Epicardial adipose tissue thickness is a predictor for plaque vulnerability in patients with significant coronary artery disease

Park, Jin-Sun; Choi, So‐Yeon; Zheng, Mingri; Yang, Hyoung‐Mo; Lim, Hong–Seok; Choi, Byoung-Joo; Yoon, Myeong‐Ho; Hwang, Gyo‐Seung; Tahk, Seung‐Jea; Shin, Joon-Han

doi:10.1016/j.atherosclerosis.2012.11.001

Cited by 36 publications

(26 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…53 Several studies have stated that there is a relationship between an increased EAT and plaque vulnerability. [54][55][56] Noninvasive imaging biomarkers, identified by computed tomography coronary angiography, include the coronary artery calcium score, low-density plaques with an increased necrotic core, the presence of spotty calcifications and the napkinring sign. 57,58 Biomarkers for plaque instability, detected by advanced imaging methods such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT)…”

Section: 50-52mentioning

confidence: 99%

Original research. The Assessment of Epicardial Adipose Tissue in Acute Coronary Syndrome Patients. A Systematic Review

Benedek

Raț

Hodaş³

et al. 2017

Journal of Cardiovascular Emergencies

View full text Add to dashboard Cite

show abstract

Section: 50-52mentioning

confidence: 99%

Original research. The Assessment of Epicardial Adipose Tissue in Acute Coronary Syndrome Patients. A Systematic Review

Benedek

Raț

Hodaş³

et al. 2017

Journal of Cardiovascular Emergencies

View full text Add to dashboard Cite

show abstract

“…Furthermore, the myocardial ischemia-related ventricular repolarization parameters Tp-e and Tp-e/QT are also increased in patients with thicker EAT [11]. A study by Park et al that evaluated the association between EAT thickness and plaque structure using virtual histology intravascular ultrasound (VH-IVUS) revealed that thin-cap fibroatheromas (TCFAs) and higher necrotic core burden are associated with EAT thickness [12]. It is also a fact that echocardiography, one of the most common methods for evaluating EAT, has limitations related to echocardiographic acoustic window quality and to which EAT thickness localization represents CAD risk more appropriately.…”

Section: Discussionmentioning

confidence: 99%

The Relationship Between Epicardial Adipose Tissue Volume and Coronary Plaque Structure in Diabetics

Aksan¹

2017

Ann Clin Anal Med

View full text Add to dashboard Cite

Anahtar KelimelerEpikardiyal Yağ Dokusu; Koroner Arter Hastalığı; Koroner Plak Abstract Aim: Epicardial adipose tissue (EAT) contributes to the development and progression of coronary artery disease (CAD). We aimed to evaluate the relationship between EAT volume, coronary atherosclerosis, coronary plaque burden, and plaque structure in diabetic patients. Material and Method: 196 DM patients who were evaluated with 128-slice dual-source coronary computed tomography angiography (CCTA) for suspected CAD were included in the study. The CCTA examination was used to assess the total plaque burden, number of diseased segments, plaque characteristics, and EAT volume. The study population was divided into two groups [a CAD group (Group I) and non-CAD group (Group II)]. The plaque characteristics were analyzed on a per-segment basis. Results: EAT volume was found to be significantly higher among diabetic patients with CAD compared to those without CAD ( 138.7±49.1 ml vs 98.6±34.7 ml, p<0.001). In the correlation analysis, EAT volume showed significant positive correlation with BMI (r=0.369, p<0.001), total plaque burden (r=0.424, p<0.001), mixed plaques (r=0.454, p<0.001), non-calcified plaques (r=0.369, p<0.001), calcified plaques (r=0.191, p=0.007), and number of diseased segments (r=0.449, p<0.001). Also, multivariate logistic-regression analysis revealed that EAT volume to be a significant and independent predictor of the presence of CAD in patients with DM (OR=1.023, 95% CI: 1.014-1.032; p<0.001). Discussion: We have determined that EAT volume is an independent predictor among diabetic patients for the presence of CAD. Moreover, EAT volume showed moderate correlation with total plaque burden and the number of mixed and non-calcified plaques but weak correlation with calcified plaques.

show abstract

“…To the best of our knowledge, this is the first study to describe the association between the EAT and the development of coronary atherosclerosis in nonIRAs in AMI patients. Recently, several investigations regarding the association between EAT and the development of coronary atherosclerosis have been published [6][7][8][9][11][12][13][14][15][16] . For example, measurements of the EAT can be used to predict coronary artery disease (CAD) in both symptomatic and asymptomatic patients 6-9, 11, 13, 16) , and, in stable CAD patients, a large EAT is closely associated with plaque vulnerability 12,14) .…”

Section: Epicardial Adipose Tissue Thickness and Presence Of Multivesmentioning

confidence: 99%

Association between the Epicardial Adipose Tissue Thickness and the Presence of Multivessel Disease in Patients with Acute Myocardial Infarction

Fukamachi

Higuchi

Hiro

et al. 2015

JAT

View full text Add to dashboard Cite

Aim: Epicardial adipose tissue (EAT) is implicated in the development of coronary atherosclerosis.We sought to investigate the association between the EAT thickness and presence of multivessel disease (MV) in patients with acute myocardial infarction (AMI). Methods: We enrolled 45 consecutive patients with AMI who underwent primary percutaneous coronary intervention (PCI). The EAT thickness was measured on echocardiography. A follow-up study was performed using coronary angiography with coronary angioscopy two weeks after primary PCI.

show abstract

Epicardial adipose tissue thickness is a predictor for plaque vulnerability in patients with significant coronary artery disease

Cited by 36 publications

References 32 publications

Original research. The Assessment of Epicardial Adipose Tissue in Acute Coronary Syndrome Patients. A Systematic Review

Original research. The Assessment of Epicardial Adipose Tissue in Acute Coronary Syndrome Patients. A Systematic Review

The Relationship Between Epicardial Adipose Tissue Volume and Coronary Plaque Structure in Diabetics

Association between the Epicardial Adipose Tissue Thickness and the Presence of Multivessel Disease in Patients with Acute Myocardial Infarction

Contact Info

Product

Resources

About