Enzymatic Synthesis and Characterization of PolyQuercetin

Bruno, Ferdinando F.; Trotta, Adam H.; Fossey, Stephen A.; Nagarajan, Subhalakshmi; Nagarajan, Ramaswamy; Samuelson, Lynne A.; Kumar, Jayant

doi:10.1080/10601325.2010.518839

Cited by 40 publications

(46 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In fact, many of these properties were related to the antioxidant activities of polyphenols [7][8][9][10]. However, depending on their structure, the processability of these compounds was limited by their weak stability and low solubility in organic or aqueous solvents [11,12]. With a view to improve these properties, derivatization of phenolic compounds by enzymatic polymerization was reported by several authors [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Enzymatic Polymerization of Rutin and Esculin and Evaluation of the Antioxidant Capacity of Polyrutin and Polyesculin

Chebil¹,

Rhouma²,

Chekir‐Ghedira³

et al. 2015

Biotechnology

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Enzymatic Polymerization of Rutin and Esculin and Evaluation of the Antioxidant Capacity of Polyrutin and Polyesculin

Chebil¹,

Rhouma²,

Chekir‐Ghedira³

et al. 2015

Biotechnology

View full text Add to dashboard Cite

“…However, two new peaks, at 250 nm and a small shoulder at 350 nm, appear in the spectrum of poly(HDT). Blue shift peak at 250 from 283 nm may be caused by polymer conformation . The small shoulder peak at 350 nm can be associated with the

n \to π^{*}

transition due to the COC coupling which had been reported in enzymatic polymerization of caffeic acid …”

Section: Resultsmentioning

confidence: 70%

“…The first application of enzyme catalysis in the context of polyphenols was in the synthesis of formaldehyde‐free resin . Recently, the applications of polyphenols synthesized using enzyme catalysis has been extended to pharmaceutical and food applications such as polymeric antioxidant food additives and antimicrobials for active packaging . The use of polyphenols have also been reported in electronic, photonic and flame retardant applications .…”

Section: Introductionmentioning

confidence: 99%

Facile enzymatic preparation of fluorescent conjugated polymers of phenols and their application in sensing

Kiratitanavit

Bruno

Kumar

et al. 2018

J of Applied Polymer Sci

Self Cite

View full text Add to dashboard Cite

The recognized drawback of utilizing metal catalysts for the synthesis of fluorescent conjugated polymers (CP) is the requirement for extensive purification to ensure complete removal of residual catalyst that would otherwise quench the fluorescence. In addition, typical synthesis of fluorescent CP involves multiple steps, monomers and solvents with varying levels of toxicity. This work demonstrates the possibility of utilizing oxidoreductase enzymes as the catalyst, for the one step polymerization of naturally occurring phenols to yield fluorescent conjugated polyphenols. The metal in the active site of the enzyme remains chelated during the synthesis allowing the polymers to be fluorescent as synthesized without the need for extensive purification. Three natural phenols, 4‐hydroxyphenylacetic acid, hydroxytyrosol, and chlorogenic acid were polymerized using Horseradish peroxidase as the biocatalyst. Spectroscopic techniques, UV–vis, Fourier transform infrared Spectroscopy–Attenuated Total Reflectance, and fluorescence, are used to characterize chemical structure and photoluminescence of these polymers. The polyphenols exhibit fluorescence with significant stokes shift in the range 30–100 nm rendering them useful in fluorescence quenching‐based sensors. Preliminary studies on use of these polymers, in the detection of nitro‐aromatic compounds in solution through using fluorescence‐quenching are also presented. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46496.

show abstract

“…2) had a long wavelength tail indicating the presence of extended conjugation [25]. The thermogravimetric analysis (TGA) was used to study the thermal stability of the products of LCcatalyzed polymerization of DHQ (Fig.…”

Section: Resultsmentioning

confidence: 99%