Epicutaneous Testing

Hannuksela, Matti

doi:10.1111/j.1398-9995.1979.tb01994.x

Cited by 33 publications

(10 citation statements)

References 33 publications

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“…Patch test methods and reading were according to internationally accepted criteria (4, 5). The patch test sites were evaluated initially at 2 or 3 days (D).…”

Section: Methodsmentioning

confidence: 99%

Fragrance contact dermatitis: a worldwide multicenter investigation (Part II)

Larsen

Nakayama²,

Fischer³

et al. 2001

Contact Dermatitis

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The purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 178 patients were evaluated in 8 centers worldwide with a fragrance mix (FM) and 20 other fragrance materials. Reaction to the fragrance mixture (FM) occurred in 78.7% of the subjects. Substances reacting at a rate of 2% or higher included jasmine absolute, geranium oil bourbon, l-citronellol, spearmint oil, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-gamma-2-benzopyran, omega-6-hexadecenlactone, dimethyltetrahydrobenzaldehyde (isomer mixture), and alpha-amylcinnamaldehyde. These chemicals should be furthur evaluated to corroborate their allergenicity. We are constantly looking for new fragrance allergens to extend the diagnostic capability of the fragrance mix (FM).

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“…Patch test methods and reading were according to internationally accepted criteria (4, 5). The patch test sites were evaluated initially at 2 or 3 days (D).…”

Section: Methodsmentioning

confidence: 99%

Fragrance contact dermatitis: a worldwide multicenter investigation (Part II)

Larsen

Nakayama²,

Fischer³

et al. 2001

Contact Dermatitis

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“…Between January 1990 and April 1991, 1158 patients were seen and patch tested in our Allergy Unit; the scoring method recommended by the ICDRG was used for scoring the results (2). An patients were patch tested with the GIRDCA (Gruppo Italiano Ricerca Dermatiti da Contatto Ambientali) standard series; the patch test chemicals were supplied by Hermal (Reinbek, Germany) and by FIR-MA S.p.A. (Florence, Italy).…”

Section: Methodsmentioning

confidence: 99%

Eyelid dermatitis: an evaluation of 150 patients

et al. 1992

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This study was performed to evaluate eyelid dermatitis in a group of patients of our Allergy Unit between January 1990 and April 1991. Among the 1158 patients seen during this period, 150 had eyelid dermatitis: 135 females and 15 males, with a mean age of 35 years. Of the 150 patients with eyelid dermatitis, 54 had eczema localized to the eyelids only, 49 to the eyelids and face, 19 to the eyelids and hands, and 28 to the eyelids and other sites. 98 patients (65.3%) were diagnosed as having allergic contact dermatitis, 25 (16.6%) irritant contact dermatitis, 21 (14%) atopic dermatitis, and 6 (4%) seborrhoeic dermatitis. Patch test reactions to nickel sulphate, Kathon CG and fragrance-mix occurred more frequently in patients with eyelid dermatitis than in those without.

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“…Results were read at D2, D4 or D3 alone. The reading at D3 or D4 was considered positive, if the reaction was equal to or stronger than a palpable erythema, according to the guidelines of the International Contact Dermatitis Research Group (12). Most patients were followed‐up 3 times in the following 2 months to confirm the diagnosis and relevance of positive reactions.…”

Section: Methodsmentioning

confidence: 99%

A patch test study of 27 crude drugs commonly used in Chinese topical medicaments

et al. 2003

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Chinese topical medicaments (CTMs) are commonly used in Taiwan and in Southeast Asia. However, a systematic evaluation of contact sensitization potential from CTM has not been carried out to our knowledge. This study was undertaken to investigate the incidence of contact sensitivity to the components of CTM in patients with contact dermatitis from CTM. A screening series of 27 crude drugs most commonly used in CTM as well as a modified European standard series was patch tested in 30 patients. The herbs with the most frequent positive reactions were Flos Caryophylli (see text), Radix Angelicae Pubescentis (see text), Cortex Cinnamomi (see text), Cortex Radix Acanthopanacis (see text), Caulis Impatientis (see text), Resina Draconis/Sanguis Draconis (see text), Fructus Cnidii (see text), Radix Gentiana Macrophyllae (see text), and Rhizoma Ligustici Chuanxiong (see text). Concomitant allergy to colophonium was found in most of these positive reactions. Reducing the concentration and simplifying the compositions of these components, as well as replacement with those of low allergenicity in CTM, such as Rhizoma Arisaematis (see text), Herba Lycopodii (see text), Radix Cyathulae Officinalis (see text), Rhizoma Pinelliae (see text), Radix Angelicae Dahuricae (see text), Herba Dendrobii (see text), Secretio Moschus (see text), and Stigmata Croci (see text), may be advocated. A precise labelling of the dosage of each component and the exact chemical compounds in CTM products could further improve the safety and therapeutic effects of CTM in the future.

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Epicutaneous Testing

Cited by 33 publications

References 33 publications

Fragrance contact dermatitis: a worldwide multicenter investigation (Part II)

Fragrance contact dermatitis: a worldwide multicenter investigation (Part II)

Eyelid dermatitis: an evaluation of 150 patients

A patch test study of 27 crude drugs commonly used in Chinese topical medicaments

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