Eosinophilic Liver Abcesses and Pyrexia of Unknown Origin in Idiopathic Hypereosinphilic Syndrome: Myeloproliferative or Mimic?

Abstract

We report a case which presented with pyrexia of unknown origin ( P UO) with eosinophilia and multiple hypoechoic lesions in the liver resembling secondaries. After secondary causes were ruled out, aspiration of liver lesions revealed eosinophilic abcesses. A diagnosis of idiopathic hypereosinophilic syndrome (HES) was made and the patient responded to steroid therapy. HES remains a diagnosis of exclusion. HES presenting with PUO and liver abcesses is very rare. A high index of suspicion is required to recognize the involvement of different organ systems due to HES.