EP530 Indocyanine green in surgical staging of early stage endometrial cancer

Гладчук, І. З.; Рожковська, Н. М.; Марічереда, В. Г.; Кожаков, В. Л.; Petrovskiy, Yuriy

doi:10.1136/ijgc-2019-esgo.588

Cited by 2 publications

(3 citation statements)

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“…Також є багато досліджень щодо використання методу маркування СЛВ у низьких [41,42] та високих [43,44] групах ризику метастазування. У ретроспективному дослідженні M. Bedyńska [47].…”

Section: рак ендометріяunclassified

Methodology of ICG marking technique in modern pelvic surgery: applied aspects (Literature review)

Gladchuk,

Kiriakova,

Sidak

et al. 2024

RHW

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The article is devoted to a review of scientific publications on the use of the Indocyanine green (ICG) labeling technique in modern pelvic surgery. This dye was developed by Kodak Research Laboratories in 1955 and approved for clinical use in 1959, but has only recently come into widespread use. ICG-enhanced near-infrared fluorescence is introduced to improve visualization and provide more detailed anatomical localization during surgery.The dye binds to blood plasma proteins, it is quickly excreted from the organism and is non-toxic and has no found complications after its administration. Many studies have been conducted on the use of this technique: visualization of sentinel lymph nodes (SLN) in various oncogynecological diseases; visualization of ureters, lymphatic drainage, tissue perfusion, vessels of various sizes, colorectal blood circulation, etc. The high detection rate of SLN (unilateral and bilateral) with ICG compared with other dyes such as radiocolloid and patent blue suggests its effectiveness.The condition of SLN has an important prognostic and therapeutic value, based on the obtained results, a more correct further adjuvant treatment can be prescribed. A sentinel lymph node labeling procedure was performed as an alternative to systemic lymphadenectomy to assess the status of lymphovascular invasion. The use of ICG-marking allows to reduce the risk of intraoperative and postoperative complications. Many experimental studies have been conducted in relation to the assessment of uterine vascularization, preservation of individual vessels, their identification and measurement of blood flow.The article provides data from scientists on the use of the ICG-marking technique in endometrial, cervical, vulva, vaginal, ovarian cancer, as well as in endometriosis and for visualization of the ureters. This technique causes active discussions in the scientific community, requires further research and should be more widely used in various directions of surgical interventions.

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Section: рак ендометріяunclassified

Methodology of ICG marking technique in modern pelvic surgery: applied aspects (Literature review)

Gladchuk,

Kiriakova,

Sidak

et al. 2024

RHW

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“…The combined pathology of the endometrium and myometrium is observed in 40-55% of premenopausal women, while 40% of women with uterine fibroids, adenomyosis, and 80% of women with endometrial hyperplasia (EH) develop abnormal uterine bleeding (AUB) [1].…”

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confidence: 99%

“…The frequency of EH relapses and menstrual dysfunction against the background of combined endometrial and myometrial hyperproliferative pathology after hormonal treatment remains quite high. Given the increased risk of malignancy in premenopause, the issue of early diagnosis and individualized treatment does not lose its relevance [1][2][3][4].…”

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confidence: 99%

A differentiated approach to the management of patients with hyperplastic diseases of the uterus complicated by abnormal uterine bleeding

Lomakina,

Rozhkovska,

Sytnikova

et al. 2023

J Educ Health Sport

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The purpose: to justify a differentiated approach to the management of patients with hyperplastic uterine diseases complicated by abnormal uterine bleeding (AUB) based on the study of the morpho-functional features of the endo- and myometrium. It has been shown that PgR expression is low in patients with combined lesions of the endometrium and myometrium complicated by AMC. The degree of PgR expression has a strong negative correlation with pathological changes of the endometrial-myometrial junction (r=-0.71), which made it possible to consider these criteria in the creation of a differentiated algorithm for the management of patients taking into account clinical and morphological pathogenetic variants of the disease. The use of differentiated approaches to the treatment of patients with combined hyperplastic processes of the uterus, taking into account the clinical and morphological features of the disease, made it possible to reduce the number of recurrences of AMC and achieve a long-term clinical effect in comparison with traditional treatment.

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EP530 Indocyanine green in surgical staging of early stage endometrial cancer

Cited by 2 publications

References 0 publications

Methodology of ICG marking technique in modern pelvic surgery: applied aspects (Literature review)

Methodology of ICG marking technique in modern pelvic surgery: applied aspects (Literature review)

A differentiated approach to the management of patients with hyperplastic diseases of the uterus complicated by abnormal uterine bleeding

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