Eosinophilic fasciitis: A case report

Correa, Amalia Londoño; Londoño, Ángela; Ruíz, Ana Cristina; Mesa, Mónica

doi:10.1016/j.rcreue.2018.07.001

Cited by 3 publications

(11 citation statements)

References 43 publications

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“…9,12,13 The pathophysiology of EF has not been elucidated but is thought to be related to the overactivation of eosinophils that release transforming growth factors. 13 Related manifestations include weight loss, fatigue, myalgias, and carpal tunnel syndrome. 12,13 The physical examination will demonstrate the skin changes discussed above typically involving the extremities, excluding the hands and feet.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…13 Related manifestations include weight loss, fatigue, myalgias, and carpal tunnel syndrome. 12,13 The physical examination will demonstrate the skin changes discussed above typically involving the extremities, excluding the hands and feet. 12 The "groove sign" differentiates EF from other sclerotic diseases, demonstrating linear induration following the path of superficial vasculature.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…12 The percentage of peripheral eosinophils will be markedly elevated in laboratory work. 12,13 A skin biopsy will demonstrate fibrosis and invasion of lymphocytes and eosinophils into the dermis, subcutaneous tissue, and superficial fascia along with fascial thickening. 9,13 Another disease-defining feature of EF is its marked improvement after treatment with pulse dose steroids.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…Eosinophilic fasciitis (EF) is characterized by edematous, erythematous skin progressing to hardened, woody skin, and finally to underlying fascial tightening 9,12,13 . The pathophysiology of EF has not been elucidated but is thought to be related to the overactivation of eosinophils that release transforming growth factors 13 . Related manifestations include weight loss, fatigue, myalgias, and carpal tunnel syndrome 12,13 .…”

Section: Differential Diagnosismentioning

confidence: 99%

See 3 more Smart Citations

Boosting Awareness of Sclerotic Skin Diseases: Exploring the Inflammatory Overlap of Sclerotic Skin Disease and COVID‐19 Vaccination

Anstett,

Reginato,

Elco

et al. 2023

Arthritis Care & Research

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A 77-year-old female presented to the rheumatology clinic for evaluation of an expansive, tightened skin plaque (Figure 1). The changes began 1 week after receiving the Moderna COVID-19 vaccination; otherwise, she had no changes in medications or lifestyle. Six months prior to her presentation, she went to her dermatologist who performed a biopsy with histologic findings suggestive of morphea (Figure 2). Initially, systemic treatment with mycophenolate was offered, but she declined at the time. Unfortunately, over the next 6 months, the lesion expanded across the trunk and back, becoming pruritic and thickened. Because of disease progression, she presented to rheumatology for further evaluation and treatment.

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Section: Differential Diagnosismentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

See 2 more Smart Citations

Boosting Awareness of Sclerotic Skin Diseases: Exploring the Inflammatory Overlap of Sclerotic Skin Disease and COVID‐19 Vaccination

Anstett,

Reginato,

Elco

et al. 2023

Arthritis Care & Research

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“…Su etiología no está clara: probablemente sea autoinmune. En un 30-40 % de casos puede haber factores desencadenantes 2 . Hay unos 300 casos reportados desde 1974, cuando fue descrita por Shulman 2,6 .…”

Section: Comentariosunclassified

Cuando unos edemas no son lo que parecen

Fornés Ollé,

Boada Peiró,

Cuberas Mas

et al. 2023

Med Gen Fam

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Historia del artículo:Recibido el 24 de octubre de 2022 Aceptado el 30 de abril de 2023On-line el 7 de mayo de 2023 La fascitis eosinofílica es una patología poco frecuente del tejido conectivo de etiología desconocida que requiere de un rápido diagnóstico porque el pronóstico mejora si se inicia el tratamiento precozmente y porque un 10 % puede asociarse a enfermedades hematooncológicas.Debemos sospechar la presencia de una fascitis eosinofílica ante un cuadro de eritema y edema generalizado en las extremidades, que no responde a diuréticos, que progresa a induración de la piel, acompañado de dolor y rigidez articular, eosinofilia periférica, elevación de reactantes de fase aguda e hipergammaglobulinemia.Procede remitir a Dermatología de forma urgente para confirmar mediante biopsia profunda de la piel y así iniciar tratamiento precoz con immunosupresores para lograr un curso más favorable y con menos secuelas articulares.

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Eosinophilic Fasciitis Presenting as Chronic Nonspecific Symptoms in a Young Adult

Khaleel,

Ayyad,

Khalil

et al. 2023

Oxford Medical Case Reports

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Eosinophilic fasciitis (EF) is a rare inflammatory disease affecting various connective tissues. It is characterized by induration of the skin as well as scleroderma-like manifestations that are progressive and bilaterally symmetrical. Additionally, the joints and muscles are commonly involved, and rarely, there can be involvement of internal organs. The diagnosis of EF is based on clinical, laboratory, radiological, and a full-thickness skin biopsy involving the fascia. The biopsy is often diagnostic and shows eosinophilic inflammation. Systemic corticosteroids specifically prednisone and prednisolone remain the preferred treatment of choice and may be combined with immunosuppressive therapy in a subset of patients. We herein report a patient complaining of chronic nonspecific symptoms that were diagnosed with EF. The patient was treated with steroids with marked improvement of his overall condition.

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Eosinophilic fasciitis: A case report

Cited by 3 publications

References 43 publications

Boosting Awareness of Sclerotic Skin Diseases: Exploring the Inflammatory Overlap of Sclerotic Skin Disease and COVID‐19 Vaccination

Boosting Awareness of Sclerotic Skin Diseases: Exploring the Inflammatory Overlap of Sclerotic Skin Disease and COVID‐19 Vaccination

Cuando unos edemas no son lo que parecen

Eosinophilic Fasciitis Presenting as Chronic Nonspecific Symptoms in a Young Adult

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