With recent technological advancements, tunnel boring machines (TBM) have developed and exhibited high performance in large diameters and weak ground conditions. Tunnels are crucial structures that significantly influence the timelines of highway and railway projects. Therefore, the construction of tunnels with TBMs becomes a preferred option. In this study, a comparative analysis between TBM and the New Austrian Tunneling Method (NATM) for tunnel construction is performed in the construction of the T1 tunnel with a diameter of 13 m, which is the longest tunnel in the Eşme‐Salihli section of Ankara‐İzmir High‐Speed Railway Project (Türkiye). The selection of TBM type, measures taken in problematic sections, and application issues of TBM are discussed. The impact of correct description of geological and geotechnical conditions on both selection and performance of TBM is presented. An earth pressure balanced type TBM is chosen for the construction of the T1 tunnel. Because of the additional engineering measures taken before excavation in problematic areas, the tunnel was completed with great success within the initially planned timeframe. From this point of view, this study is an important case and may contribute to worldwide tunneling literature.