Enzyme formation during solid‐substrate fermentation in rotating vessels

Silman, Robert W.

doi:10.1002/bit.260220213

Cited by 50 publications

(14 citation statements)

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“…The rotation rate of the drum is an important process variable, especially because of shear sensitivity during fungal growth (Silman, 1980;Stuart et al, 1998). We conducted several simulations and showed, in agreement with our expectations, that mixing progress depends little on the rotation speed (in the range of rotation rates considered here), but mainly on the number of rotations made (Fig.…”

Section: Evaluation Of the Mixing Performance In A Rotating Drumsupporting

confidence: 79%

Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter

Schutyser

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Weber

et al. 2001

Biotech & Bioengineering

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A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale-up of mixed solid-state fermenters.

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Section: Evaluation Of the Mixing Performance In A Rotating Drumsupporting

confidence: 79%

Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter

Schutyser

Padding

Weber

et al. 2001

Biotech & Bioengineering

View full text Add to dashboard Cite

show abstract

“…While most of the researchers have used a low mixing speed (1-15 rpm), some have used high rates of rotation. Different results have been reported by different authors (Silman, 1980;Kargi and Curme, 1985;Lonsane, 1987, 1988;Mitchell et al, 1988;Lonsane et al, 1992b). Therefore, it is necessary to study agitation and analyze its effects particularly for a determinate process.…”

Section: Effect Of Different Mixing Interval On Xylanase Productionmentioning

confidence: 98%

Governing parameters on xylanase production using developed bioreactor

Lee¹,

Demirtaş²,

Omar³

2015

MJM

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Aims: Chemicals bleaching are common steps in pulp and paper manufacturing process. The reduction of chemical use would result in lower waste treatment costs while minimizes the impact on the environment. This can be achieved using enzyme (xylanase). Compared to submerged fermentation process, the cost for enzyme production is much cheaper using solid state fermentation process (SSF). The present study aimed to examine factors affect xylanase production using developed SSF bioreactor. Methodology and results:The performance of developed bioreactor namely FERMSOSTAT had been investigated in xylanase production studies. In this studies, local isolate Aspergillus niger USM AI 1 was used together with sugarcane bagasse and palm kernel cake (ratio 1:1), which serve as substrates for xylanase production. The highest xylanase activity and production of 397 U/g and 103 U/mgG glucosamine were obtained, respectively when the fermentation process was carried out under examined enzyme production conditions of 0.5 kg substrate; 70% (w/w) moisture content; 30 °C; aeration at 4 L/h.g fermented substrate for 5 min and mixing at 0.5 rpm for 5 min. On the other hand, compared to initial SSF conditions for xylanase production, xylanase activity increased 681% after all factors affect xylanase production have been examined. Conclusion, significance and impact of study: The performance of the newly developed bioreactor is good since it can be used to produce xylanase with high title when compared with previous researcher findings.

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“…Takamine (1914) proposed the use of rotating drums in place of the static tray fermenters. This modification was to be later adopted for other solid-state fermentation systems (Silman, 1980;Pandey, 1991). After Takamine's investigations, few studies on fungal amylase production on solid media were described during two decades.…”

Section: Amylasesmentioning

confidence: 99%