EP847 CA 125 as a prognostic marker for the stage of patients with ovarian carcinoma

Ganovska, A; Kovachev, S

doi:10.1136/ijgc-2019-esgo.896

Cited by 1 publication

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“…Serum CA-125 has been playing significant part in observing, treating and differentiating the recurrence of ovarian cancer and it is a prognostic marker for the advanced stages of ovarian cancers. 6,7 In majority of the ovarian cancers cases, CA-125 was over expressed and its levels at presentation were well correlated with histology. 8,9 Various studies have reported other malignant conditions such as in mesothelioma, breast cancer, gastric cancer, leiomyoma, non-Hodgkin lymphoma (NHL) and leiomyosarcoma of gastrointestinal origin, correlated with raised CA-125 levels.…”

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confidence: 98%

Association between Histopathologic Type of Ovarian Cancer and Serum CA-125 Level

Perveen,

Haider,

Kerio

et al. 2023

PAFMJ

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Objective: to find an association between the serum CA-125 level and the histopathological type of ovarian tumor. Study Design: Cross-sectional study. Place and Duration of Study: Medical Oncology, Jinnah postgraduate Medical Center, Karachi Pakistan from Jan 2018 to Dec 2019. Methodology: This study included 107 patients presenting with epithelial ovarian cancer. In each case, histological type, pathological stage, degree of differentiation and serum CA-125 was evaluated. The association between preoperative CA-125 and histopathological type of tumor were evaluated. Result: About 107 ovarian cancer patients were included. The mean age in our study was 50.80±10.16 years. Raised CA-125 level was found in most of the patients with serous histology 46(56.1%). Conclusion: Serum level CA-125 elevated in most patients with serous histology. A statistically non-significant association was found between raise CA-125 levels and histological types of ovarian cancer.

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