Enzyme and Immunoassays

Miller, James N.; Knopp, Dietmar

doi:10.1002/14356007.b05_129

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Clinical Chemistry1

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2010

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“…[32,33] Haptens can also be employed in place of complete antigens. The principle of immunoassays is based on a competitive and cooperative interaction between the analyte to be determined and a labeled ligand (L*), which is thus measurable, and an unlabeled ligand (L), both of which occupy the same binding site on a protein (P).…”

Section: Clinical Chemistrymentioning

confidence: 99%

Clinical Chemistry: Challenges for Analytical Chemistry and the Nanosciences from Medicine

Durner

2010

Angew Chem Int Ed

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Clinical chemistry and laboratory medicine can look back over more than 150 years of eventful history. The subject encompasses all the medicinal disciplines as well as the remaining natural sciences. Clinical chemistry demonstrates how new insights from basic research in biochemical, biological, analytical chemical, engineering, and information technology can be transferred into the daily routine of medicine to improve diagnosis, therapeutic monitoring, and prevention. This Review begins with a presentation of the development of clinical chemistry. Individual steps between the drawing of blood and interpretation of laboratory data are then illustrated; here not only are pitfalls described, but so are quality control systems. The introduction of new methods and trends into medicinal analysis is explored, along with opportunities and problems associated with personalized medicine.

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Section: Clinical Chemistrymentioning

confidence: 99%

Clinical Chemistry: Challenges for Analytical Chemistry and the Nanosciences from Medicine

Durner

2010

Angew Chem Int Ed

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show abstract

Enzyme and Immunoassays

Cited by 1 publication

References 74 publications

Clinical Chemistry: Challenges for Analytical Chemistry and the Nanosciences from Medicine

Clinical Chemistry: Challenges for Analytical Chemistry and the Nanosciences from Medicine

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