EP26.22: First trimester 2D and 3D sonographic imaging of facial abnormalities in holoprosencephaly spectrum

Abstract

sonographic evaluation revealed large omphalocele probably with liver involvement. Also it was observed acrania and anencephaly. Fetal chorion villus sampling (CVS) was performed that showed Trisomy 18. In rare cases of Trisomy 18 fetal concominant anencephaly and large omphalocele could be observed.