“…Biomimetic sensors (or enzymeless biosensors) are based on the use of synthetic analogues of natural enzymes [9,10], and result from attempts to produce chemical sensors that are more stable and durable than conventional biosensors based on biological materials such as enzymes or antibodies. These devices aim to overcome limitations of conventional enzymatic biosensors, such as availability, cost and enzyme instability, as well as to improve electronic transfer between electrode/active site (biomimetic catalyst/substrate), since in *Address correspondence to this author at the Departamento de Química Analítica -IQ, Universidade Estadual Paulista,14801-970 Araraquara-SP, Brazil; Tel: +55-16330-16620; E-mail: mpilar@iq.unesp.br biomimetic sensors the "active site" is free, in contrast to enzymes, where the active site is surrounded by a dense layer of residual amino acids [9,10].…”