Eosinophilic pustular folliculitis of infancy: A rare diagnosis in children

Abstract

Remember EPFI as a differential diagnosis in children with a rash on the scalp and no effect of antibiotic treatment.

A Dermatitis Mimicker: A Case of Infantile Eosinophilic Pustular Folliculitis

“…3,4 Aggressive treatment is typically unnecessary, because this condition is benign and self-limited and should resolve by age 3 years. 5 The clinical differential diagnosis for the presentation of eosinophillic pustular folliculitis of infancy include erythema toxic neonatorum, transient pustular melanosis, scabies, acropustulosis of infancy, Langerhans cell histiocytosis, as well as bacterial, viral, and fungal infections. 2 Although this case did not have the typical presentation of predominant scalp findings, the histological and laboratory findings of eosinophilic spongiosis with mild peripheral eosinophilia aided in clarifying the diagnosis in this case.…”

“…Topical corticosteroids are sufficient treatment in 90% of cases, and dapsone, erythromycin, and indomethacin have been proposed as treatment for refractory cases 3,4 . Aggressive treatment is typically unnecessary, because this condition is benign and self-limited and should resolve by age 3 years 5 . The clinical differential diagnosis for the presentation of eosinophillic pustular folliculitis of infancy include erythema toxic neonatorum, transient pustular melanosis, scabies, acropustulosis of infancy, Langerhans cell histiocytosis, as well as bacterial, viral, and fungal infections 2 .…”