Eosinophilic panniculitis

Burket, John M.; Burket, Bradley J.

doi:10.1016/s0190-9622(85)80007-4

Cited by 35 publications

(17 citation statements)

References 7 publications

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“…10 of the 46 other cases of EC may have been triggered by drugs: penicillin G [2,4] in 3 cases, ampicillin [2], erythromycin [7], cyclins [11,12], bleomycin [12], chloram bucil [12], local anesthetic [4] and acetyl salicylic acid [4,11], A mechanism mediated by immune com plexes has been suggested for EC [2,9,12,15,16]. Direct IF of involved skin revealed a positive reaction for C3 in the walls of der mal vessels in 4 cases [2,4,16,17] as in our case, and for C3 and IgM along the base ment membrane in 2 cases [7,12], Tests for circulating immune complexes have been performed in 3 cases of EC [2,10,12] but were negative.…”

Section: Discussionmentioning

confidence: 99%

Eosinophilic Cellulitis (Wells’ Syndrome): Ultrastructural Study of a Case with Circulating Immune Complexes

et al. 1988

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A 42-year-old woman was observed during 3 bouts of eosinophilic cellulitis over a 6-year-period. Skin biopsies were taken at each relapse and processed for histological, immunofluorescent and ultrastructural studies. Histologically the eosinophilic infiltrate extended to the deep dermis and the subcutaneous fat. High levels of circulating immune complexes, and complement and IgG deposits around the vessels were detected for as long as the cutaneous lesions lasted. Under the electron microscope eosinophils were numerous, half of them degranulated and some granules had a double cristal core. No injury to the vessel walls was observed. The 3 recurrences occurred respectively after lincomycin, nesdonal, acetyl salicylic acid and pholcodin ingestion and responded to sulfone and steroid therapy.

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Section: Discussionmentioning

confidence: 99%

Eosinophilic Cellulitis (Wells’ Syndrome): Ultrastructural Study of a Case with Circulating Immune Complexes

et al. 1988

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“… Eosinophilic panniculitis, characterized by a prominent infiltration of subcutaneous fat with eosinophils, has been identified in patients with a variety of associated clinical conditions. Burket and Burket reported the first case in 1985 1 . To our knowledge, more than 30 additional patients have been described since this initial case report.…”

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confidence: 84%

Eosinophilic panniculitis: Report of three cases

Liu¹,

Xiao²,

Wang³

et al. 2006

Int J Dermatology

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Eosinophilic panniculitis, characterized by a prominent infiltration of subcutaneous fat with eosinophils, has been identified in patients with a variety of associated clinical conditions. Burket and Burket reported the first case in 1985.1 To our knowledge, more than 30 additional patients have been described since this initial case report. The study of 18 patients with biopsy diagnoses of eosinophilic panniculitis by Winkelmann, et al. in 1986 revealed diverse patterns of systemic disease, including Wells’ syndrome, vasculitis, atopy, and erythema nodosum.2 We report three male patients of eosinophilic panniculitis with various clinical signs, two of whom had history of trauma or tuberculous pleurisy.

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“…Klinik olarak genellikle eritemli subkutan nodüller eklinde kar mza ç kmaktad r. Baz hastal klarla birliktelik bildirilmektedir (1). Burada, altta yatan herhangi bir neden tespit edilemeyen ve dapson tedavisine yan t al nan bir olgu literatür bulgular e li inde sunulmaktad r.…”

Section: Giriunclassified

“…Klinik olarak daha çok bacaklara yerle en hassas nodüler lezyonlar ile karakterize olan bu hastal kta plaklar ile birlikte veziküllerde görülebilir (1). Ancak bizim olgumuzda plaklar ve veziküller yerine sadece eritemli nodüler lezyonlar vard .…”

Section: Tart Maunclassified

Eosinophilic Panniculitis with Full Response to Dapsone Therapy: A Case Report

Aktaş¹,

Taşlıdere²,

Canöz³

2010

Turk J Dermatol

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ÖzetEozinofilik pannikülit subkutan dokuda daha çok eozinofillerin oluşturduğu mikst tipte iltihabi hücre infiltrasyonu ile seyreden bir pannikülittir. Etiyolojide en sık gnathostomiyazis (Larva migrans profondus), lökositoklastik vaskülit ve eritema nodosum suçlanmaktadır. Burada steroid tedavisine yanıt alınamayan ancak dapson tedavisi ile tam olarak düzelen idiyopatik eozinofilik pannikülitli bir olgu sunularak literatür bilgileri gözden geçirilmiştir. (Turk J Dermatol 2010; 4: 94-6 GiriEozinofilik pannikülit, subkutan ya dokusunun yo un olarak eozinofillerden olu an infiltrasyonudur. Klinik olarak genellikle eritemli subkutan nodüller eklinde kar mza ç kmaktad r. Baz hastal klarla birliktelik bildirilmektedir (1). Burada, altta yatan herhangi bir neden tespit edilemeyen ve dapson tedavisine yan t al nan bir olgu literatür bulgular e li inde sunulmaktad r. OlguElli ya nda erkek hasta, be y ld r y lda bir kaç kez tekrarlayan kol ve bacaklarda k zar kl k, i lik ikâyetiyle klini imize ba vurdu. i likler yakla k 20 gün devam edip kendili inden geçiyormu . Dermatolojik muayenesinde; sa kol, sol uyluk ve bacakta eritemli 5-6 cm çap nda nodüler lezyonlar tespit edildi ( ekil 1).Al nan deri biyopsisinde yüzeysel dermiste perivasküler mononükleer hücre infiltrasyonu, subkutan ya doku içerisinde nodüler ve lobüler yer yer septal yerleim gösteren bask n olarak eozinofilleri ayr ca nötrofil ve histiyositleri de içeren mikst tipte iltihabi hücre infiltrasyonu izlendi ( ekil 2). Bulgular eozinofilik pannikülit ile uyumlu olarak de erlendirildi.Hastan n tam kan say m nda hemoglobin: 16.8 g/dl, beyaz küre: 6530 hcr/ L, trombosit: 175.000 /L, kan biyokimyas nda üre: 23.5 mg/dl, kreatinin: 0.9 mg/dl,

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Eosinophilic panniculitis

Cited by 35 publications

References 7 publications

Eosinophilic Cellulitis (Wells’ Syndrome): Ultrastructural Study of a Case with Circulating Immune Complexes

Eosinophilic Cellulitis (Wells’ Syndrome): Ultrastructural Study of a Case with Circulating Immune Complexes

Eosinophilic panniculitis: Report of three cases

Eosinophilic Panniculitis with Full Response to Dapsone Therapy: A Case Report

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