Abstract:The effect of prolonged digoxin treatment ( I mg/kg day for 8 days) on the activity levels of some enzymes of energy metabolism (phosphofructokinase, lactate dehydrogenase, citrate synthase, succinate dehydrogenase) in rat myocardium was studied. In the control animals receiving the solvent mixture (glycerol : ethano1:water in 1 : 1 : 1) a transient decrease in the lactate dehydrogenase and citrate synthase activity levels was observed. In the hearts ofdigoxin treated rats the level of activity of phosphofruct… Show more
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