Eosinophilic Esophagitis Disease in Children from West Virginia: A Review of the Last Decade (1995?2004)

Gill, Rupa; Durst, Paul; Rewalt, Mary; Elitsur, Yoram

doi:10.1111/j.1572-0241.2007.01352.x

Cited by 68 publications

(78 citation statements)

References 18 publications

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“…Overall, EoE was found in 4.2% of all children undergoing EGD in this retrospective review, comparable to previous rates of 3% and 5% [7,11]. The rate of EoE by symptom in decreasing order was dysphagia (18.1%), food bolus impaction (8.1%), vomiting (5.0%), dyspepsia (4.3%), gastroesophageal reflux (4.0%), and abdominal pain (2.2%).…”

Section: Discussionsupporting

confidence: 68%

Influence of gender and race on presentation of eosinophilic esophagitis in children

Nguyen¹,

Bishop²,

Nowicki³

2013

OJPed

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Background: Eosinophilic esophagitis (EoE) is thought to be more common in males and Caucasians, yet little data exists regarding the presentation of EoE among children. Methods: A retrospective study of children undergoing esophagogastroduodenoscopy (EGD) was done to determine gender and racial differences in the prevalence and presenting symptoms of EoE. Data collected included gender, race, indication for EGD, and presence of EoE. Results: No gender or racial differences were found for indication for EGD. EoE was identified in 4.1% of children, more commonly in males than females (6% vs. 2.5%, p < 0.01). No racial difference was seen. Symptoms showing a racial/gender difference included dysphagia, vomiting, and foreign body impaction. Conclusions: Prevalence of EoE differs by gender, but not race. Gender/racial differences exist for EoE in children presenting with dysphagia, vomiting, and foreign body impaction. This data may help guide the clinician on when to refer for EGD.

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Section: Discussionsupporting

confidence: 68%

Influence of gender and race on presentation of eosinophilic esophagitis in children

Nguyen¹,

Bishop²,

Nowicki³

2013

OJPed

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“…1,6 While the epidemiology of EoE has been better described in the paediatric population, a number of studies have attempted to examine the prevalence of EoE in adults. 7,8 Recently, a systematic review, that assessed the epidemiology of EoE among adults, have identified nine studies with over 100 000 individuals. 9 The reported prevalence rates of EoE in these studies varied widely from 0.02% to 48.2%.…”

Section: Resultsmentioning

confidence: 99%

The 2011–2014 prevalence of eosinophilic oesophagitis in the elderly amongst 10 million patients in the United States

Maradey–Romero

Prakash

Lewis

et al. 2015

Aliment Pharmacol Ther

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“…By the end of 2003, a prevalence rate of 43 per 100,000 children was reached in the pediatric population of Hamilton County, with a substantial increase in the years 2000-2003 [10]. Other studies on retrospective review of upper endoscopy procedure or histopathology reports of children also describe increasing prevalence rates during the last years [11,12,13,14]. In a prospective evaluation of children and infants in Southern Denmark (pediatric population of 256,164; age: 0-16 years) with symptoms of gastroesophageal reflux disease during an 18-month period, 6 patients were diagnosed with EoE, corresponding to an annual incidence rate of 1.6 per 100,000 children [15].…”

Section: Incidence and Prevalence Of Eoe Based On Endoscopy And Histomentioning

confidence: 99%

“…Children may present with a variety of symptoms. In addition to dysphagia and bolus obstruction, feeding disorder, failure to thrive, abdominal pain, heartburn and vomiting may occur [10,13,36,37]. Food impaction and/or the necessity for bolus removal ranges between 30 and 50% in most studies [20,26,28,29,38].…”

Section: Symptoms Of Esophageal Dysfunctionmentioning

confidence: 99%

Epidemiology of Eosinophilic Esophagitis

Hrúz¹

2014

Dig Dis

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Eosinophilic esophagitis (EoE) is an allergy-associated disease defined clinically by esophagus-related symptoms in combination with a dense esophageal eosinophilia, both of which are unresponsive to prolonged acid suppression with proton pump inhibitors. Over the last two decades EoE has increasingly been recognized in various geographical areas (mostly industrialized countries) with high socioeconomic development. The prevalence rate is increasing and reaches up to 50 patients per 100,000 inhabitants in some indicator regions. Whether this increased prevalence is due to a real increase in incidence, a result of increased awareness by health care providers or because of the nonfatal nature of EoE adding more and more cases to the patient pool is still a matter of controversy. Several studies have consistently demonstrated a male predominance in EoE, with a male-to-female risk ratio of 3:1. The average age at diagnosis ranges between 30 and 50 years and suggests that EoE is a disease of the middle-aged man. It can affect patients of every race, but the disease is more common among Caucasians. In both children and adults, EoE has been clearly associated with allergies to food and aeroallergens, and most EoE patients present with a personal allergic background (e.g. asthma, rhinoconjunctivitis or oral allergy syndrome). In conclusion, knowledge of epidemiologic parameters of EoE is crucial for identifying risk factors as well as pathogenic mechanisms, planning preventive measures and determining optimal treatment strategies.

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Eosinophilic Esophagitis Disease in Children from West Virginia: A Review of the Last Decade (1995?2004)

Abstract: The rate of EoE in our pediatric patient population is low. Prospective studies are needed to establish the incident and prevalence of EoE disease in children living in the United States.

Cited by 68 publications

References 18 publications

Influence of gender and race on presentation of eosinophilic esophagitis in children

Influence of gender and race on presentation of eosinophilic esophagitis in children

The 2011–2014 prevalence of eosinophilic oesophagitis in the elderly amongst 10 million patients in the United States

Epidemiology of Eosinophilic Esophagitis

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