EP-1566 MR-guided online adaptive radiotherapy: First experience in the UK

Pathmanathan, A.; Bower, L.; Creasey, Helen; Dunlop, A.; Hall, Emma; Hanson, I.; Herbert, T.; Lawes, R.; McQuaid, D.; McNair, H.; Mitchell, A.; Smith, Geoffrey G.; Huddart, Robert; Oelfke, Uwe; Nill, Simeon; Tree, A.

doi:10.1016/s0167-8140(19)31986-3

Cited by 3 publications

(3 citation statements)

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“…One treatment session is relatively also longer compared to conventional external beam radiotherapy, and this longer treatment duration could be a potential barrier for the patient. Each treatment lasts approximately 45 min, which is three to four times longer than conventional external beam radiotherapy ( 22 ).…”

Section: Resultsmentioning

confidence: 99%

“…This enables online adaptive radiotherapy delivery and diagnostic quality imaging simultaneously that allows the visualization of tumor and surrounding organs before, during and after treatment ( 9 , 12 , 16 – 19 ), with potentially higher treatment accuracy, the sparing of healthy tissue and the possibility of hypofractionation (providing the total dose in fewer treatment sessions). These features are expected to deliver real health benefits for patients including better tumor control, fewer side effects, and a shorter treatment course ( 17 , 20 – 22 ). Since MR-Linac’s CE approval in June 2018 and FDA approval in December 2018, the technology has been installed in institutions worldwide ( 23 , 24 ).…”

Section: Introductionmentioning

confidence: 99%

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Problems and Promises of Introducing the Magnetic Resonance Imaging Linear Accelerator Into Routine Care: The Case of Prostate Cancer

et al. 2020

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The new radiotherapy high field, 1.5 Tesla MRI-guided linear accelerator (MR-Linac) is being clinically introduced. Sensing and evaluating opportunities and barriers at an early stage will facilitate its eventual scale-up. This study investigates the opportunities and barriers to the implementation of MR-Linac into prostate cancer care based on 43 semi-structured interviews with Dutch oncology care professionals, hospital and division directors, patients, payers and industry. The analysis was guided by the Non-adoption, Abandonment, Scale-up, Spread, and Sustainability framework of new medical technologies and services. Opportunities included: the acquirement of ( 1 ) advanced MRI-guided radiotherapy technology with ( 2 ) the potential for improved patient outcomes and ( 3 ) economic benefits, as well as ( 4 ) professional development and ( 5 ) a higher hospital quality profile. Barriers included: ( 1 ) technical complexities, ( 2 ) substantial staffing and structural investments, ( 3 ) the current lack of empirical evidence of clinical benefits, ( 4 ) professional silos, and ( 5 ) the presence of patient referral patterns. While our study confirms the expected technical and clinical prospects from the literature, it also reveals economic, organizational, and socio-political challenges.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Problems and Promises of Introducing the Magnetic Resonance Imaging Linear Accelerator Into Routine Care: The Case of Prostate Cancer

et al. 2020

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“…A subsequent ATP shift was applied, if necessary, to account for any positional changes that might have occurred during editing and planning. On average, the MRIgRT workflow lasted 45 min [26] and a breakdown of the mean time for each stage of an ATS pathway can be found in the literature [27] . Additional details of the Unity MR-Linac workflow can be found elsewhere [24] , [28] .…”

Section: Methodsmentioning

confidence: 99%