Enzyme biosensor systems based on porous silicon photoluminescence for detection of glucose, urea and heavy metals

Syshchyk, Olga; Skryshevsky, V. A.; Солдаткін, О. О.; Солдаткин, А. П.

doi:10.1016/j.bios.2014.10.075

Cited by 107 publications

(57 citation statements)

References 34 publications

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“…Typically, Cu 2+ at a low dose (<0.9 mg/day) is an indispensable trace nutrient. However, excess Cu 2+ accumulation is poisonous to humans in that it can often cause neurodegenerative diseases probably by its involvement in the generation of active oxygen species 4,5. Accordingly, the permissible limit toward Cu 2+ in drinking water is 1.0 ppm (∼20 µM) recommended by U.S. Environmental Protection Agency 6.…”

Section: Methodsmentioning

confidence: 99%

“…Recently, different methods and schemes have been reported for quantitative monitoring of Cu 2+ level, e.g., by spectroscopy 4, electrochemistry 7, inductively coupled plasma mass spectrometry 8, glucometer 9, and colorimetric method 10. Among these methods, electrochemical sensors have a unique place in determination of trace materials due to simplicity, sensitivity, portability and ease of operation 11.…”

Section: Methodsmentioning

confidence: 99%

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Click‐Conjugation of Nanogold‐Functionalized PAMAM Dendrimer: Toward a Novel Electrochemical Detection Platform

et al. 2015

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This work reports a new electrochemical monitoring platform for sensitive detection of Cu2+ coupling click chemistry with nanogold‐functionalized PAMAM dendrimer (AuNP‐PAMAM). The system involved an alkyne‐modified carbon electrode and an azide‐functionalized AuNP‐PAMAM. Initially, the added Cu2+ was reduced to Cu+ by the ascorbate, and then the azide‐modified AuNP‐PAMAM was covalently conjugated to the electrode via Cu+‐catalyzed azide‐alkyne click reaction. The carried AuNPs accompanying PAMAM dendrimer could be directly monitored by stripping voltammetry after acidic pretreatment. By introduction of high‐loading PAMAM dendrimer with gold nanoparticles, as low as 2.8 pM Cu2+ (ppt) could be detected, which was 125‐fold lower than that of gold nanoparticle‐based labeling strategy. The method exhibited high specificity toward target Cu2+ against other potentially interfering ions, and was applicable for monitoring Cu2+ in drinking water with satisfactory results.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Click‐Conjugation of Nanogold‐Functionalized PAMAM Dendrimer: Toward a Novel Electrochemical Detection Platform

et al. 2015

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“…In recent years, the PSi microarray has been researched and studied all over the world. Syshchyk et al [16] enhanced the reflectance spectra of multilayer porous silicon for the 33-array detection of human immunoglobulin G to be achieved. In contrast, the experimentation failed to achieve high-throughput chip detection.…”

Section: Introductionmentioning

confidence: 99%

Parallel Detection of Refractive Index Changes in a Porous Silicon Microarray Based on Digital Images

Jia

et al. 2017

Sensors

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A new technique for the refractive index change with high-sensitivity measurements was proposed by the digital image of porous silicon (PSi) microarray utilization in this paper. Under the irradiation of a He-Ne laser, the surface images of the PSi array cells with the microcavity structure were obtained by the digital imaging equipment, whereas the refractive index change of each array cells was detected by calculating the average gray value of the image and the refractive index change measurement sensitivity was 10−4 order of magnitude. This technique could be utilized in the label-free and parallel detection of refraction index changes induced by a biological reaction in the microarray or the chip.

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“…The surface of SiNCs containing silicon hydride groups could readily react with 1-ene compounds to form relatively stable Si-C bonds, 5,6 introducing organic functional groups on the surface, facilitating the covalent attachment of organic and biological moieties that open the potential of such inorganic nano-materials to many biological applications. 1,4,7,8 Since the discovery of the PL of SiNCs at room temperature in 1990, 9 the mechanism of the PL generation has been the centre of many studies. Various theories have been proposed in order to reveal the physical and chemical grounds.…”

mentioning

confidence: 99%

“…[1][2][3][4] Understanding the origin of the photoluminescence (PL) of SiNCs is fundamentally important, considering the possibility of their widespread applications. The surface of SiNCs containing silicon hydride groups could readily react with 1-ene compounds to form relatively stable Si-C bonds, 5,6 introducing organic functional groups on the surface, facilitating the covalent attachment of organic and biological moieties that open the potential of such inorganic nano-materials to many biological applications.…”

mentioning

confidence: 99%

Oxygen backed silicon hydride in correlation with the photoluminescence of silicon nano-crystals

et al. 2017

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Converting silicon hydride (-SiH) to oxygen backed silicon hydride (-OSiH) on porous silicon leads to a shift in the wavelength of photoluminescence (PL) maximum from 670 to 605 nm, corresponding to an increase of 0.2 eV on emission energy. The results implied that silicon hydride, which links to the surfaces of silicon nano-crystals (SiNCs) via oxygen atoms, is directly responsible for the wavelength change of the PL peak.Silicon nano-crystals (SiNCs) are one of the most attractive nano-functional materials due to their electronic and photonic properties, their compatibility in biological environments, as well as their popularity in the semiconductor microelectronics industry.1-4 Understanding the origin of the photoluminescence (PL) of SiNCs is fundamentally important, considering the possibility of their widespread applications. The surface of SiNCs containing silicon hydride groups could readily react with 1-ene compounds to form relatively stable Si-C bonds, 5,6 introducing organic functional groups on the surface, facilitating the covalent attachment of organic and biological moieties that open the potential of such inorganic nano-materials to many biological applications. 1,4,7,8 Since the discovery of the PL of SiNCs at room temperature in 1990, 9 the mechanism of the PL generation has been the centre of many studies. Various theories have been proposed in order to reveal the physical and chemical grounds. To date, however, research data have seldom led to the complete understanding of such emission. Quantum connement (QC) theory 10 proposed in earlier years has been challenged by many experimental observations, which showed that PL was inu-enced by not only geometric dimensions of SiNCs, but also surface states of chemical groups, such as silicon oxide species.11-14 Crystal defects and dangling bonds have been regarded as the causes of the PL emission, but the effect of the oxidation of surface silicon hydride was not fully accounted for.15,16 It becomes well accepted that the PL of SiNCs is a complicated process and QC theory cannot be adequately applied for full explanation. Besides surface states of chemical groups, other factors, such as particle sizes, also play important roles in the mechanism of the PL. 7,11,[17][18][19][20] Time resolved PL spectra revealed that there are two types of PL emissions from SiNCs, namely, fast decaying "F band" blue emissions and slow decaying "S band" red emissions. 21Although short life-time F band emissions were believed to be originated from the core of SiNCs, 20 both F and S bands were found to be inuenced by oxygen on SiNCs.22,23 Recently a long lived blue band and a UV band were also found to be associated with oxidized silicon.24 Although the oxidation of silicon in ambient air has been known to cause wavelength shis of PL maximum ever since the discovery of the PL of porous silicon for S band emission decades ago, the detailed mechanism was unclear. There are too many unknown factors for both S and F band emissions when oxygen is involved. Therefore, rev...

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Enzyme biosensor systems based on porous silicon photoluminescence for detection of glucose, urea and heavy metals

Cited by 107 publications

References 34 publications

Click‐Conjugation of Nanogold‐Functionalized PAMAM Dendrimer: Toward a Novel Electrochemical Detection Platform

Click‐Conjugation of Nanogold‐Functionalized PAMAM Dendrimer: Toward a Novel Electrochemical Detection Platform

Parallel Detection of Refractive Index Changes in a Porous Silicon Microarray Based on Digital Images

Oxygen backed silicon hydride in correlation with the photoluminescence of silicon nano-crystals

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