis of EGC is rare in Nepal. The aim of this study is to analyze the clinico-pathological features of postoperative cases of gastric cancer managed in a tertiary care university hospital of Nepal.Methods All patients with histological diagnosis of gastric cancer admitted in the Department of Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal during the three year period (September 2010 to August 2013) were analyzed retrospectively.Results Ninety two patients with endoscopic diagnosis of gastric cancers were admitted during the past three years. The mean age was 60 years ranging from 28 years to 85 years with the male to female ratio of 2.8:1. Five patients were younger than 40 years and all were in advanced stage. Thirty five percent of the patients belonged to Janajatis (Hill) community though they comprise only 23% of the population and about 65% of them belonged to an area involving 25% of the country.Seventy six cases were operated. Out of 92 patients, 4 patients were diagnosed as early gastric cancer postoperatively. All patients with early gastric cancer were above 50 years with CT Scan abdomen revealing focal thickening without lymphadenopathy.Conclusion Over the years, the incidence of gastric cancer is increasing in Nepal. Though 92% are advance gastric cancers, few have been diagnosed and treated early. A screening program in a country like Nepal with diverse ethnicity and difficult terrain might be helpful if it targets high risk people in high risk areas.Kathmandu University Medical Journal Vol.12(1) 2014: 32-37

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Section: Discussionsupporting

confidence: 45%

Section: Discussionmentioning

confidence: 99%

Post Operative Diagnosis of Early Gastric Cancer in a Low Risk Population and the Possibility of Risk Stratified Screening

Ghimire

Singh²,

Timalsina

2015

Kathmandu Univ. Med. J.

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“…In this study we came to know that Tibeto-mangoloids ethnic group show more risk to gastric cancer due to their food consumption habits where as Indo-Aryans and Dalit /others show less prevalence. An epidemiological study done by Ghosh et al 20 shows 32% of Gurungs (Tibeto-mongoloids) were affected by gastric cancer than their other counterparts which supports our study which is 35.2%.…”

Section: Discussionsupporting

confidence: 90%

“…In our study, majority of the patients with gastric cancer were in the age range of 40 to 60 years which corroborates well with the study done by Gosh et al which shows the increase in incidence after 50 years. 20 The study has demonstrated that the higher consumption of different types of salty packet food, fermented food like preserved pickles and gundruk (our local savory in Nepal) and salted smoked meat are found to incur high risk for gastric cancer. Gundruk is preserved spinach which is traditionally prepared by keeping it tightly packed moist vegetable in a jar for a few weeks or months, allowing fermentation.…”

Section: Discussionmentioning

confidence: 99%

A Study of Salty Processed Food Consumption Pattern among Different Ethnic Group in Patient with Gastric Cancer

Pun¹,

Katwal²,

Mahaseth³

2020

Nep. Med. Coll. J.

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Gastric cancer is the fourth most frequently occurring malignancy, after lung, breast and colorectal cancer, and the second most common cause of death from cancer worldwide. The global incidence of gastric cancer shows wide geographic variation with a 15-20 fold difference between high and low incidence region. Therefore the prevention of gastric cancer represents one of the most important aspects of any cancer control strategy around the world. From the hospital based data in Nepal gastric cancer is the third most common cancer in males and the sixth common cancer in females. An observational hospital based descriptive study was carried out in the Oncology Unit of (NMCTH) from 2013-2018 on relationship between salty processed food consumption and increased possibility of development of gastric cancer in different ethnic groups of Nepal. Fifty-four diagnosed gastric cancer patients were enrolled and their dietary habits were extensively looked into. Of these 55.6% (30) were males and 44.4% (24) were females. The patient’s age ranged between 25-75 years and the peak incidence was in age group 41-60 years. The habit of consumption of smoked meat was higher (77.8%) than the consumption of packed food and fermented food. Tibeto-mongoloid ethnicity was found to have more prevalence (64.8%) to gastric cancer. The common site of presentation of gastric cancer was at the antrum (44.4%) and tubular adenocarcinoma was the most common type. It was the Tibeto-mongoloids whose food habit pattern comprised of major consumption of salty processed food and having more preference for salty processed food in daily life had increased high risk of gastric cancer than the other ethnic groups. This concludes that food consumption pattern play a critical role in the incidence of gastric cancer and dietary modification to reduce salt and salted food is a practical strategy with which gastric cancer risk can be prevented in these high risk ethnic group of Nepal.

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“…8 Among different studies conducted in Nepal fifty percent of patients belonged to Brahmin and Chhetris (Hill) followed by Janajatis (Hill) 35% and Newars 11%, both of whom belonged to the Janajatis and amongst them it was more frequently observed in the Gurung and Sherpa community. 9,10 The incidence of gastric cancer is known to increase with age with the peak incidence occurring at 60-80 years. 11 In a study done in Nepal more than half of the patients (55.7%) were in age group of 50-70 years with the mean age of 59.6 years and male to female ratio of 2:1.…”

Section: Discussionmentioning

confidence: 99%

Gastric Cancer in Nepal A Locally Advanced Disease

Koirala¹,

Acharya²,

Khanal³

et al. 2019

Nep. Med. Coll. J.

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The goal of this study is to describe the distribution of gastric cancer by age, gender, duration of symptoms, nutritional status and staging of the disease based on operative findings and correlation between the data. This was an observational study. The study was conducted at Department of Surgery, Nepal Medical College Teaching Hospital from December 2012 to December 2017. All patients who were admitted to the department with a diagnosis of stomach cancer and underwent palliative or curative intent procedure were reviewed and analyzed. Out of the 80 patients, 51(63.7%) were male and 29 (36.3%) patients were female. The disease was commonest in the 6th and 7th decades of life. Majority of the patients were of Tibetoburmese (Mongolian) origin with 44 (55%). Majority of patients, 60 (75%) patients had long duration of illness of more than 6 months. Most of the patients had albumin level less than 3gm/dl. Gastric carcinoma is a male predominant malignancy usually of old age and commonly observed in the Tibeto-Burman group of people. Overwhelming majority diagnosed at an advanced stage and had poor prognosis.

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Epidemiologic Analysis of Gastric Carcinoma in the Western Region of Nepal

Cited by 7 publications

References 30 publications

Post Operative Diagnosis of Early Gastric Cancer in a Low Risk Population and the Possibility of Risk Stratified Screening

Post Operative Diagnosis of Early Gastric Cancer in a Low Risk Population and the Possibility of Risk Stratified Screening

A Study of Salty Processed Food Consumption Pattern among Different Ethnic Group in Patient with Gastric Cancer

Gastric Cancer in Nepal A Locally Advanced Disease

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