Enzymatic degradation and immunogenic properties of derivatized dextrans

Crepon, B.; Jozefonvicz, J.; Chytrý, Vladimír; Řı́hová, Blanka; Kopeček, Jindřich

doi:10.1016/0142-9612(91)90049-g

Cited by 51 publications

(39 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The nature of modification had no significant effect on the rate of degradation. Similar results were obtained by others (ROSEMEYER and SELA 1984;CHAVES and ARRANZ 1985;CREPON et al 1991). The degradation of dextran and its derivatives with isolated lysosomal enzymes (SCHACHT et al 1988) was slower than the cleavage by dextranase.…”

Section: Principles Of Biodegr~dabilitysupporting

confidence: 88%

Soluble Polymers as Targetable Drug Carriers

Krinick¹,

Kopeček²

1991

Targeted Drug Delivery

View full text Add to dashboard Cite

Section: Principles Of Biodegr~dabilitysupporting

confidence: 88%

Soluble Polymers as Targetable Drug Carriers

Krinick¹,

Kopeček²

1991

Targeted Drug Delivery

View full text Add to dashboard Cite

“…Remarkably, biodegradable dextran hydrogels containing polyethylene glycol have exhibited regulated insulin release (138). A substantial number of pharmacokinetic studies on dextran conjugates with therapeutic and imaging agents have been carried out in animals (31,42,127,138,139).…”

Section: Clinical Applications Of Dextran and Dextranasesmentioning

confidence: 99%

Microbial Dextran-Hydrolyzing Enzymes: Fundamentals and Applications

Khalikova

Susi

Korpela

2005

Microbiol Mol Biol Rev

226

152

View full text Add to dashboard Cite

Dextran is a chemically and physically complex polymer, breakdown of which is carried out by a variety of endo- and exodextranases. Enzymes in many groups can be classified as dextranases according to function: such enzymes include dextranhydrolases, glucodextranases, exoisomaltohydrolases, exoisomaltotriohydrases, and branched-dextran exo-1,2-α-glucosidases. Cycloisomalto-oligosaccharide glucanotransferase does not formally belong to the dextranases even though its side reaction produces hydrolyzed dextrans. A new classification system for glycosylhydrolases and glycosyltransferases, which is based on amino acid sequence similarities, divides the dextranases into five families. However, this classification is still incomplete since sequence information is missing for many of the enzymes that have been biochemically characterized as dextranases. Dextran-degrading enzymes have been isolated from a wide range of microorganisms. The major characteristics of these enzymes, the methods for analyzing their activities and biological roles, analysis of primary sequence data, and three-dimensional structures of dextranases have been dealt with in this review. Dextranases are promising for future use in various scientific and biotechnological applications

show abstract

“…Studies have shown that dextran resistant to enzymatic degradation and most stable in tissue environment (Crepon, Jozefonvicz, Chytry, Rihova, & Kopecek, 1991).…”

Section: Dextranmentioning

confidence: 99%

Magnetite (Fe3O4) - Synthesis, Functionalization and its Application

Hameed¹,

Mushtaq²,

Hussain³

2018

IJFAAS

View full text Add to dashboard Cite

Nanoparticles are smaller than 100nm. Size of particle depends upon the method that is used for synthesis of nanoparticles. Magnetic nanoparticles consist of iron, cobalt and nickel and their chemical compounds. Their safety or toxicity is major concern for use in food. Magnetite, hematite and meghemite are types of magnetic nanoparticles. Magnetite (Fe 3 O 4 ) common among the magnetic iron oxide nanoparticle that is used in food industry. Magnetite is getting popular due to its super paramagnetic properties a nd lack of toxicity to humans. Different methods are used to synthesize magnetic nanoparticles. Upon contact with air these particles loses magnetism and mono-dispersibility. To overcome this problem these nanoparticles are coated with natural or synthetic polymers, metals, organic and inorganic substances to create stable and hydrophilic nanostructures. Due to easy separation with magnet these magnetic nanoparticles are used as an affinity probe to remove bacteria from different food samples and have food related applications e.g, protein purification, enzyme immobilization and food analysis. These magnetic nanoparticles also used for removal of heavy metals and used in medical field.

show abstract

Enzymatic degradation and immunogenic properties of derivatized dextrans

Cited by 51 publications

References 17 publications

Soluble Polymers as Targetable Drug Carriers

Soluble Polymers as Targetable Drug Carriers

Microbial Dextran-Hydrolyzing Enzymes: Fundamentals and Applications

Magnetite (Fe3O4) - Synthesis, Functionalization and its Application

Contact Info

Product

Resources

About