2006
DOI: 10.1159/000093847
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Eosinophilic Fasciitis 30 Years after – What Do We Really Know?

Abstract: Background: Eosinophilic fasciitis (EF) is a rare fibrosing disorder associated with peripheral eosinophilia and scleroderma-like induration of the distal extremities which affects substantially quality of life. Although the disease has been described 30 years ago, the etiology and pathomechanisms are still obscure, and consensus for therapy is lacking. Numerous case reports of patients with EF exist but series are scarce. Patients and Methods: Eleven patients with EF from the Department of Dermatology, Kanton… Show more

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Cited by 109 publications
(58 citation statements)
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References 82 publications
(79 reference statements)
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“…Eosinophilic fasciitis or Shulman syndrome is another rare entity usually presenting with bilateral swelling of the extremities, followed by peau d’orange changes and finally woody induration, thickening and tightness of the skin [9,10]. Retraction of the superficial veins within the indurated skin results in linear depressions described as the ‘groove sign’.…”
Section: Discussionmentioning
confidence: 99%
“…Eosinophilic fasciitis or Shulman syndrome is another rare entity usually presenting with bilateral swelling of the extremities, followed by peau d’orange changes and finally woody induration, thickening and tightness of the skin [9,10]. Retraction of the superficial veins within the indurated skin results in linear depressions described as the ‘groove sign’.…”
Section: Discussionmentioning
confidence: 99%
“…A maioria dos pacientes se encontra entre a terceira e sexta década de vida, mas o acometimento da população pediátrica também tem sido relatado. 2 A etiologia da FE é desconhecida. Alguns estudos sugerem que doenças auto-imunes, hematológicas, infecciosas, fármacos, traumatismos, esforço físico intenso ou picadas de inseto podem ser fatores associados e desencadeadores da doença, 3 mas não foi identificado nenhum destes fatores no presente caso.…”
Section: Caso Clínicounclassified
“…simvastatin [7] , atorvastatin [8] , lansoprazol [9] , phenytoin [10] ), myeloproliferative illnesses [11] , thyroid diseases [12] , extreme physical activity, bone marrow transplantation [13] , haemodialysis [14] and arthropod bites have all been described as causative agents.…”
Section: (2005)mentioning
confidence: 99%