Eosinophilic oesophagitis and coeliac disease: Is there an association?

Quaglietta, Lucia; Coccorullo, P.; Miele, Erasmo; Pascarella, Filomena; Troncone, Riccardo; Staiano, Annamaria

doi:10.1016/j.dld.2007.07.093

Cited by 19 publications

(28 citation statements)

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“…This suggests that CD may be assoc iated with an increased risk of cardiovascular outcome. There may also be an assoc iation between CD and eosinophilic esophagitis [84] . Aldolase B deficiency causes hereditary fructose intoleranc e, and this may be assoc iated with CD [85] .…”

Section: Clinical Associationsmentioning

confidence: 99%

Recent advances in celiac disease

Freeman

Chopra²,

Clandinin³

et al. 2011

WJG

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Celiac disease now affects about one person in a hundred in Europe and North America. In this review, we consider a number of important and exciting recent developments, such as clinical associations, HLA-DQ2 and HLA-DQ8 predispositions, the concept of potential celiac disease, the use of new imaging/endoscopy techniques, and the development of refractory disease. This review will be of use to all internists, pediatricians and gastroenterologists.

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Section: Clinical Associationsmentioning

confidence: 99%

Recent advances in celiac disease

Freeman

Chopra²,

Clandinin³

et al. 2011

WJG

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“…In two studies, children who had undergone repeated endoscopic examinations showed recovery of their duodenal mucosa but no resolution of esophageal eosinophilia on a gluten-free diet alone, as in our case (1,2). However, Quaglietta et al (7) reported that 6 children with CD and EE who primarily had the symptoms of EE had all improved symptomatically on gluten-free diet, and 3 children's second endoscopy showed significant reduction in intraesophageal eosinophils. Studies have also shown that eosinophils may play a role in gliadininduced intestinal damage (8).…”

Section: Discussionmentioning

confidence: 74%

Çölyak hastalığı ve eozinofilik özefajit birlikteliği: Bu iki hastalık için bir tesadüf mü?

Appak¹,

Ayhan²,

Kasırga³

2015

Ege Tıp Dergisi

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Celiac disease and eosinophilic esophagitis are usually considered to be separate gastrointestinal diseases; however, it appears that they may coexist more often than would be expected. We report the case of a 5-year-old girl who had positive celiac serology and was assessed as having type 3c celiac disease according to the Marsh classification with endoscopic pathology. However, the patient's eosinophils were more than 100 per high-power field in esophageal mucosal biopsy specimens and she was evaluated as having eosinophilic esophagitis as well. The relationship between celiac disease and eosinophilic esophagitis is not clear. Nevertheless, coexistence of eosinophilic esophagitis needs to be considered in children with celiac disease.

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“…1,4 An association between EE and CD has previously been described in adult and pediatric reports. 1,6,7 Quaglietta L et al 6 reported CD in six out of 17 pediatric patients (35.2%) with EoE, and stated that histological and clinical improvement were seen after a gluten-free diet. In contrast, an increased prevalence of EoE in patients with CD has also been reported in pediatric patients.…”

Section: T H I S S T U D Y D E S C R I B E S ( I ) T H E C L I N I C mentioning

confidence: 99%