Eosinophilic mastitis: A chameleon disease in rheumatologists' domain

Eosinophilic mastitis: a rare benign inflammatory condition and review of the literature

“…The literature reports the most common clinical features of eosinophilic mastitis include a mobile breast lump often associated with pain, erythema and skin thickening ( Table 1 ). However, two cases also reported nipple discharge [ 16 , 17 ]. Serum eosinophilia was present in all but one case [ 18 ], whereas only two cases of the disease were reported in patients without a history of asthma or allergic rhinitis [ 9 , 18 ].…”

“…One case reported a missed eosinophilic mastitis on initial fine needle aspirate [ 16 ]. Histologically, eosinophilic mastitis is characterized by periductal, interlobular and interstitial infiltration by eosinophils often with ductal dilatation and accompanying fibrosis and epithelial cell atypia or reactive hyperplasia [ 17 ].…”

“…In Bang’s case study, successful resolution was achieved with a daily dose of 60 mg of prednisolone, titrated over 5 months [ 26 ]. Comparatively, effective treatment with anti-histamines alone has been reported [ 27 ], as well as in conjunction with steroid therapy [ 17 ]. Our approach utilized a judicious use of systemic steroids with an initial dose of 25 mg of prednisolone per day for a period of just 5 days, titrating the dose over a further 7 days.…”

Eosinophilic mastitis in a lactating breast

“…Knowledge of the lesion and early diagnosis can avoid unnecessary surgical intervention. 1 Herein reported is a case of eosinophilic mastitis presenting 4 months post-partum, in a breast feeding individual. To our knowledge this is the first case of eosinophilic mastitis described in a lactating breast.…”

Eosinophilic mastitis mimicking a developing asymmetry

“…It can present as a developing asymmetry that can be radiologically ambiguous and may warrant further evaluation, as seen in this patient. Detection and identification of eosinophilic mastitis is important because accepting the benign histology as “concordant” after biopsy can prevent unnecessary surgical intervention and the complications that surgery may provide [2] . This is a case of a patient with a developing asymmetry in her right breast over several years that was eventually diagnosed as eosinophilic mastitis.…”