Eosinophilic granuloma of the cervicothoracic junction

Sweasey, Thomas A.; Dauser, Robert C.

doi:10.3171/jns.1989.71.6.0942

Cited by 34 publications

(32 citation statements)

References 12 publications

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“…The most common complaint at presentation is pain [2,7,10,11], often worse at night [2,7,10]. In case of vertebral involvement, neurological signs and symptoms due to cord or nerve root compression may occur [2,3,8,11].…”

Section: Discussionmentioning

confidence: 98%

Limp as unusual presentation of Langerhans' cell histiocytosis

Bodart

Nisolle

Maton

et al. 1999

European Journal of Pediatrics

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Section: Discussionmentioning

confidence: 98%

Limp as unusual presentation of Langerhans' cell histiocytosis

Bodart

Nisolle

Maton

et al. 1999

European Journal of Pediatrics

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“…Obwohl viele Behandlungsmöglichkei-ten wie Biopsie, intraläsionale Kürettage, En-bloc-Resektion, Strahlentherapie [33], Chemotherapie [20] …”

Section: > Eine Chirurgische Behandlung Ist Bei Lh Selten Indiziertunclassified

Wirbelsäulenerkrankungen im Kindesalter

Kafchitsas

Vetter

Kurth

2010

Monatsschr Kinderheilkd

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Leitthema Der Wirbelsäule kommt als Achsenorgan eine besondere Bedeutung im Bewegungsapparat zu. Sie nimmt an nahezu allen Bewegungen des Kör-pers teil. Ihre Form und Haltung bilden sich mit der Entwicklung des Menschen aus. So verliert das Kind die embryonale kyphotische Wirbelsäulenhaltung erst mit dem Krabbeln und insbesondere mit dem Beginn des Laufens durch Herausbildung einer Lordose. Die Wirbelsäulenerkrankungen im Kindesalter beinhalten ein sehr großes Spektrum an Krankheiten und Syndromen, die den Rahmen des vorliegenden Beitrags sprengen würden. In ihm werden die häufigsten Krankheitsbilder angesprochen, deren Diagnose den behandelnden Arzt vor die Entscheidung zur oder gegen eine Operation stellt. Skoliose DefinitionUnter einer echten Skoliose wird die nicht vollständig korrigierbare Seitverbiegung der Wirbelsäule mit Rotation verstanden [24]. Dabei müssen strukturelle, also die Form der Wirbel betreffende Veränderun-gen vorliegen. Insgesamt sind diese als Folge der Seitverbiegung und Rotation der skoliotischen Wirbelsäule zu verstehen.

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“…The cervical lesion commonly appears as a lytic lesion involving the vertebral body with preserved disc spaces 10 , nevertheless, atypic cases involve erosion or destruction of pedicles and posterior elements 5,13 . Although the vertebral affection was frequently reported, the involvement of the spinal cord and of the roots is rarely discussed in the literature.…”

Section: Fig 3 Histopathological Study Prepared Antibody Protein Anmentioning

confidence: 99%

“…Such pathological entities have in common a histopathological characteristic pattern of histiocytary nature (Langerhans cells) associated with eosinophils [1][2][3][4][5][6][7][8][9][10] .…”

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confidence: 99%

Cervical spine cord compression by eosinophilic granuloma: case report

Duarte-Silva

Noujaim

Carnevale

1999

Arq. Neuro-Psiquiatr.

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-Eosinophilic granuloma is a term reserved for the most often and benign form of disorder known as Langerhans cells histiocytosis. It is a disease of children and adolescents that very rarely affects adults, representing the localized form of a pathological proliferation of histiocytes in bones, like skull and long bones. Vertebral involvement is uncommon, approximately 8% of the cases, being the cervical localization the least affected. Moreover, the involvement of the spinal cord and roots remains a rare occurrence. Only five cases characterized by signs of cervical spinal cord compression have been reported. We report the sixth case in a 42-year-old-man who evolved with resolution of symptoms, and has remained asymptomatic after treatment. The clinical, radiological and histological features and, also, the value, in selected cases, of surgical treatment followed by low-dose radiation therapy is discussed. A review of the pertinent literature is also presented.KEY WORDS: cervical eosinophilic granuloma, cervical spinal cord compression, Langerhans cells histiocytosis. Compressão medular cervical por granuloma eosinofílico: relato de casoRESUMO -Granuloma eosinofílico é um termo reservado para a forma mais frequente e benigna da enfermidade conhecida como histiocitose das células de Langerhans. É uma doença de crianças e adolescentes, muito raramente afetando adultos, representando a forma localizada de uma proliferação patológica de histiócitos em ossos, crânio e ossos longos. O acometimento vertebral é incomum, aproximadamente 8% dos casos, sendo a localização cervical a menos descrita. Além disso, o acometimento da medula espinhal e das raízes é de rara ocorrência. Na literatura foram relatados apenas cinco casos caracterizados por sinais de compressão medular cervical. Relatamos o sexto caso, de um homem de 42 anos de idade que evoluiu com regressão dos sintomas após tratamento, tendo permanecido assintomático. As características clínicas, radiológicas, histopatológica e o valor, em casos selecionados, do tratamento cirúrgico seguido de radioterapia em baixas doses são discutidos. Revisão da literatura pertinente também é apresentada. PALAVRAS-CHAVE: granuloma eosinofílico cervical, compressão medular cervical, histiocitose das células de Langerhans.The term eosinophilic granuloma was introduced in 1940 by Jaffe and Lichtenstein 1 in order to describe an isolated bone tumour, and also to nominate the most benign form of histiocytosis X or, more recently 2 , Langerhans cells histiocytosis, which is a generic term that includes two uncommon diseases: Hand-Schuller-Christian and Letterer-Siwe diseases. Such pathological entities have in common a histopathological characteristic pattern of histiocytary nature (Langerhans cells) associated with eosinophils 1-10 .

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Eosinophilic granuloma of the cervicothoracic junction

Cited by 34 publications

References 12 publications

Limp as unusual presentation of Langerhans' cell histiocytosis

Limp as unusual presentation of Langerhans' cell histiocytosis

Wirbelsäulenerkrankungen im Kindesalter

Cervical spine cord compression by eosinophilic granuloma: case report

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