Enzymes in jasmonate biosynthesis – Structure, function, regulation

Schaller, Andreas; Stintzi, Annick

doi:10.1016/j.phytochem.2009.07.032

Cited by 348 publications

(294 citation statements)

References 82 publications

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“…1). The BIN 26 representing 'Misc' group comprised most transcripts (58) with genes related to oxidases, peroxidase, GST, cytochrome P450, etc. The transcripts identified to mediate amino acid metabolism (39), protein related (39), transport (38), stress (24) and signaling related transcripts (23) comprised other major groups.…”

Section: Overview Of Greenbug Induced Transcriptomic Changesmentioning

confidence: 99%

“…Initial steps in JA biosynthesis, generating 12-oxophytodienoic acid (OPDA) from a-linolenic acid (a-LeA) is mediated by lipoxygenase (LOX) genes in chloroplast [58,59]. The transitional steps involving release of OPDA from walls of plastids and uptake by peroxisomes remain obscure while the later steps in JA biosynthesis are catalyzed by OPDA reductase (OPR) and are localized to peroxisomes [58,59].…”

Section: Phytohormone Signaling and Transcriptional Regulationmentioning

confidence: 99%

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Transcriptomics of induced defense responses to greenbug aphid feeding in near isogenic wheat lines

et al. 2013

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Section: Overview Of Greenbug Induced Transcriptomic Changesmentioning

confidence: 99%

Section: Phytohormone Signaling and Transcriptional Regulationmentioning

confidence: 99%

Transcriptomics of induced defense responses to greenbug aphid feeding in near isogenic wheat lines

et al. 2013

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“…Biosynthesis of JAs starts with release of linolenic acid from chloroplast membranes and is mediated by JA biosynthetic enzymes, including phospholipase A1-type lipases, lipoxygenase, allene oxide synthase, allene oxide cyclase, and 12-oxophytodienoic acid reductase (Wasternack, 2007;Schaller and Stintzi, 2009). Mutants for ALLENE OXIDE SYNTHASE (AOS) or 12-OXOPHYTODIENOIC ACID REDUCTASE3 (OPR3)/ DELAYED DEHISCENCE1 have defects in endogenous JA production and reduced growth inhibition in response to wounding (Sanders et al, 2000;Stintzi and Browse, 2000;Park et al, 2002;Yan et al, 2007;Zhang and Turner, 2008).…”

Section: Introductionmentioning

confidence: 99%

A bHLH-Type Transcription Factor, ABA-INDUCIBLE BHLH-TYPE TRANSCRIPTION FACTOR/JA-ASSOCIATED MYC2-LIKE1, Acts as a Repressor to Negatively Regulate Jasmonate Signaling inArabidopsis

et al. 2013

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Jasmonates (JAs) are plant hormones that regulate the balance between plant growth and responses to biotic and abiotic stresses. Although recent studies have uncovered the mechanisms for JA-induced responses in Arabidopsis thaliana, the mechanisms by which plants attenuate the JA-induced responses remain elusive. Here, we report that a basic helix-loophelix-type transcription factor, ABA-INDUCIBLE BHLH-TYPE TRANSCRIPTION FACTOR/JA-ASSOCIATED MYC2-LIKE1 (JAM1), acts as a transcriptional repressor and negatively regulates JA signaling. Gain-of-function transgenic plants expressing the chimeric repressor for JAM1 exhibited substantial reduction of JA responses, including JA-induced inhibition of root growth, accumulation of anthocyanin, and male fertility. These plants were also compromised in resistance to attack by the insect herbivore Spodoptera exigua. Conversely, jam1 loss-of-function mutants showed enhanced JA responsiveness, including increased resistance to insect attack. JAM1 and MYC2 competitively bind to the target sequence of MYC2, which likely provides the mechanism for negative regulation of JA signaling and suppression of MYC2 functions by JAM1. These results indicate that JAM1 negatively regulates JA signaling, thereby playing a pivotal role in fine-tuning of JA-mediated stress responses and plant growth.

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“…In plants, jasmonates (JAs) form a group of oxylipins (oxygenated fatty acids) produced via the octadecanoid pathway (for review, see Balbi and Devoto, 2008;Schaller and Stintzi, 2009;Wasternack and Kombrink, 2010). The volatile phytohormone methyl jasmonate (MeJA), produced through the activity of JA carboxyl methyltransferase (Seo et al, 2001), is an easy-tohandle JA conjugate extensively used in biological assays (Staswick et al, 1992;Pauwels et al, 2008).…”

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confidence: 99%

Jasmonate Controls Leaf Growth by Repressing Cell Proliferation and the Onset of Endoreduplication while Maintaining a Potential Stand-By Mode

et al. 2013

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Phytohormones regulate plant growth from cell division to organ development. Jasmonates (JAs) are signaling molecules that have been implicated in stress-induced responses. However, they have also been shown to inhibit plant growth, but the mechanisms are not well understood. The effects of methyl jasmonate (MeJA) on leaf growth regulation were investigated in Arabidopsis (Arabidopsis thaliana) mutants altered in JA synthesis and perception, allene oxide synthase and coi1-16B (for coronatine insensitive1), respectively. We show that MeJA inhibits leaf growth through the JA receptor COI1 by reducing both cell number and size. Further investigations using flow cytometry analyses allowed us to evaluate ploidy levels and to monitor cell cycle progression in leaves and cotyledons of Arabidopsis and/or Nicotiana benthamiana at different stages of development. Additionally, a novel global transcription profiling analysis involving continuous treatment with MeJA was carried out to identify the molecular players whose expression is regulated during leaf development by this hormone and COI1. The results of these studies revealed that MeJA delays the switch from the mitotic cell cycle to the endoreduplication cycle, which accompanies cell expansion, in a COI1-dependent manner and inhibits the mitotic cycle itself, arresting cells in G1 phase prior to the S-phase transition. Significantly, we show that MeJA activates critical regulators of endoreduplication and affects the expression of key determinants of DNA replication. Our discoveries also suggest that MeJA may contribute to the maintenance of a cellular "stand-by mode" by keeping the expression of ribosomal genes at an elevated level. Finally, we propose a novel model for MeJA-regulated COI1-dependent leaf growth inhibition.

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Enzymes in jasmonate biosynthesis – Structure, function, regulation

Cited by 348 publications

References 82 publications

Transcriptomics of induced defense responses to greenbug aphid feeding in near isogenic wheat lines

Transcriptomics of induced defense responses to greenbug aphid feeding in near isogenic wheat lines

A bHLH-Type Transcription Factor, ABA-INDUCIBLE BHLH-TYPE TRANSCRIPTION FACTOR/JA-ASSOCIATED MYC2-LIKE1, Acts as a Repressor to Negatively Regulate Jasmonate Signaling inArabidopsis

Jasmonate Controls Leaf Growth by Repressing Cell Proliferation and the Onset of Endoreduplication while Maintaining a Potential Stand-By Mode

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