EP-1122: Patterns of care and outcome in HPV p16+ oropharyngeal squamous cell carcinoma treated at a tertiary hospital

Min, Michael; Gowda, Raghu; Micklem, Jasmine; Roos, de; Penniment, Michael; Rees, G J; Hodge, Jeffrey; Stein, Beth E. Shubin; Taylor, A. G.; Krishnan, S.

doi:10.1016/s0167-8140(15)31240-8

Cited by 1 publication

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“…Figure displays the results of the review process in a PRISMA flowchart. On detailed review of full text articles, many records were ineligible as they were review articles, did not report any TORS salvage cases, the salvage cases were indistinguishable from the primary cases/combined cohort, there were insufficient survival data, reports were only conference abstracts, related to nasopharyngeal carcinoma only, or the reports were superseded by more contemporary publications from the relevant institutions . A total of eight studies met the eligibility criteria and have been presented in the results …”

Section: Resultsmentioning

confidence: 99%

Transoral robotic surgery for recurrent cancers of the upper aerodigestive tract—Systematic review and meta‐analysis

et al. 2020

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Background Transoral robotic surgery (TORS) for recurrent head and neck (H&N) cancer is an emerging but relatively infrequent procedure. Methods Systematic review and meta‐analysis of studies reporting survival data and functional outcomes for patients undergoing TORS for previously treated H&N cancers. Results Eight hundred seventy‐eight records were identified, of which eight were eligible for inclusion, covering 161 cases (range 1‐64). The pooled rates were as follows: 2‐year overall survival 73.8% (4 studies, range 70.6‐75.0, 95% confidence intervals (CI) 65.4 to 81.5, [I2 0.0%, P = 1.0]); 2‐year disease‐free survival 74.8% (4 studies, range 56.2‐92.0, 95% CI 63.3 to 84.8, [I2 36.9%, P = .2]); postoperative hemorrhage 9.3% (4 studies, range 3.3‐13.3, 95% CI 4.7 to 15.1, [I2 0.0%, P = .5]). Conclusions Functional and oncological outcomes are favorable, although the follow‐up is limited in the literature. Larger cohorts with longer follow‐up are needed for definitive conclusions to be drawn.

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