Enzymatic ketone reductions with co-factor recycling: Improved reactions with ionic liquid co-solvents

Feruloyl esterase-catalysed synthesis of glycerol sinapate using ionic liquids mixtures

“…van , in their recent review, summarised the different types of enzymes used so far in biocat- alytic transformations in ILs (lipases, pig liver esterase, proteases, glucosidases, lyases) and claim that it is to be expected that ionic liquid-based solvent systems will have enormous potential in multicatalyst transformations. More recently, an alkaline phosphatase (Lopez-Pastor et al, 2007), three alcohol dehydrogenases (Dreyer and Kragl, 2007;Hussain et al, 2008) and a serine cutinase protease (Micaelo and Soares, 2008) were studied and found to be active in certain types of ILs. Therefore, the screening of novel enzymatic activities in ILs is critical and up to date.…”

A novel hybrid platform for the preparation of disposable enzyme biosensors based on poly(3,4-ethylenedioxythiophene) electrodeposition in an ionic liquid medium onto gold nanoparticles-modified screen-printed electrodes

“…Moreover, it was also reported that ADH [17] and Tyr [18] exhibited a good enzymatic activity and stability in this ionic liquid. As described in Section 2.3, PEDOT was synthesized under potentiostatic conditions from EDOT solutions in BMIMPF 6 .…”

Future Trends for Green Chemistry in the Pharmaceutical Industry

“…It should also be borne in mind that the application of ILs as neat reaction media may not be the optimum route to maximize any benefi ts of ILs in organic synthesis. The use of mixtures with conventional solvents or water may, for certain reaction classes, give better performance than neat ILs or pure solvents alone [47,48] . Some of the current generation of ILs show potential to be much less ecotoxic than the fi rst -generation imidazolium and high -molecular -weight quaternary ammonium/phosphonium -based materials.…”